1. In this meta-analysis, vitamin D supplementation was associated with reduced ICU admission and mechanical ventilation rates in patients with SARS-CoV-2 infection. 2. However, vitamin D supplementation did not significantly affect mortality associated with SARS-CoV-2 infection. Evidence Rating Level: 1 (Excellent) SARS-CoV-2 infection continues to be a life-threatening respiratory illness even three years after the