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A pupil at St Matthew's Primary School in east Belfast has been diagnosed with tuberculosis (TB), the Public Health Agency (PHA) has said.
The PHA said screening will be offered to pupils and staff who may have been in contact with the pupil.
It said this was a precautionary measure in line with standard national guidance.
It is working with colleagues from the Belfast Health and Social Care Trust, and the school.
The PHA said an information letter and a TB fact sheet are being sent to pupils and staff.
Dr Sarah Milligan, acting consultant in health protection at the PHA, said: "TB is a serious but curable infectious disease which normally affects the lungs, but it can affect other parts of the body too.