Victory. It is going to be time for ted cruz to rethink what his Campaign Looks like tomorrow. Chuck, thanks very much. Again, were following that democratic contest as well. Well be back on the air with updates as they happen. Nightly news will continue for some now. Im lester holt, nbc news. Good evening. You just heard the latest results in tonights indiana primary. With his victory tonight, donald trump may have just dashed opponents hopes of stopping him from getting the republican nomination. So much hanging in the balance, ted cruz went personal on trump today like weve never seen him. A stinging tirade, attacking the frontrunner as a serial philanderer and so much more. Lets get to Hallie Jackson with more f reporter good evening, lester. The loss tonight not surprising to the cruz campaign. The question now, by how much. Unless its devastating, watch for cruz to stay in this race as today he lashed out against his rival. On a day that could decide the future of the republican race, intensely personal politics. The man is utterly a moron. Reporter ted cruz in his arsenal against donald trump. This man is a pathological lier. Reporter other attempts to wrestle back the narrative, less than 24 hours after cruz confronted trump supporters, trump pouncing, describes cruz as a desperate candidate trying to save his failing campaign. Arguing hes unhinged, without the temperament to be president. Cruzs own attack line turned against him. Its a question of temperament and judgment. Reporter cruzs campaign unproven tabloid story linking cruzs father to president kennedys assassination. He was with os wold prior to oswald being shot. The whole thing is ridiculous. Reporter rafael cruz himself responding. This audio, an nbc exclusive. This is nuts. Yes, my dad killed jfk, he is secretly elvis, and jimmy hoffa is buried in his backyard. Reporter through it all, today, cruz again refusing to answer whether he would support trump as the gop nominee. But senator, why not say hallie, youve asked it already. If you think hes a liar im sorry, if youre saying hes hallie, youve asked one already. Reporter trumps aides tell nbc theyre turning to november, focusing more on Hillary Clinton starting tomorrow. Trump trailing clinton by six points in a hypothetical national matchup. His Campaign Already looking past its seventh straight win. Lester . Hallie jackson tonight, thanks. Meantime, Hillary Clinton is not in indiana tonight, where the democratic race as we mentioned a moment ago is too early to call. Instead, shes setting her sights on the general election. Unleashing new attacks on donald trump in an interview with nbc news. A likely preview of the potential clashes to come. But as nbcs Andrea Mitchell reports, Bernie Sanders and his supporters are showing no signs of going anywhere anytime soon. Reporter tonight Bernie Sanders feeling confident in indiana. I dont think that a little bit of rain will keep people in indiana from casting their votes. Reporter sanders has been drawing huge crowds. Hillary clinton campaigning in ohio and West Virginia today. Im really focused on moving into the gera but declaring victory down the road, saying shes ready to take on donald trump. He appears to be ready to dump a whole lot of stuff on you. People have been dumping stuff on me for 25 years. And here i am, on the brink of being the first woman nominated by a National Party to run for president. Reporter the likely campaign to come. When i listen to donald trump say some of what hes saying about Foreign Policy and national security, even i find it scary. Is he unqualified to be commander in chief . Hes given no indication he understands the gravity of the responsibility of being commander in chief. Reporter on the paid speeches to wall street, even president obama making fun of her refusal to release the transcripts. If this material works well, im going to use it at Goldman Sachs next year. What is in that speech that you wouldnt want to reveal to the people voting for you . Nothing. You know why not just put it out there . Well, know that others, including mr. Trump, have made speeches. And look at where we are. Ive put out 33 years of tax returns. Reporter here in West Virginia, clinton struggling with the White Working Class voters, thats a group that has been going strongly for sanders in some contests. Those voters could also be key to the outcome in indiana tonight. Lester . Andrea, thank you. Lets bring in our political director, the moderator of meet the press, chuck todd. This could be a big win for donald trump tonight. It doesnt get him over the delegate number he needs for the nomination. How close is that in reach . Its now more within reach than ever. Before tonight he needed less than half of the remaining delegates. Now, i think its fair to say, look, hes not technically the presumptive nominee, he doesnt have the delegates in hand that he needs, he still needs the california primary and the last day of primary season to get over the top. But i can tell you this, after tonight, effectively, republicans n t with this fact, donald trump is going to be the republican nominee. Its going to take some collapse for that not to be the case. Chuck todd, thank you. A u. S. Navy s. E. A. L. Was killed today during an attack by isis fighters in iraq. A combat death at the hands of isis years after the end of americas combat mission there. It comes at a time when u. S. Military forces are expanding their role inside the country. As our chief Foreign CorrespondentRichard Engel tells us. Reporter the latest american killed was a navy s. E. A. L. , based in san diego. He was working with kurdish fighters operating north of the isisheld city of mosul. This Service Member died when isil terrorists penetrated a checkpoint. Reporter a kurdish soldier said the american was driving in this Armored Vehicle hit by an isis rocket. The u. S. Military said he died after being shot. U. S. Military Officials Say the isis attackers armed with light wpo break through kurdish lines, and get two miles into kurdish territory. The u. S. Later wiped them out with more than 20 air strikes. Two u. S. Troops had already been killed since the battle against isis began. About 4,500 american troops are now deployed in iraq and syria. Their numbers have grown slowly, but steadily. Not how president obama long said he wants to be remembered. I mean what i say. I said id end the war in iraq. I ended it. Reporter in baghdad last month, lester asked the defense secretary where this was all heading. As you add additional personnel, and they are advising lower down the chain, does that put more americans at higher risk . The iraqis are still in the lead. That doesnt change. And lester, americans are at risk today. Every single day as secretary of defense, i take that more seriously than anything else. Reporter but no matter how seriously, inevitably as more troops are sent into battle, more casualties will follow. Lester . Richard engel tonight, thank you. For the second day in a row, more than 45,000 students missed class in detroit, as the citywide sickout remained schools to be closed. Blake mccoy explains why the teachers are so furious at the city as they refuse to come to work. It also tells us about the impact on the children. Reporter fed up and facing no pay. Detroit teachers staged a sickout for a second day. Teachers like Lorraine Sheffield and deborah robinson. Theyve got to take us seriously. Were not a rug. Were not under anyones feet. We shouldnt be treated like that. Reporter lorraine and deborah, like many teachers in detroit, choose to have their compensation spread out year round, during summer break. With the deeply indebt district running out of money june 30th, those summer paychecks wont come. That is the money that takes care of us across the summer. Reporter nearly every school in the district has been forced to close this week, with more than 1,500 teachers calling out, more than 45,000 students staying home. Michigans legislature is working on a restructure plan to bail the district out. The governor today said the sickouts are making that harder. I would hope they would get back in the classroom, because the kids come first. Reporter in detroit neighborhoods, an unscheduled spring break. How many of your parents went to work and left you home . All of us. Reporter the few parents who are home i agree they should be paid. At the same time they should find alternatives for the kids instead of having them out here with so much free time. Reporter late word tonight the union is encouraging its members to return to work tomorrow, saying written guarantee that teachers will be paid through the summer. On this National Teacher appreciation day, here in detroit, teachers have felt very underappreciated. Lester . All right, blake, thank you. Its been a trusted brand used in homes all across america for decades. But now Johnson Johnson has lost yet another multimillion dollar lawsuit, which claims an ingredient in its popular baby talcum powder causes cancer. There are more than 1,000 other suits pending. We get more on all this from nbcs rehema ellis. Reporter for more than 100 years, Johnson Johnsons baby powder has been promoted and widely accepted as safe. But now the company lost its second major lawsuit this year in a st. Louis courtroom. Johnson johnson was ordered to pay 55 million to 62yearold gloria, who said she used the companys baby powder with talcum as a feminine hygiene product for 40 years. She blames the tal for causing her ovarian cancer. And sued Johnson Johnson for failing to warn about the possible risks of talcum. She was using a product that she thought was perfectly safe. Had no idea that it might be dangerous. And that that product then had some causation for her cancer. Reporter jurors were shown documents plaintiffs attorneys argued Johnson Johnson knew about the risks and downplayed them. I think thats extremely uncaring, shows no concern whatsoever for the safety and welfare of the people they are selling to. Reporter the Company Issued a statement saying, multiple scientific and regulatory reviews have determined that talc is safe for use in cosmetic products, and the labeling on johnsons baby powder is appropriate. The American Cancer Society says, the research is inconclusive, but concerned women may want to avoid using the product with um if they want to use some powder, cornstarch would be an alternative. Reporter the company says it will appeal the case, and defends the safety of its iconic baby powder. Rehema ellis, nbc news, new york. Still ahead tonight, a new warning about when you should and should not take antibiotics. What experts say doctors are doing all across the country that needs to stop. The mystery involving one of the most Iconic Images of world war ii. Have we all believed the wrong thing about it for decades. Were back now with a new warning about the antibiotics millions of americans take. Researchers at the cdc say nearly onethird of those antibiotics prescribed by doctors every year are unnecessary. And all this overprescribing is only helping create dangerous drugresistant super bugs. So when do you need an antibiotic, and when dont you . Nbcs tom costello has details. Reporter like most twins, charlotte and clair share almost everything, including colds and ear infections. But their mom doesnt believe in pushing the antibiotics. Theyre getting so many more illnesses at this age than my husband and i do, that it would just be overkill and overuse. Reporter smart, say researchers, who today reported a stunning 30 of outpatient antibiotic prescriptions are unnecessary. 47 million prescriptions each year. The conc overprescribed, dangerous super bugs are growing immune to them. We dont want to be faced with a situation where were trying to treat an infection that is so resistant, we dont have any antibiotics to use. Reporter children 3 and under receive the most antibiotics. Often for ear infections which are usually viral and dont even respond to the drugs. But parents still want them. Meanwhile, researchers say healthy adults can often fight off bacteria infections on their own. 40 of outpatient outpatient antibiotic use for ear, sinus or respiratory infections, more than half are unnecessary. When are they needed . When painful sinus infections cause fever or coughs last more than 14 days. Or an ear infection with pus. These are when were treating patients. Reporter in washington, they take approach. The overall goal is to walk the line between adequately treating people and minimally exposing them and the population to the drug. Thats a fine line. It is. Reporter the cdcs goal . Cut unnecessary antibiotic use by 50 within four years. Or we may soon have far fewer antibiotics that work. Tom costello, nbc news, washington. Were back in a moment with how the smash hit musical about history just made history of its own. Theres a new theres a new development tonight about one of the most famous images in u. S. History, the flagraising on iwo jima during world war ii. The marines are now looking at new evidence of who actually raised that flag, and the famous son of one of them says for the first time hes convinced the marines got it wrong. Nbcs Pete Williams with the stunning new twist. Reporter as u. S. Marines stormed the island of servicemen raised the u. S. Flag, and the photo of that moment became one of the most famous in history. For seven decades the marines identified five of their own in that mipicture, along with bradley. Now amateur historians say john bradley was not among those six men cast in bronze. His son, james, wrote the bestselling book, flags of our fathers, made into a hit movie directed by clint eastwood. Now for the first time bradley tells nbc news, he believes his father was not in the iconic photo after all. For 70 years, the government has been saying that was my father there. So it took me a little while to realize that might not be so. Reporter a smaller flag had been raised on iwo jima two hours earlier. Amateur historian Justin Spence of sacramento studied recently released combat photos for identifying details. It can be little things. A helmet, or a ring on a finger. Reporter he discovered the marines failed to name two of those who raised that first flag, including Navy Corpsman john bradley. Bradley did not wear a cap and rolled up his leg cuffs. After he was dead, we didnt realize he was talking about the first flag raising. Reporter the marine corps said its humbled by the sacrifice by all those who fought on iwo jima, its now looking at the new evidence about its most famous image. Another big day for a little show you might have heard a thing or two about called hamilton. The broadway smash scored a recordbreaking 16 tony nominations, with the show nominated in just about every category to compete in. Including, of course, best musical. When we come back, breaking barriers. Meet the unlikely artists behind some of our Favorite Movie magic. Finally tonight, a small school near hollywood getting rave reviews for its work on blockbusters, and for the artists who developed just five years ago, exceptional minds is training young adults with autism on Digital Effects and changing lives in the process. Nbcs erica hill takes us there. Reporter the artist in this classroom are shattering stereotypes. No motion. Reporter and taking control of their future. Our whole goal is to get them employed. Reporter exceptional mind is a nonprofit Vocational School for young adults with autism. Focused on graphic and visual art. Why visual effect and animation . Why is this such a good fit . Theyre all different. Every one of them is going to have a different fit. But for the guys we look for, theyre very visual. Theyre also kind of obsessive at times. Reporter the threeyear program in Digital Effects trains students in several areas, including roto scoping, painting out tiny details one frame at a time, and time work, jobs that require a attention to detail. Graduates have lent their skills to blockbusters, like the most recent hunger games films. Eli cast, a 2014 graduate, now works in the schools studio. The client wants us to have the face looking clean without the snow. Reporter he walked me through a recent project for hbos game of thrones. Whats it like for you when you see your work . I feel thrilled. I just like to point out, oh, hey, theres my shot. Reporter theres also a strong focus on social skills and teamwork. This is what filmmakers do. They Work Together with others. And know the real meaning of friendship by accomplishing things together. Reporter demand is high for both the programs, there are at least three applicants for each slot, and for their work. This program has well exceeded my wildest expectations. We have three of our young adults have moved out of their parents homes and are working fulltime. Were just totally blown away. Repte says one frame at a time. Erica hill, nbc news, los angeles. That will do it for us on a tuesday night. Im lester holt. For all of us at nbc news, thank you for watching, and good night. [ soft music ] e. T. Phone home. When you find something you love, you can never get enough of it. With xfinity x1. Are these actually lights in the dress . Ha ha. I almost didnt recognize you. Something different. A whole lot went down as