Good evening. Tens of millions of people in the eastern half of the country woke up in the danger zone today. That rush of siberian air we were warned of came in with a vengeance. Its led to at least 25 deaths as temperatures have free fallen. In all 27 states have seen below zero temperatures today. Not the windchill, the actual temperature. Pelston, michigan, 35. Frankfurt, kentucky, minus 21. Lynchburg, virginia, 11 below. Just some of the eye watering lows. This seasons unrelenting snowstorms now the waves of arctic cold are pushing people and all the things we depend on to the breaking point in so many places. And the danger is only increasing. We start in nashville tonight with nbcs gabe gutierrez. Hello, gabe. Reporter lester, good evening. Multiple crashes are being reported across nashville right now during the evening commute. Earlier today we saw snow, right now sleet and later tonight freezing rain is expected. Across the country more than 500 daily record lows have been broken this week. Record shattering cold is spreading across the nation tonight. This is the worst ive ever seen. Reporter today, 21 states hit temperatures in the double digits below zero. Lexington, kentucky negative 18 degrees, the citys coldest day in 21 years. Cleveland saw negative 17, the ever. Flint, michigan, negative 25 degrees. Windchills today well below zero triggered massive water main breaks in nashville. 18 people in tennessee have died during this cold blast. Its heart wrenching for our responders. Were doing the best that we can. Reporter today we rode along with ems. We cant get to people. Thats our problem. Reporter this week a dialysis patient died before help could arrive. Today, as more snow fell more trouble on the way to a car accident. The icy roads slowed down this state trooper who had engine trouble, blocking this ambulance before it could reach the crash scene. Further south even florida is fighting the freeze. 42 degrees this morning, that bitter cold already threatened next years citrus crop, those florida oranges. Once the ice gets inside and the actual juice content inside starts to ice over, then the actual quality goes down. Reporter in northeast ohio an out of control car slammed into a Police Cruiser as the officer was helping another crash victim. 119 roof collapses in massachusetts, like this one in westport. Several horses had to be rescued. In revere a pair of dogs pulled from the frozen marsh. On hands and knees to get to them to clear off quickly. Reporter lake erie is 98 ice covered. Potomac river has coast guard cutters making way for commercial ships. Tonight, the deep freeze is getting deeper. Gabe gutierrez, nbc news, nashville. Reporter this is Kevin Tibbles in chicago. The cold winter wind could blow as much as a 5 billion chill into the nations economy. When boston hunkers down, tables sit at christophers restaurant. We typically see between 120 and 150 people. Thats the norm. This evening were probably going to seat about 50 or 60 people. People stay home. They cocoon, and that money does not move. When that money doesnt move, its just bad for the economy. And its not recoverable. Reporter the transportation sector has been hit especially hard. Air travelers paid out 993 million in extra costs due to cancellations. New england car sales plummeted 33 . And governments will spend 2 billion on snow and ice control. Snow bound canton, massachusetts is already 400,000 over budget. In the last four weeks weve gotten 30 inches 24 inches 25 inches and 23 inches. Reporter in frigid canton, ohio people wait for tow truck driver earl mullens. Ive seen more bad batteries this week than anything else. Reporter the business of jump starting cars has more than doubled. How do you stay warm . Just keep moving. Reporter for d. D. Lewis in chicago, school snow days mean interrupted workdays for mom. It adds to the stress not having those dedicated hours i would normally have when the School Schedule and my daily schedule gets thrown off. Reporter still aarons back may be sore, but his wallets full. He shovels snow as a professional tasker for task rabbit. Ive done about, i dont know how many hours, probably around 100 hours worth of shoveling and other tasks in the last three to four weeks. Reporter and as costs mount as winter marches on, many analysts say we actually may be in better shape than we were last year. That was when, lester, you may recall the polar vortex settled in over a much larger portion of the nation. And that wound up costing the economy some 15 billion. Lester. Kevin tibbles in chicago tonight. Thanks. In most cities across the eastern half of the country 42 degrees would be a dream right now. But this morning was downright frigid for folks used to the heat in miami. Al roker is in miami beach with a look at what all of us can expect as we head into the weekend. Al, whats the word . Reporter lester, good evening. Here in florida, southern florida, miami, temperatures got up into the low 60s. Elsewhere around the state 40s and 50s. But overnight lows dropped well below freezing. That gave a lot of concern to Citrus Growers and will again once more tonight. However, look at these overnight lows throughout the northeast. We expect to see temperatures anywhere from 10 to 30 degrees below normal with windchills well into the negative double digits. And here comes another winter storm. Cincinnati, for example, youll be looking at snow arriving about midnight. Four to eight inches of snow, a tenth of an inch of ice. Ends as rain. As we move into early sunday morning snow developing from new york to boston. About one to three inches of snow. Snow changing over to ice or rain. Snowfall totals generally about six to nine inches. And the ice storm is a big problem. Were worried about this from missouri all the way into maryland. Dangerous ice. So our winter continues, lester. And guess what . Weve got not one but two more reinforcing shots of cold air coming in next week. Al roker, thanks. There is an urgent global appeal tonight from authorities in the uk. Theyre sounding the alarm about three teenage schoolgirls who have vanished from their families without warning. Only to turn up on camera together at the airport. And there are worries they have been lured to join isis. As hundreds of young women across europe have done. We get late details tonight from nbcs katy tur in london. Reporter the three girls walked through security at londons gatliff airport showing no hint of their intentions. They flew to istanbul, bound for syria, officials fear, to join isis. 15yearold shamima begum, Kadiza Sultana 16 and another 15yearold parents asked not to be named raised alarm bells when they didnt come home tuesday night. These families had no idea of the intentions of their daughters. No idea whatsoever they were going to be traveling to turkey and that they intended to go to syria. Reporter they were known as normal teenagers, good students. But on begums twitter account, a message to a female isis member, a known recruiter asking for a private conversation. All of that triggered scotland yards unprecedented alert and it comes amid growing concerns that more and more young people are being enticed by isis, including we just learned another 15yearold girl from the same school who ran off in december. Theyre not the disaffected. Theyre not necessarily the unemployed youth. Instead were seeing educated young women who are engaged in politics. Reporter and isis makes them think it offers something worth fighting for. I think the idea that you can give your life meaning by performing jihad and thats very exciting. Reporter experts say perhaps more than 300 women from across europe have joined isis. Many of them from the uk. As for the latest three, loved ones hope this harsh istanbul winter has delayed their journey and kept them out of isis hands. Katy tur, nbc news, london. Also overseas, a developing story tonight. Late pictures coming out of a dramatic highrise fire in dubai. Its a major multistory blaze in an apartment building. Incredibly its known as the torch. It towers more than 1,100 feet above that citys marina. Its one of their tallest residential buildings in the world. Almost as tall as the empire state building. Police and firefighters are on the scene. The building has been evacuated. There are no word yet on any casualties. Facing a storm of controversy over his assertion that the president of the United States doesnt love america, the former mayor of new york Rudy Giuliani isnt backing down. In fact, hes doubling down. And the white house is hitting back hard. Our senior White House CorrespondentChris Jansing with more on the war of words. Reporter the man once known as americas mayor, Rudy Giuliani, now the target of a biting attack from the white house. Its sad to see when somebody whos attained a certain level of public stature and even admiration tarnishes that legacy so thoroughly. Reporter the backlash growing after giuliani said wednesday night, i do not believe that the president loves america. Then last night on fox doubled down. Im right about this. I have no doubt about it. I do not withdraw my words. I do not detect in this man the same rhetoric and the same language, the same love of america that i detected in other american president s including democrats. Reporter but today at a meeting of the Democratic National committee, the president used this language. Its about making this nation we love more perfect. Reporter the white house denies that was a response to giuliani, though the Hashtag Obama loves america was started by the white house and tweeted more than 54,000 times in 24 hours with comments from both sides. And the president s spokesman wasnt done. I think really the only thing that i feel is i feel sorry for Rudy Giuliani today. Reporter there are now calls for Rudy Giuliani to apologize, but i just spoke with him. He told me he absolutely will not apologize for saying what he truly believes. He also said he never intended to question the president s patriotism. Lester. All right, chris, thank you. Two people are already dead, others are clinging to life tonight after apparently contracting a terrifying superbug at a major california hospital. Were now learning more about the patients and searching for answers about how this drugresistant bacteria found its way from victim to victim. A closer look tonight from nbcs hallie jackson. Reporter the superbug that infected seven people at Ucla Medical Center has kept an 18yearold man in the hospital for months. To call this an ordeal, i think, is an understatement. Reporter attorney pete kaufman represents his family. Were talking about an infection on steroids. Its highly resistant to treatment. So youre gravely, gravely ill for a long period of time. Reporter officials at ucla wouldnt address specific claims citing patient privacy, but doctors have notified nearly 200 people about possible exposure to a bacteria called cre, after an investigation last month connected infections to instruments used in a special kind of endoscopy. The complex devices can be hard to decontaminate. Ucla followed all of the recommended procedures for cleaning the scopes. Reporter now though the hospital goes above and beyond whats recommended, just like doctors at this suburban chicago facility which had an outbreak of the same superbug. When you have a process thats sufficiently complex like that, there are ample opportunities for the Human Element to step in and not have everything go exactly according to protocol. Reporter the maker of the endoscopes used at ucla says its adding things like checklists to decontamination guidelines and monitoring concerns closely. But for the patients already, the biggest concern now is recovery. Hallie jackson, nbc news, los angeles. We will likely hear closing arguments soon in the trial of the man accused of killing american sniper chris kyle. Today the prosecution brought up rebuttal witnesses including a psychologist claims a defendant knew what he was doing was wrong. Nbcs jacob rascon has been following the trial for us in stephenville, texas. Reporter for the first time during his capital murder trial, Eddie Ray Routh appears to be watching closely. More than 30 witnesses have testified including chris kyles widow, taya, members of the routh family and law enforcement. But now rouths Mental Health is up for debate. Two years ago during what was meant to be a therapy session to help him cope with ptsd, routh shot chris kyle and chad littlefield at a texas gun range and fled in kyles truck finally surrendering and later confessing in a rambling 50minute video. The defenses Mental Health expert tells the jury routh suffered from schizophrenia at the time believing pigs were taking over the world. Saying his victims were pig hybrids and assassins. The psychiatrist told the jury after leaving the marine corps routh checked in to Mental Health centers many times including the v. A. And was diagnosed with psychosis, ptsd, depression, Mood Disorder and Substance Abuse problems. But experts on both sides downplayed ptsd as a possible factor in the crime. The insane defense in particular in texas is a very narrow defense. Often becomes a battle of experts and the extent by which the jury gives weight to their testimony. Reporter the prosecutions expert told the jury routh was not insane but high. He admits to smoking pot and drinking whiskey before the crime. And he admits he was angry at his own wife and at his victims because they wouldnt talk to him. The former marine who spoke of the apocalypse upon his arrest now awaits his judgment day. Routh has pleaded not guilty by reason of insanity. The trial now in its final days as the movie american sniper, about one of its victims, will be competing at the oscars this weekend. Kyles widow taya is expected to attend and be back next week in time for closing arguments. Lester. Jacob rascon tonight, thank you. Surprising turns in a deadly road rage mystery in las vegas. Still to come, that mother gunned down, a teenager under arrest. And tonight, new revelations about a violent encounter. And later some good news on a friday night. A girl scout who just struck gold by going doortodoor in a very unusual place. Ld by going doortodoor in a very unusual place. [ man ] i remember when i wouldnt give a little cut a second thought. When i didnt worry about the hepatitis c in my blood. When i didnt think twice about where i left my razor. [ male announcer ] hep c is a serious disease. Take action now. Go to hepc. Com or call 1844444hepc to find out how you and your doctor can take the next step towards a cure. Because the answers you need may be closer than they appear. My feet felt so heavy at the end of the day. They used to get really tired. Until i started gellin. I got dr. Scholls massaging gel insoles. When theyre in my shoes my feet and legs feel less tired. Its like walking on a wave dr. Scholls massaging gel insoles, im a believer fact. 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Reporter that was news to police. Please keep in mind this investigation is still dynamic and ongoing. Reporter detectives were told meyers was taking her daughter home after driving lessons when she was cut off by a vehicle nowsch was driving. Meyers picked up her adult son armed with a handgun, to look for nowschs car the suspect followed the meyers home where police say 22 shots were fired, ending tammy meyers life. It is believed hes the only shooter, but there is another suspect involved in the incident. Reporter new documents say nowsch called a friend to pick him up and boasted to friends about the shooting. Jonathan lee lives across the street from nowsch and says the suspect is not a bad person. I know he wouldnt do anything like that on purpose or intentionally. He even cried about it after he did it. Reporter tonight, new details in an evolving case where the victim and the suspect may be the only ones with answers. Miguel almaguer, nbc news, las vegas. 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Reporter there but for the grace of chapped lips go aye you heard her right. This rosy cheeked red blooded norwegian is hustling sugar on the ice. Hello. Do you want to buy some Girl Scout Cookies . Reporter fishermen startled at the sight of two 10yearolds pushing cookies in the sleigh had no choice. Ill get you change real quick. Reporter seriously, inga its like shooting fish in a barrel. I think its a great id though. For sure. Ice fishermen always looking for snacks. Why not . Reporter one down, on to t next. Keep walking. Reporter inga runs a tight sled. We were wondering if you would like to buy some Girl Scout Cookies. Reporter same pitch, same result. Thank you. Thank you. You guys have a great day. You too. Reporter and just like that inga gets closer to the quota, and ruby tags along. Kids have a funny way of making you change your lens. Because you and i, we saw a quiet lake. Those two, they saw girl scout gold. Jana shortal for nbc news chisago lake, minnesota. That will do it for us this friday night. Im lester holt for all of us at nbc news. Thank you for watching. Have a great weekend and a good night. Lights camera access. One time in a war zone in argentina in the faulklands. I had to make a decision. I dragged them off. Says a partisan witchhunt or fair to compare bill