Is the vaccine less effective in people who take statins . The provocative new research leaving so many asking what to do. Nightly news begins right now. This is nbc night lu is in with lester holt. Reporting tonight from los angeles. Good evening. For the second time in this country in as many months, the frightening sight of smoke pouring from a burning commercial passenger plane had many fearing the worst. As it was, several of the more than 100 people aboard were injured while trying to flee a booing 767 engulfed in thick smoke after an engine burst into flames at ft. Lauderdale Hollywood International airport in florida. It happened as the jet was awaiting takeoff on a flight bound for venezuela and comes weeks after a similar incident involving a british jetliner in las vegas. Kerry sanders is at the airport with late details. Reporter dynamic air flight 405 just pulled away from the gate leaking fuel. Dynamic, out of the left engine looks like its leaking a lot of fuel. Reporter within moments, the left engine erupted in fire. Engines on fire reporter doors opened, slides deployed and passengers scrambled for their lives. We saw the fire, people started freaking out. I heard loud bang. Light, saw flames. Ran to the front of the aircraft. I heard people screaming, running to the front. Im like whats happening . I turn around and look in the window and its like flames all over the turbine of the reporter people recorded the billowing smoke. This woman says they took us out. It was an am ernlg si. The plane was on fire. Calmly, very calmly opened, smarted the procedure opening the door. The plane was still moving when this was going on. Reporter in all, 101 passengers and cry evacuated the boeing 767 in just six minutes. In all, paramedics and Emergency Physicians treated more than 20 passengers. One in serious condition with a head injury. Most believed injured in the panic to escape, not by the fire. Firefighters had a long line where it appears a trail of fuel had been drifts from the plane before it caught fire. Dynamic air based in greensboro, north carolina, is a Charter Airline that only began operations from ft. Lauderdale to south america about six months ago. Dynamic air is a small Charter Airline with only five planes in its fleet. Tonight they have a representative here to answer questions for the National Transportation safety board. Ntsb has a team here to examine the aftermath to determine what went wrong. Meantime, as the here for several hours today, 182 flights were delayed, 42 canceled. Lester . Scary moments. Kerry sanders, thank you. There is fastmoving fallout from that dramatic confrontation in boulder. Jeb bush struggling in the polls and needing a big breakout moment. He got one, but not in the way he imagined. He went on the attack against his onetime protege marco rubio leaving bush reeling, donors frustrating and some wondering if his campaign is nearly over. We have it covered beginning with Hallie Jackson. What are you hearing . Reporter lester, nbc news has learned jeb bush promised his donors today he will work to get better as a candidate and debater. That Conference Call an attempt to calm donors nerves as marco rubios team looks to recruit any shaky bush support. Loyal bush backers feel frustrated. They see a way for bush to win, but not jeb bush, now forced to answer whether today marks the beginning of the end for his campaign or the beginning of a comeback . Its not on life support. We have the most money. We have the greatest organization. Were doing fine. Reporter bush on defense after what many viewed as a dismal debate night defined by this moment, a punch that didnt land against marco rubio and his missed senate votes. You can campaign or just resign and let someone else take the job. Let me tell you, i dont remember you ever complaining about john mccains vote record. The only reason youre doing it now because we are running for the same position. Someone convinced you attacking me will help you. Reporter bush put his onetime protege on notice. People ought to show up and work. Reporter a strategy agitating supporters. The Republican Party isnt going to like a personal argument coming out of jeb bushs mouth. Reporter he has money muscle. His brother fundraising for him in washington today. I dont believe washington should be our master. Reporter they could defect if something doesnt change soon. You never want to answer questions the day after the debate whether your campaign is on life support or not. Reporter the calls to reset his message coming after months of falling fortunes for the former favorite, the sixmonth slide taking a toll on his attitude. Ive got a lot of really cool things i can do other than sit around being miserable. Reporter the campaign acknowledging it needs to adapt, shifting focus to New Hampshire where today he picked up a key establishment endorsement. And establishing a confidence he hopes supporters will feel. Hallie jackson, nbc news, reno. This is Peter Alexander in washington where ted cruz, fresh off a commanding debate performance is looking to make his next stand. The texas senator abruptly postponing a Campaign Swing through nevada, instead rushing back to capitol hill to rail against a bipartisan budget deal. Nbc news learned cruz and marco rubios campaigns have seen a fundraising spike, roughly 1 million each since last night where cruz unleashed a missile against the media and moderator. Look at the question, donald trump, are you a comic book villain, ben carson, can do you math . How about talking about substantive issue . Cheered on by the republican crowd. Democrats have the ultimate super pac called the mainstream immediate yachl. Reporter the New York Times on Chris Christie to drop out. Cant read the article because i dont have a subscription. Im not going anywhere. Hours after this impassioned appeal about misplaced priorities. We have people out of work, we have isis and al qaeda attacking us, and we are talking about fantasy football . Can we stop . Reporter Carly Fiorina tried to regain momentum. I may not be your dream candidate just yet, but i can assure you im Hillary Clintons worst nightmare. Reporter a trump versus carson showdown never materialized. We get along very well. We are laughing at another other last night. Reporter both campaigns claiming steady performances. Trump is not in any sort of trouble. He still has enviable poll numbers and still the Republican Partys frontrunner. Hes the one to beat. Reporter tonight rnc chairman strongly criticized cnbcs handling of the debate said they are considering format changes for future debates to encourage more candidate exchanges and fewer confrontations with moderators. For its part, cnbc says people who want to be president should be able to answer tough questions. Peter alexander and Hallie Jackson tonight, thanks. Lets bring in our political director and moderator of meet the press, chuck todd. Everybody wants to read so much into what happened in that debate last night. Though are going to go at it again in less than three weeks. Is it your bet well see the same people on the stage next time . I do think well see the same candidates at this point. There is no reason to get out now. You have that one debate. Its coming up literally in about two weeks. Why not stick around . We are not going to see this field whittle until about thanksgiving. Here what is we learned last night we know the establishment wing of the party is looking at jeb bush or marco rubio and the backups are kasich and christie. We know that the outsider lane of this primary is carson, trump and ted cruz. Now i think what we are going to learn the next three weeks, can jeb bush right his ship . The pressure is really on him. Its on him to perform with donors, on him to perform with voters. The next debate, as important as this one was, now the next one is even that much more important. Look, theres still a fluid field and plenty of time, but the pressure is on a lot of these candidates. Jeb bush, first and foremost. Chuck, thanks very much. You got it. A new era in washington as congressman paul ryan officially succeeds john boehner as the new speaker of the house, second in line to the presidency. Its a big generational shift, as well. Ryan becomes the first speaker born in the 1970s. Can the onetime vp candidate finally break the logjam and get congress to work . Nbcs Kelly Odonnell is on the hill where ryan said today, the house is broken. Reporter today the path to change in washington crossed a generation. Outgoing House Speaker john boehner ends a quarter century in congress. No longer bashful about tears. I leave the way i started, just a regular guy, humbled by the chance to do a reporter at 45, with school age kids, paul ryan becomes the 1869. But this handover comes from a deep conflict within their own Republican Party. A Tea Party Wing that resisted boehnered a every turn and starts on fragile footing with speaker ryan. I faces conservative demand on no action on immigration and more fight over ideology like blocking funds for planned parenthood. We are not settling scores. We are wiping the slate clean. Reporter a day of ceremony, and yes, selfies. Mitt romney who chose ryan as a running mate. I think he would be a wonderful speaker of the house. Reporter boehners exit clears the way for a fresh start, but a new era is on ryans shoulders now. Kelly odonnell, nbc news, the capitol. There are a lot of questions remaining tonight about how an expensive unmanned military blimp got loose and drifted across two states wreaking havoc along the way. Now that its back down to earth, our tom costello tells us the military is using rather unconventional methods to retrieve it from where its stuck. Reporter shotgun blasts in the pennsylvania countryside as the military pumped more than 100 rounds into the top secret blimp to let the last of the helium escape. Then the delicate job of cutting it out of the trees. Crews did manage to roll up the tail section which separated from the blimp. The milelong tether that snagged utility lines causing 30,000 to lose power also cut into sections and carted away. Biggest challenge is the fact its a very steep terrain down there. There is a stream that runs through site. Its heavily wooded. Reporter it may take military helicopters to lift the rest of the blimp out of the forest. The pentagon now reports the blimp costs 235 million, not 1. 3 billion as it first said. A test program for a 360degree airborne radar watching the east coast for enemy missiles or drones. It was turned off in april and never spotted a protester flying a gyrocopter to capitol hill. The army cant explain how the blimp broke free and drifted 150 miles across pennsylvania. Local residents are nearby Nuclear Power plant. Im surprised it got this far. I cant understand that they werent able to control it somehow to bring it down. Reporter and coming down here of all places, where the amish spurn all things modern. Things are quiet here. We see a turkey or deere, but we dont see blimps. Reporter the military will likely use a chinook helicopter to lift the blimp out of the forest. Its about 10,000 pounds and they want to clear away as much of the vegetation and trees as they can so they dont cause more damage as they lift it up and out. Tom costello in pennsylvania, thank you. Concerns about taking statins that millions use to lower their cholesterol and the effect those drugs may be having on your flu shot. We want to bring in our medical contributor dr. Natalie azar. Do they lessen the what are people supposed to do . We are not sure yet. This might be a case of drugs having an unintended consequence. You have a good set of drugs. They have a negative outcome, we are trying to investigate it whether thats the case. These two reported studies today suggest perhaps the people who use statins could have a dampened response to the flu vaccine and also which could render them less effective. I think a really Important Message for people to understand is that this is far from definitive. This is we are not recommending if you wa, nt to get the flu vaccine to stop your statin. This is something to discuss with your physician. If youre over the age of 65, you want to ask for the high dose vaccine, as well. Dr. Natalie azar, good to have you here. Hot off the trail. Potential break of a manhunt of a fugitive accused of shooting police in two states. A man they call extremely dangerous. Terrifying moments high above the ground when a skydiver gets trapped underneath sometimes the present looked bright. Sometimes romantic. There were tears in my eyes. And tears in my eyes. And so many Little Things that we learned were really the biggest things. Through it all, we saved and had a retirement plan. And someone who listened and helped us along the way. Because we always knew that someday the future would be the present. Every someday needs a plan. Talk with us about your retirement today. Cant afford to let heartburn get in the way . Try nexium 24hr, now the 1 selling brand for frequent heartburn. Get complete protection with the new leader in frequent heartburn. Thats nexium if you have high Blood Pressure like i do, many cold medicines may raise your Blood Pressure. Thats why theres coricidin hbp. It relieves cold symptoms without raising Blood Pressure. So look for powerful coricidin hbp. Hold the phone. Because at t and directv are now one which means you can access your dvr at the dmv. Change channels while he changes pants. You dont have to be a couch potato, you can be a train potato and let them watch all the shows they love, inside the ride that you really kind of hate. P introducing the all in one plan. Only from directv and at t. A fugitive considered armed and dangerous may have been spotted in southern kentucky. A manhunt was launched after the suspect wanted on drug warrants allegedly shot an officer. Schools were closed in the area for three days as police, the fbi and u. S. Marshalls searched. Now as our Gabe Gutierrez explains from springfield, tennessee, they may have the break theyve been waiting for. Reporter tonight, an active search in cumberland county, kentucky, for 62yearold byrd cook after a possible sighting late today. The manhunt began saturday afternoon. Police say cook, a convicted rapist and robber, opened fire on an officer during a traffic stop near the tennessee kentucky bozerder. The bulletproof vest saved him but cook escaped and disappeared after a shootout with a trooper later that night. Hes definitely armed and extremely dangerous. He will grow increasingly desperate over the next several days. Reporter since then, the u. S. Marshalls office and fbi joined the search with neighborhoods in were still searching. John overnight in white house, tennessee, two of cooks known associates were arrested after a foot chase. Their car spotted at a gas station. Cook was initially believed to be inside. My husband saw a shadow over behind that shed over there. Reporter betty saw one of the suspects running through her yard and called 911. Police swarmed the area. He could be in the woods, holed up in somebodys basement there could be a hostage situation. They are doing the fugitive investigation, conducting interviews, setting up surveillance. Reporter as the search heats up, this area is on high alert. I hope he gets captured so we can sleep at night again. Reporter at this hour, authorities in kentucky confirm that a sheriffs deputy spotted the suspect after he walked up to a home and asked for a ride. Then he ran away. They set up a perimeter and plan to work through the night. Gabe, thank you. We are back in a moment with good news if youre about to book a flight for the holidays. Look, the wolf was huffing and puffing. Like you do sometimes, grandpa . Well, when you have copd, it can be hard to breathe. It can be hard to get air out, which can make it hard to get air in. So i talked to my doctor. She said. Symbicort could help you breathe better, starting within 5 minutes. Symbicort doesnt replace a rescue inhaler for sudden symptoms. Symbicort helps provide significant improvement of your lung function. Symbicort is for copd, including chronic bronchitis and emphysema. It should not be taken more than twice a day. Symbicort contains formoterol. Medicines like formoterol increase the risk of death from asthma problems. Symbicort may increase your risk of lung infections, osteoporosis, and some eye problems. You should tell your doctor if you have a heart condition or high Blood Pressure before taking it. Symbicort could mean a day with better breathing. Watch out, piggies children giggle symbicort. Breathe better starting within 5 minutes. Call or go online to learn more about a free trial offer. If you cant afford your medication, dave, im sorry to interrupt. I gotta take a sick day tomorrow. Dads dont take sick days, dads take nyquil severe the nighttime, sniffling, sneezing, coughing, aching, fever, best sleep with a cold, medicine. What if one piece of kale could protect you from diabetes . What if one situp could prevent Heart Disease . One. Wishful thinking, right . But there is one step you can take to help prevent another serious disease. Pneumococcal pneumonia. If you are 50 or older, one dose of the prevnar 13 vaccine can help protect you from pneumococcal pneumonia, an illness that can cause coughing, chest pain, difficulty breathing, and may even put you in the hospital. Even if you have already been vaccinated with another pneumonia vaccine, prevnar 13 may help prevnar 13 is used in adults 50 and older to help prevent infections from 13 strains of the bacteria that cause pneumococcal pneumonia. You should not receive prevnar 13 if you have had a severe allergic reaction to the vaccine or its ingredients. If you have a weakened immune system, you may have a lower response to the vaccine. Common side effects were pain, redness or swelling at the injection site, limited arm movement, fatigue, headache, muscle or joint pain, less appetite, chills, or rash. Get this one done. Ask your doctor or pharmacist high drama caught on camera in peru. A skydiver left dangling underneath a plane when he went to jump and the leg of his suit got caught on the step. Unable to free himself, he hung upside down for nearly 30 minutes as the pilot flew in circles. He was finally able to reach a knife, cutting off part of his pants before falling, pulling his reserve chute and making a safe landing with just a cut on his hand. Good news if youre flying on the inside of the plane for the holidays. If you havent booked yet, wall street journal says no problem. Tickets for a lot of busy routes are reportedly getting cheaper this year. A round trip from San Francisco to las vegas is 33 lower than last year. From chicago to new york, the price is 26 lower. Here in california, powerful winds are whipping through the state in whats being called the first major santa ana wind event of the season. A red flag warning has been issued as winds spread. A blaze in Santa Barbara county, 70 acres and counting, more than 100 firefighters using everything they have, including a dc10 air tanker to get it under control. When we come back, the mystery why a Record Number of sharks are swimming closer to the west coast and why it may foretell a historic event yet to moderate to severe Crohns Disease is tough, but ive managed. Except that managing my symptoms was all i was doing. And when i finally told my doctor, he said humira is for adults like me who have tried other medications but still experience the symptoms of moderate to severe Crohns Disease. And that in clinical studies, the majority of patients on humira saw significant symptom relief. And many achieved remission. Humira can lower your ability to fight infections, including tuberculosis. Serious, sometimes fatal infections and cancers, including lymphoma, have happened; as have blood, liver, and nervous system problems, serious allergic reactions, and new or worsening heart failure. Before treatment, get tested for tb. Tell your doctor if youve been to areas where certain fungal infections are common, and if youve had tb, hepatitis b, are prone to infections, or have flulike symptoms or sores. Dont start humira if you have an infection. Ask your gastroenterologist about humira. With humira, remission is possible. You never know when itll be your moment to shine. So dont trust your smile to any regular toothpaste. Improved crest 3dtwhite brilliance removes 5 times morerstains than the red box. Try the whole collection for a if you could see your cough, its just a cough. Youd see how often you cough all day and so would everyone else. New robitussin 12 hour delivers fast, powerful cough relief that lasts up to twelve hours. New robitussin 12 hour cough relief. Because its never just a cough. This bale of hay cannot be controlled. When a wildfire raged through elkhorn ranch, the sudden loss of pasture became a serious problem for a family business. Faced with horses that needed feeding and a texas drought that sent hay prices soaring, the owners had to act fast. Thankfully, mary miller banks with chase for business. And with greater financial clarity and a relationship built for the unexpected, she could control her cash flow, and keep the ranch running. Chase for business. Finally tonight, a Record Number of sharks, many of them great whites are swimming here off the west coast. Researchers think they know why. As they tell Nbc News National CorrespondentMiguel Almaguer, the sheer number of these creatures may show el nino is already hitting the region. Reporter lurking in shallow waters just off the coast of southern california. That shark 3319 is within 500 yards of us right now. Reporter marine biologists are tracking a juvenile six foot great white shark. They are here off Huntington Beach in numbers scientists havent seen before. These predators for nearly a decade. The great whites may be an indicator el nino conditions are here and strengthened. Last two winters, none of the animals we tagged had migrated. We think that has to do with water temperature. Reporter even a slight rise in temperature means more food. More fish staying put. Researchers are teaming with Huntington Beach police. Within minutes we found our first great white shark. Hammer heads and great whites are close to shore. Though rarely aggressive, there have been encounters. This el nino has the potential, if it continues to build, to be a record breaker. Reporter experts say el nino will deliver storms, floods and mudslides that could alter our landscape. Already, the ecosystem in the ocean is changing. We get a whole new food chain that typically isnt part of southern californias ecosystem showing up during el nino. Reporter perhaps natures Early Warning system, as el nino builds. Miguel Miguel Almaguer nbc news, los angeles. That will do it for this thursday night. Im lester holt. For all of us at nbc news, thank you for watching and good