Begins right now. Announcer from nbc news World Headquarters in new york, this is nbc nightly news with lester holt. Good evening. Im Thomas Roberts in for lester tonight. We begin in california, where for the second day in a row, police and protesters clashed over the appearance of donald trump. Just south of san francisco, in burlingame, dozens of protesters stormed barricades confronting police in riot gear outside of a hotel where trump was scheduled to speak at the republican state convention. The clashes captured on live tv, forcing trumps security detail to an alternate route. Halle jackson has the late details. Reporter busting down barricades theyre breaking through the barrier, rushing into the front of the hyatt regency. Reporter donald trump appeared late this afternoon. Swarming the entrance, clashing with police in full riot gear. A scuffle with one trump backer trying to get in. Its a revolution. Its come to violence. Reporter trump and his security detail forced to ditch their cars and hop a highway barrier over a berm into the back. That was not the easiest entrance ive ever made. Felt like i was crossing the border, actually. I was crossing the border. But i got here. Reporter more chaos in california, after this, less than 24 hours ago in orange county. A demonstrator stomping a police car, a Trump Supporters bloodied after witnesses witness a confrontation. Nearly 20 people arrested. The controversial candidate today unfazed by the protest outside, snapping pictures inside with california republicans. So heres the Washington Post today. The time has come to admit that Republican Voters want donald trump. Reporter the tense protests, not unusual at trump events, probably wont stop if he ends up in a fight this fall with hillary clinton. And in california, trump could wrap up the nomination june 7th. In the liberalleaning state, hes unsurprisingly unpopular overall, but among conservatives, a slim majority view him favorably. When i focus on hillary, shell go down easier than any of the people we just beat. Reporter his remarks over, trump ready to leave the same way he came in. Ted cruz, meanwhile, making his case for the nomination in indiana. A makeorbreak state for him. Picking up kind of an endorsement from governor mike pence. Pence praised trump, too, the sign the Never Trump Movement may not have the power it needs to stop the frontrunner. Halle, thanks so much. Sunday on meet the press, chuck todd sits down with senator ted cruz and his game plan from 48 hours from his last stand in indiana. There is developing news from the cdc. The first death linked to the zika virus on u. S. Territory in puerto rico. The victim was an elderly man. Raising new concerns as we learn of a new test to detect it. Nbcs tom costello has the details. Reporter its ground zero in americas fight against zika. Now the first death reported in puerto rico. A 70yearold man who died of internal bleeding. Zika is most commonly connected to guillainbarre syndrome. Since november, 707 confirmed zika cases in puerto rico, 89 of them pregnant women. Thousands more are expected to become infected there, and potentially on the u. S. Mainland. But in congress, republicans still arent approving emergency zika funding. If you look at the continental United States, were still getting more and more what we call travel related cases, people who are infected elsewhere, south america, central america, or the caribbean, who get infected there and then come back to the United States. Reporter babies born with microselfy have unusually small heads and brains. In seattle, stephanie and andre silva decided not to take a chance, after becoming pregnant while living in brazil, they returned home, then waited for weeks for a zika blood test to come back from the cdc. It was very scary. It was very scary, and your mind goes everywhere, to all the worst case scenarios, and you just you think way too much. Reporter it took a full month before she learned she was zikafree. The fda approved local labs to run zika tests, reduce the backlog and anxiety. An obgyn is telling pregnant patients to get tested if theyve already returned from zika zones. Im telling them to if they are having intercourse with somebody who may have been infected, either not to have intercourse with those people or to use condoms. Very, very important. Reporter the good news . Even if a pregnant woman contracts zika, her unborn baby may not. Once again, today researchers stress that for women who contract zika and are not pregnant, and dont get pregnant for eight weeks, future pregnancies should not be at risk. Thomas . Tom costello, thank you. We turn our attention now to the severe threats for tens of millions as we head into this weekend. We have new tornadoes already tonight firing up, and hail the sides of soft balls. It is a dangerous mix. Miguel almaguer is in one of the target areas for us tonight in dallas. Repo reporter battered. And tonight in oklahoma, yet another round. Lightning, hail, and possible tornadoes. 25 Million People in the plains facing a Severe Weather warning. Parts of oklahoma, louisiana, texas, and arkansas on the alert for flash flooding. Tonight in northern texas, a series of storms developing. The forecast predicting even more this weekend. Severe storms today could bring hail, damaging wind and tornadoes. Tomorrow we watch a lot of the same areas and heavy rain could bring flooding. Reporter in houston, where earlier this month, more than 1,000 homes were flooded, tonight theyre getting ready for more water rescues. And in colorado, theyre not done with the snow. Six inches in the forecast. Guarantee for slick roads. From central california, to india indiana, this week 27 tornadoes in ten states. Now a new weekend warning for the south, getting ready for dangerous days ahead. Tonight here in dallas, where its warm, humid, we have seen some rain. The sky looks ominous. In this area, there have been reports of golf ballsized hail and tornado warnings. Its the start of what could be a dangerous few days ahead. Thomas . Miguel almaguer. As Police Follow the trail to track down the source of the powerful painkillers that were found as nbc news has reported on the singer. And on his property. Nbcs Stephanie Gosk has the very latest. Reporter within hours of princes death, the carver countys Sheriffs Office served a search warrant for paisley park. They say prescription painkillers were found on princes body, and in the house. Where the drugs came from, and who prescribed them, are a key part of this case. A source connected to the family tells nbc news that one of princes doctors was a close family friend. Records released by the Sheriffs Office show that the 911 call on april 21st was not the first call for help. Two times last year, august and september, authorities were contacted for unspecified medical reasons. Still waiting for answers about his death, princes family has already started to discuss the estate. With no will, spouse or children, the estimated 300 million will be split among siblings, including his half brother Alfred Jackson who hadnt seen prince in years. How was it to see everybody . Pretty good. It made me feel a lot better. Reporter outside paisley park, a painter touches up a portrait, more interested in paying tribute to princes life han in the investigation of his death. Stephanie gosk, nbc news, minnesota. Its unlike anything nfl fans have seen before. Right before the draft began last night, someone posted an incriminating video of a player many thought would be one of the top picks. And it came from his own account. He said he was hacked. As blake mccoy reports, it sent his fortunes tumbling. Reporter just minutes before the nfl draft last night, a stunning revelation that cost a top prospect millions. This video showing laramie tuns il smoking a bong with a gas mask posted to his own twitter account. The draft night drama sending him tumbling to the number 13 pick, well below what had been expected, costing him at least 8 million. Fans surprised. Tunsill forced to apologize. I made a huge mistake. Things happen. I cant control things, who gets in my phone and hacking my instagram, twitter. The Miami Dolphins select lar my tussill. Reporter the dolphins claim they already knew about the video. Were very comfortable with the player and the person. Reporter tensill said he doesnt know who hacked his account just before the draft. But speculation is swirling around his stepfather. The two have been involved in a nasty legal battle, that stepfather telling tmz today it wasnt him. On his instagram, another post. Text messages of tunsill asking athletic officials at old miss for rent money, money he admits receiving, a violation of ncaa rules. The school is investigating. By 9 00 last night, he was the most famous College Football player in america. It just happened to be for all the wrong reasons. Reporter down, but not out. Im drafted in the nfl. So im happy. Reporter the Miami Dolphins giving him a second chance. Blake mccoy, nbc news, chicago. Another dangerously Close Encounter between the u. S. And Russian Forces over the baltic sea. And it comes just weeks after russian jets were caught on this video buzzing a u. S. Warship. In the latest incident, for the second time this month, military Officials Say a russian jet did a barrel roll over a u. S. Plane coming within 25 feet. 16 u. S. Military personnel have been disciplined for the deadly air strike on a Doctors Without Borders hospital in afghanistan, but the pentagon says it was not a war crime. And none involved Face Criminal Charges for the october 3rd attack. When a u. S. Gun ship fired 211 shells for 30 minutes, it killed dozens of doctors and patients there. Investigators are now blaming human errors, fatigue and equipment failure for the mistaken attack. A meeting at the vatican today between Vice President biden and pope francis. The Vice President was there to speak at a conference about the cancer moon shot plan hes leading in a search for a cure. The pope and Vice President took a few moments to greet each other, as the people there looked on. Still ahead for you tonight, the new will ferrell movie about president reagans battle with alzheimer alzheimers, sparking a firestorm before the cameras even role. The end to an era for one of the my mom loves giving me advice. She even gives me advice. About my toothpaste and mouthwash. But shes a dentist so. I kind of have to listen. She said jen, go pro with crest prohealth advanced. Advance to healthier gums. And stronger teeth from day one. Using crest toothpaste and mouthwash makes my. Whole mouth feel awesome. And my teeth are stronger too. Crestpro health advanced. Is superior to colgate total. In these 5 areas dentists check. This check up . So good. Go pro with crest prohealth advanced. Moms right. Again her long day as anne. Hair stylist starts with shoulder pain when. Hey joanne, want to trade the all day relief of 2 aleve with 6 tylenol . Give up my 2 aleve for 6 tylenol . No thanks. For me. Its aleve. 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Call your doctor if you have muscle pain or weakness; feel unusually tired; have loss of appetite, upper belly pain, dark urine or yellowing of skin or eyes. These could be signs of serious side effects. Ask for the crestor 3 card. Ask your doctor about crestor. Back now with the major backlash over a Hollywood Comedy planned about Ronald Reagan in the grip of alzheimers with the actor will ferrell, portraying the former president. Reagans family is outraged saying it is no laughing matter. Chances are the families of the more than 5 million americans who suffer from this disease might agree. We get details from nbcs cynthia mcfadden. Reporter theres no denying will ferrell is a funny guy. Im entering the race for president of the United States of america. Reporter and he has mocked president s before. Youve got to admit its a pretty good plot twist that i turned out to be the smart one. Reporter but is it going too far to play president Ronald Reagan with alzheimers in a new comedy. Ronald and Nancy Reagans daughter, patty davis, said emphatically yes. In an open letter to farrell thursday, davis wrote, i watched as fear invaded my fathers eyes, this man who was never afraid of anything. I heard his voice tremble as he stood in the living room and said, i dont know where i am. The films premise is this. That reagan suffers dementia symptoms in his second term, and a white house intern has to convince reagan he is an actor playing the president. In 1995, president reagan was wildly lauded when he helped teach the nation about alzheimers, in his open letter to the american people. I now begin the jourpy that will lead me into the sunset of my life. I know that for america, there will always be a bright dawn ahead. People arent flocking to the movie theaters to watch something funny on alzheimers. Reporter joe is the new director of the hollywood reporter. If you combine alzheimers which isnt a funny topic, and then combine the president much the United States that the Republican Party adores so much, Ronald Reagan, its really a recipe for disaster. Reporter in her letter, davis suggested ferrell visit a dementia facility as she has. I didnt find anything comedic there, and my hope would be that if youre a decent human being, you wouldnt either. And tonight will ferrell backing out. His representative saying, he is not pursuing this project. Cynthia mcfadden, nbc news, new york. Well be back in a moment with what sparked of the social media feud today between the obamas and the royals. Why do some cash back cards keep throwing obstacles at you . First they limit where you earn bonus cash back. Then those places change every few months . I think ill pass. Quicksilver from capital one puts nothing in your way. You simply earn unlimited 1. 5 cash back on every purchase, everywhere. You cant dodge the question. Whats in your wallet . 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Enjoy the relief. This weekend marks the end of an era for the ringling brothers and barnum and bailey service. Ring ling is retiring its famous elephant act and sending them to a florida conservation. Nbcs Kerry Sanders explains why this show must not go on. Reporter kids are still captivated at the sight of an elephant. But now after 145 years, performing at the ringling brothers and barnum and bailey service, the tradition is coming to an end. Animal activists said it was cruel to force elephants to perform. And changed local laws. Its very hard to operate when were touring week in and week out, and in every city the rules and the regulations and the guidelines are different. Youre a good looking girl. Reporter in all, 40 performing elephants will retire to florida, at ringlings center for elephant conservatioconservati, a 200acre preserve that is not an attraction open to the public. What is an elephant retirement . This, trees, people, relationships, other elephants, plenty to eat. Pedicures. Really, its pretty much going to be like their life on the show but without traveling. Reporter the elephants will still be working. We have cells reporter researchers in utah are searching for clues in the circus elephants blood. They want to know why elephants rarely get cancer, and if that could help pediatric patients. This weekend, a final curtain call at the greatest show on earth. Kerry sanders, nbc news, providence, rhode island. Its one of the most powerful machines on the planet. A 17milelong super conductor worth 7 billion designed to slam particles together at nearly the speed of light. And tonight its been knocked out of commission by a tiny animal officials at the lab in switzerland say theyre experiencing severe electrical problems, and theyre pretty sure its because a weasel chewed through some of the wires. And it could take weeks to fix. Now in a moment that sent fans of the west wing into a frenzy. Allison as White House Press secretary c. J. Craig on the longrunning hit tv show actually appeared in the White House Briefing room in character. She was there to discuss a serious issue, the Opioid Epidemic in america and those helping to fight it. You dont see this every day, Queen Elizabeth trash talking the president and first lady. It was all in jest, of course. The obamas first got it started. They tweeted a video tweeting prince harry about the u. S. Bringing it to a competition for wounded veterans. Harry tweeted back with some help from grandma. Careful what you wish for. Oh, really . Boom. I think harry wins. Were going to see who wins those bragging rights, though, when the invictis games happen in florida. They begin on may the 8th. When we come back, its a house divided. A couple married for 35 great years, then along came d look, the wolf was huffing and puffing. Like you do sometimes, grandpa . 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Reporter shes a lawyer, john a doctor. Two peas in a pod. Except when it comes to one president ial candidate, donald trump. I dont get the interrupting. He handles a lot of criticism. Thin skinned. Reporter you may have gathered john is committed. Hes serious. He wants to get things done. Reporter janine hasnt picked a candidate, but said it aint going to be the donald. I dont know who he really is politically. Reporter things were heating up. We have different reactions when donald trump is talking. Reporter where rules are needed, and fast. Separate political viewing on two tvs. And only in the living room. No donald in the bedroom . No donald in the bedroom. Reporter a safe word to stop the sniping when things boiled over. Sometimes he likes to say it after you said five other things. Like i cant refer. He referred to you earlier, he said, i think shes coming around to my point of view. Really . Really . What would you base that on . Your intelligence. I think my points are better. Im waiting for him to say, she gets emotional. Im going to say foliage right now. Reporter still, with the election 27 weeks away, the hinmans vow they wont let politics interfere with the state of their union. Kevin tibbles, nbc news, fresno. Referees have a lot of work this season. Thats going to do it for us tonight. Im Thomas Roberts here in new york in for lter. Es ready, set, run ten miles. I run because i want to tackle this. 40,000 runners in all, each with a personal story to share. Im afraid. Im really afraid that im not going to finish. Meet gina. Shes beaten the odds. Why running sunday means so much to her. But before you can beat broad, you need that bib. Very exciting. Were at the expo with the hottest items for runners. Also, a running expert explains what to know before leaving your house sunday morning. Lace them up. Were ready to run. Are you ready . Good evening. Jim jim rosenfield. Im jacqueline london. The run starts in 37 hours. The expo ended for tomorrow. Tomorrow, there is time to pick up your bibs if you are running. Tim furlong ran into runners down at the expo today. He asked them about running in the rain. Reporter 40,000 runners have wait aid ye wait aid year. Its a fabulous race. The crowds are wonderful