vaccination regimen for children of that age group, namely six months to four years plus up to five will be a three-dose regimen. what had happened is that it was hopeful that a two-dose regimen would be able to do it. as the data began coming in, it became clear that they wanted to continue with the three-dose study before making any determination about the efficacy. there's no doubt about the safety. the one thing you don't want to confuse parents is they think there's something here that -- there's a concern about safety. it's not a safety concern. they're accumulating data rapidly on the three-dose regimen. that will be presented to the fda, the fda will do what they usually do, scrutinize it carefully and then make a determination as to what the recommendation is, what dose and what dose regimen.