Presshere. Good morning. Im scott mcgrew. Weve grown accustomed to people changing the world. Steve jobs and the iphone, elon musk with all kinds of things. Musk says he wants to go to mars and i have no doubt that he will. But here is priscilla announcing that she and her husband Mark Zuckerberg will stop disease. By investing in science today, we hope to build a future in which all of our children can live long and rewarding lives. We set a goal. Can we all together work to cure, prevent or manage all disease within our childrens lifetime . Chan, a pediatrician, wiping away tears as she talks about the children she could not save in the past. There is a laboratory in San Francisco on the ucsf hospital campus where scientists right now are bringing an end to the disease. Its a staggering goal. They put a doctor in charge of the grant and hes made himself who has made great headway in fighting malaria and asthma. Hes copresident at the Chan Zuckerberg bio hub. Let me start with this concept of stopping, managing or preventing disease. It doesnt seem possible. I agree. Its an incredibly bold vision to cure, manage or prevent all diseases in our childrens lifetime seems like an audacious goal. But you have to remember that the way lifec span is going no thats probably about 100 years. If we think about what science was 100 years ago, 1917, what we didnt know and what we know now and the amazing advances that have been made, theres no way that you can predict what 100 years if someone said we are going to the moon, you would have looked like a lunatic. You would have sound insane. Absolutely. But youre not casting that wide of a net to begin with, right . Youve chosen what you are going to focus on and how have you made those decisions . The Chan Zuckerberg bio hub is one Small Initiative being executed by Mark Zuckerberg and priscilla chan. Its joining together three powerhouse universities that we have here, uc berkeley, stanford and uc San Francisco, to bring forth new tools and developments that is going to actually deliver on the promise of managing, curing and preventing diseases in our childrens lifetime. This is very serious here. Lets look at that analogy. Instead of building the golden gate bridge, when they said, hey, were going to go to the moon, back to the moon analogy again, we dont have the math. We dont have the materials or the knowledge of doing this. We literally have to build the tools to build the rocket first. Is that where you are . Your scientists are not trying to cure cancer. They are trying to build the tools that will cure cancer. Is that accurate . Well, its not inaccurate. We are focusing on new innovations and Technology Development and were trying to translate it into action at the bedside or future bedside. So were trying to do point a to b. So for Mark Zuckerberg, does he bring the organizational oommph that youre doing that creates another task . Absolutely. I think both priscilla and marks energy are inspiring the bio hub. What youve just said is correct. You do an experiment, doesnt work out, make the next one better than that. The bio hub is a tenyear experiment that will be it rated on and developed and pro tellpe forward. This may be a bad comparison but zuckerberg will roll out something that initially consumers may not like but eventually they will get it right. So its kind of trial by error and im saying on a different scale its happening with your organization. The bio hub is an experiment in bringing together three universities who work in an ad hoc way well together but not in a systematic way together. Joe, walk me through. You have these scientists, and 40 of them got grants. Is that right . Weve awarded 47 investigatorships. And they have their own labs. And you are going to cure cancer, youre going to cure malaria, youre in charge of how do you tell 47 incredibly smart people what and whats your role . How do you manage it . You dont tell them what to do. You give them money in a lab and they make amazing things. But then what is your job . The process, first to get to your point, is not scrutinizing what their detail projects are. Thats not about this process. Were taking bets on human capital. Were trying to identify outstanding individuals in our Research Community and were placing bets on them. But not telling them what to do. These investigators are totally discretionary. Do your best science. We believe in you. Is there an overlap with the bill and Melinda Gates foundation . They are looking for the cure to malaria, at least preventive. So we work very closely with many other foundations, including bill and Melinda Gates foundation. They work in a different way. Its a different kind. They are focused on Global Implementation in the prevention of malaria, which is near and dear to my heart as well. I think were highly complementary. Were going to take a quick break but well be right back in just a moment. My wife called and told me that her water broke and between the excitement of that and also dealing with this, my only response was, okay. Press here is available on come past. Welcome back. Were talking to joe from the bio hub. Where are you guys making the most headway in all of the projects going on . Were only six or seven months old. Weve managed to attract some amazing talent to the bay area. So were actually hiring some outstanding talented young investigators, early career investigators that have amazing new ideas and thats been part of it, is actually tracking great talent to the bay area in the life sciences. And so its an early goal but i think were making great headway. Is one of the novel things about this, the way that youre organized with the sharing of information and collaboration. Weve been hearing more and more of these efforts. Is that something as unprecedented as its been made out to be . Its one of the major goals of the bio hub experiment. Can you have an entity that brings powerhouse institutions that have their own turf and egos to bring them together to a common goal and Work Together in a highly collaborative fashion. Isnt that what science is supposed to be, though . Is it private companies and Drug Companies that have closed things off . Where did we lose this fact that scientists should be sharing information and collaboratively or is it human nature, im not going to tell you . Theres many answers to that questions. One of the things that has historically prevented sharing is the public sharing of our science was often held by corporations in perpetuity. That is, if a Family Member is suffering from a disease, you may face a pay wall, have to pay to see that article. Were involved in getting information into the public and other researchers hands without pay walls as fast as possible to accelerate the pace of research. Its interesting what youre trying to do is so ambitious and one of the criticisms is that it solves small problems. We mentioned the iphone at the beginning but its become a fact that you can have something delivered to your home. I think does that appeal to somebody like, again, zuckerberg or bill gates that will have lasting impacts . Theres no question that Mark Zuckerberg and dr. Chan have extremely ambitious longterm goals. They are not in it for the next year, next two years, next product cycle. They are in it for the next century and that is the scale and distance. To remind the viewer of what were talking about, the bio hub is where they want to cure, prevent or manage all diseases. Not just heart attacks but all diseases. Youre a smart guy. When they came to you and said we want to put you in charge of this, i think id still be intimidated. You say all disease. How about 75 of diseases. Its a shocking goal and took me back but think about it, what did we know 100 years ago . How far have we come and how fast are we learning now . Even ten years ago, no one even had a clue what genome editing is. Im sure youve heard about it on the show. And now that revolutionizing everything that we do, making things possible that we didnt even think were possible ten years ago. You extrapolate 100 sure. And i imagine that helps attract amazing people to part of our goal is to attract the top mibnds, hottest talent in the field. Is this something that maybe is the most easily obtained it sounds stupid. But the most easily obtained things to cure . I dont think you can necessarily cherry pick and say theres low hanging pick in the disease world. Theres always a counterargument about why something is so important. But were closer to solving or preventing than others perhaps . I dont know. You know, we just mentioned the revolution of genome editing. Its the ability to cure single gene defects in people. You can think about sickle cell anemia. Thats an obvious one. And this new technology, which we didnt even conceive of or have an understanding of ten years ago, its most assuredly going to cure that disease. There are many diseases that call into that category and one at a time they will be knocked down. As the Technology Accelerates and gets faster, i anticipate the spread of disease that becomes attractable only to go faster. Its my understanding that dr. Chan and zuckerberg gave you 50 million to develop this center . It was funded at 600 million. Not sure where i got 50 million. Is that enough . What number is the right number for curing all of the disease . Bio hub is a small experiment in a larger portfolio. The Chan Zuckerberg is a variety of other philanthropic efforts. Were one small subcomponent and only a tenyear experiment. I guess my question is, if somebody came to me and said, i want you to build this bridge, id go over the numbers and say, all right, my numbers are going to be x. I want you to cure all disease, stop all disease, theres no number. How could there be a number . 6 million, 60 million, it doesnt make a difference. I dont think its useful to imagine what that number would be. It could have such a major impact that you cant calculate what its value would be. What is the you got involved in this after a number of different things. You did it was an attempt to have a ship understand what disease somebody has, which kind of reminds me of the theranos thing. Well get to that in a second. Where did you come from and what landed your interests other than the huge challenge of this . So im a professor at utsf and my interest is infectious disease. Half my lab works on malaria and the other half on diagnosing unknown infections and we do that by technological tool developments. Doctors throw up their hands, we have no idea what it is, we try to figure out what is wrong with somebody to hopefully cure them and we have actually done that in many cases. Youre like dr. House. Were dr. House with data. Not intuition. Have you tried the mouse fights . This is the copresident of the Chan Zuckerberg bio hub. Please know youll be a welcome guest. I cant imagine a bigger attempt. Thank you for being here. Thank you for having me into well, now we pivot to cute cat videos when press here continues. Press here is available as a podcast on itunes. Welcome back to press here. I assume you know what a jif is even if you dont know it by name. If it doesnt sound familiar, let me remind you. They are looping videos, almost always lowquality video. People post them to twitter or send them to each other in text messages. Theres a whole section of i messages on your iphone dedicated to this. The most talked about recently is the trump versus cnn jif that the president posted to his own twitter account. President obama has had his own controversy with gif. Thats the way its spelled, gif. Youve made up your mind that its gif . Yes. An online gif resource, lets start with how do you the burning question. Is it gif or jif . So, the creator called it gif. We call it jif. President obama is entirely wrong. Let me start with this. Gifs, as i remember, started back when we could barely transmit video over the internet. You had these low frame rate, lowquality videos and yet were still using them. When the age of computers game, we putc typewriters on t pc and that was fine. And then we took the querty keyboard and put it on the phone and instead it was so bad for what were trying to achieve, its an easy way for you to transmission your thoughts and ideas and the person youre conversing with. Its kind of like their own language. For instance, i have two daughters. One of them likes gifs with dogs and another with drake. She loves those. Is it a way of communication between people . It is. You can imagine like when you take a piece of content and you just look at the visual element and the time element and remove the sound element, then people can interpret that content in many, many different ways. So your emotional attachment to that piece of content becomes the reason why you want to share and talk about it. And that create as new way for people to talk about. It really is interesting that its become a new mode of communication, to go back to our president s recent gif and that he tweeted out. This is an expression and saying which hes said in many other ways as well. Is that totally New Territory . So i think our current president is an amazing piece of content for all were trying to do. Like the campaign has started. Its been amazing content after amazing content that people want to share and discuss. Our content is being shared on a lot of different publications. They are all embedding our content and talking about it because all these facial expressions that are given day after day. So trump should use more gifs because he doesnt have to type anything. Cnn was the first one. He may have just now discovered gifs. Maybe were entering a whole new realm. Let me ask you, richard, oh, the new yor times mathe new yo content. How do you make money . We wanted people to come and create content and then they share it and the ones that become viral are the ones that basically people like and share, et cetera. Because people are sharing widely on all of these articles and magazines and publishers, thats created a lot of con tebt f content for us all through the power of these gifs and through advertising. You turn the video into a gif for me. And youre selling banner ads, i assume . Yes. Over time, thats what we will do. Although, weve been very focused on goat. So you dont make any money . Were not making any money. But people are attracted to these pages. There will be banner ads that people can also look at and get value out of them. Whats your favorite gif . So, you know, until recently, it was so at the induction of the president , Hillary Clinton gave him a nasty look and somebody recorded it with the cell phone and shared it. Its an amazing piece of content. Wow. What make as good one . If im going to sit down and say, all right, this is where i want to go viral. First of all, probably cant, but what makes a good gif . So there are two things that are really important when it comes to gifs. The first one is the time element. You want the immediate attention, like the first couple of milliseconds has to be something very colorful that will attract your attention. Thats very important. And anything that has a lot of motion in it is what gets people excited about it. So thats why trump is so interesting because theres so much happening. Ee the people they are showing and the way they react, right . Right. Is there a celebrity here, male or female, an animal that is the number one gif . Yes. There are millions and millions of views. Wow. Is it still super popular . Yes, like with the younger audience. Cats created the internet. Not al gore. A lot of times cats because of all the different emotions that are recorded a that can be shared, people use animals as an easy way to express either i like you or i hate you. What weve learned today is that drake gifts are popular and cats either like you or hate you. That i already new. Richard is the head of giffy. We appreciate you being with us. Thank you so much for having me. Press here will be back in just a minute. Press here is available as a podcast on itunes. Thats our show for this week. If you missed the top of it, there are lots of interviews that you can watch, including this weeks at presshere. Com. Im scott mcgrew. Thank you for making us part of your sunday morning. Press here is sponsored in part by Barracuda Network and storage solutions. Comunidad del valle. Im damian trujillo, and today, celebrating 50 years at cet, and theyre having a bash, on your comunidad del valle. Male announcer nbc bay area presents comunidad del valle with damian trujillo. Damian well, we begin today with the monthly visit by the Mexican Consulate in san jose. With me once again is the consul general of mexico in san jose, embajador mauricio toussaint. Welcome to this show, welcome back. Mauricio toussaint thank you, thank you, damian, and its a pleasure as always to be here in comunidad del valle. Damian its always good to have you back. First of all, talk about your title because youre the consul general, but we all call you embajador. Tell us why we call you embajador. Mauricio well, itsthe thing is my rank in the Foreign Service is ambassador. But my post is consul general in san jose