News World Headquarters in new york, this is nbc nightly news with lester holt. Good evening. Another day of desperation in the south, where historically high floodwaters continue to rise in texas. The death toll has now climbed to six, after severe storms dropped over a foot of rain in parts of houston. Virtually paralyzing the nations fourth largest city. Dozens more had to be rescued and evacuated today as nine texas counties remain under a state of emergency. We begin tonight with nbcs Janet Shamlian in one of the hardest hit communities. Reporter a day of dramatic rescues after Cypress Creek roads overnight filling into homes and lives. We have two dogs. Reporter this family leaving everything behind. There we go. Reporter the only way out, on an air boat with the Harris County sheriff. How was it to leave your house . It was very hard. I dont know. It just keeps coming in. Reporter they dont even know where theyll spend the night. Im frightened. I dont know when ill be back at home. I dont know when ill be back at school. Reporter we rode along as deputies answered call after call. Ive been out here almost 35 years and never seen water this high. Reporter in every direction, water, and the people whose lives it uprooted. What now for your family . Honestly, i dont know. Reporter dozens of seniors with wheelchairs and walkers rescued from their homes. An assisted living center. Less than a year after a major flood swept the city, people seeing their belongings destroyed a second time. Weve got to start all over again. Reporter houston is built over bayous. That overflow during heavy rainfall. The city is flat, mostly concrete, with clay soil, leaving nowhere for the water to go. 240 billion gallons fell on the ground this time. But its the smaller number thats more impactful. At least six people died in the storm. Among the victims, a mom of three. We spoke to her husband as the floodwaters rose. She called me and she told me shes in trouble. Water all around. Reporter back here at Cypress Creek, you can see its completely overspilled its banks. Its flowing across a major artery in the houston area into these businesses, and the neighborhoods behind me. It will be a long cleanup for many families here in the houston area. Lester, back to you. Stunning view. Janet, thank you. Time is running out to rescue survivors still trapped in the rubble from the massive earthquake in ecuador. Its been nearly three days now, and even as some are found alive, the death toll is mounting to nearly 500 dead. Nbcs Miguel Almaguer is there with a never before seen look at the devastation. Reporter nearly every perspective, the coastal city is in ruins. 800 buildings are destroyed. Many more are on the brink of collapse. The search for survivors is painstakingly slow. Daisy gonzalez has been here since saturday. Her brother, victor, is missing inside the miami hotel. This is what it used to look like. Now rescue teams tell us 50 people are inside. The anguish on the faces is as clear as the destruction. Families keep vigil just a few feet away. This 9yearold girl and her 1yearold sister waiting for news of their injured mother who was rushed away in an ambulance. They tell volunteers theyre scared. They just want to go home. While rescue teams are on the ground here from eight different countries, many say not enough is being done. Neighborhoods are decimated, countless are missing, and many buildings have not yet been checked. But this is what gives so many hope. A hotel worker buried for two days, uses his cell phone to signal rescue teams. Hes weak, but will survive. Women and children are found alive, and pulled from the rubble every day. But too often, the news is grim. At the miami hotel, theyve discovered more bodies. Daisy learns her brother victor is gone. Still, she stays. Its too hard to walk away and say goodbye. The 7. 8 quake took only seconds to destroy this neighborhood, but the president says it could cost billions of dollars to repair all of the damage. Lester . Miguel almaguer, thank you. Its primary day in new york. Rich delegate hauls up for grabs for both republicans and democrats. For both frontrunners, trump and clinton, the aim is not just to win, but win big. Hillary clinton, doubledigit win could strip a dogged and determined Bernie Sanders of any claim of momentum. While for donald trump, a wide victory margin could put him on an easier track to clinch the nomination before the summers convention. Lets get the very latest starting with katy tur and the republican contest. Katy . Reporter good evening, lester. The campaign is expecting to win big here tonight. The next two weeks are crucial. Donald trump needs to win by a wide margin across the northeast before he gets to indiana. A wild card state where a loss could lead to a contested convention. Donald trump casting a ballot in new york city. Just a great honor. I think its a great honor for new york. Reporter looking at what could be a clean sweep in the empire state. Winning all 95 delegates. But the campaign is already looking ahead, focusing on the 54 unbound delegates in pennsylvania. Many of whom tell nbc news trumps team was the first to reach out. The northeast a sweet spot for trump where polling has him ahead by wide margins. Go to western pennsylvania and you see the jobs that have been lost. All that industry thats been shipped abroad. You know, i think were the only ones speaking to that message. Reporter prospects look good for the frontrunner, while ted cruz and john kasich are just hoping to pick off delegates in the blue corner of the country, setting up a showdown in indiana on may 3rd. Right now, trump needs 61 of the remaining delegates to clinch the nomination, but if he sweeps new york and wins big on the april 26th primaries, hell only need 50 to 53 . While ted cruz would find it mathematically impossible to win in anything but a contested convention. They are trying to deprive trump of the delegates he needs to secure the nomination, so they will go to an open convention where all bets would be off. Reporter working in trumps favor right now, a closeddoor campaign sheiakeup that has trump doing fewer interviews and giving shorter, more focused stumps. The goal, nbc news has learned, to hit key issues and minimize unforced errors. Katy tur, nbc news, new york. Im Andrea Mitchell in new york. No secret about the votes of that chappaqua couple. Hillary clinton confident of the state that made her senator twice will deliver a big win tonight. I hope everybody gets out to vote. Reporter but what is victory in her fight with bernie sande sanders . Polls are predicting a doubledigit clinton win, which could expand her lead over sanders by 25 delegates. But if she wins by only single digits, sanders out greeting crowds in midtown manhattan today could claim momentum by beating expectations. I think were going to do just fine. Reporter the sanders team has poured resources in new york, outspending clinton 21 on tv ads. Washington politicians are paid over 200,000 an hour for speeches. Reporter putting on those massive rallies. Its all taken its toll on clinton. Her favorability rating down 11 points since march. Partly because of the new york slugfest says the clinton team. He has leveled character attacks against hillary clinton. He has basically called her corrupt. Reporter and what if sanders loses big tonight. If a series of very big states go her way, what then would happen . Well, i think if you look at the math, no ones going to arrive at the convention with enough pledged delegates to secure the nomination. Reporter sanders was already looking past new york to the next contest in pennsylvania. I think were going to win here in pennsylvania next week. Reporter and despite all of the infighting, in exit polls only 13 of new york democrats voting today said that they would definitely not vote for clinton if she becomes the nominee. Lester . Andrea mitchell in new york, thank you. A Major Court Ruling tonight in the hotly contested issue, a federal court has sided with a transgender teen who is fighting to use the boys bathroom at his school in virginia. Its a case that could have implications all the way to north carolina, which has been the focus of intense debate over its socalled bathroom law. Our justice correspondent Pete Williams has late details. Reporter in the first ruling of its kind, a federal Appeals Court says its sex discrimination to bar students from using the restroom that matches their gender identity. Its a victory for a Virginia High School student gavin grimm who was born a girl, but identifies as male, and has undergone hormone therapy. The Appeals Court upheld u. S. Education Department Regulations that require Public Schools to treat transgender students consistent with their gender identity. The ruling applies to four other Eastern States that are in the same federal judicial circuit, including north carolina. So it likely means that states controversial transgender bathroom law passed last month this is hate and bigotry. Reporter cannot be enforced in Public Schools, including colleges and universities. North carolinas governor is asking his States Lawyers to study the ruling. This is a major, major change in social norms. That is going to be news to not only north carolina, but the 27 other states that dont allow this at this point in time. Reporter this was a 21 ruling by a threejudge panel. The dissenting judge said it tramples on all universally accepted protections of privacy and safety based on anatomical differences between the sexes. Lester . All right. Pete, thanks. The white house is condemning a major attack by the taliban in afghanistan. At least 28 people are dead, and over 300 more were injured when militants stormed an Afghan GovernmentSecurity Agency in kabul with a barrage of gunfire, after detonating a car bomb. Most of the victims were civilians, including children. The fda is launching a targeted campaign aimed at teenagers. The message, smokeless tobacco can kill you or lead to lifechanging deformities. Think about this, oral and throat cancer kills roughly one person every hour, 24 hours a day. Nbcs tom costello has the details on the blunt warning. Reporter from the rodeo to the Pitchers Mound its a young mans rite of passage in much of the country. But chewing tobacco, or dip, has been linked to gum disease, tooth loss and multiple cancers. Now the fda is targeting white boys in Rural America with a jarring message. When you believe a can of dip could do no harm. Dip can cause mouth cancer. Smokeless doesnt mean harmless. Reporter graphic images meant to scare the very teens who might feel invisible. It can cause mouth cancer. Reporter but breaking through is a challenge. That mark left by a can of chew in a back pocket is as much a part of the culture as Country Music in many states. These kids walk around seeing some of the most important people in their lives using dip, or chew, whether its their dads or their grandfathers, older brothers, community leaders. So they say to themselves, theyre all using it, so it must be okay to do. Reporter and every day, nearly 1,000 teenage boys are trying chew for the first time. Nearly as many as are smoking their first cigarette every day. Despite some of baseballs legends dying from oral cancers, as many as a third of Major League Players still chew. Now cities across the country are banning chewing tobacco in their ballparks. Former red sox pitcher Curt Schilling diagnosed with mouth cancer. I met men with half a face, half a town, half a jaw who tried to warn me. Reporter the hope, that todays teenage boys will listen. Tom costello, nbc news, washington. Still ahead tonight, surviving a stroke. The revolutionary new treatment thats been shown to eliminate lifealtering complications if patients get it quickly. Well tell you more on that. Also, a mother off to an earlymorning workout found murdered inside a church. Now the hunt is on for a suspect caught on camera, dressed in what is described as s. W. A. T. Style gear. Were back now with an amazing advance in treating the most common form of stroke. Every year, nearly 700,000 americans suffer a stroke caused by a blood clot. Survivors can be left with severely debilitating aftereffects. But nbcs rehema ellis looks at a new treatment that can leave stroke patients with little or no complications. Reporter steffan was driving to work one day when he started losing feeling on his left side. I rubbed my neck and i felt like i had a bruise. Within seconds, i felt like i was going to pass out. Thats when i had my stroke. Reporter the 43yearold was rushed to the hospital, where doctors gave him a clotbusting drug, and a groundbreaking new stroke treatment called a stint retriever. Like a small wire cage, the stint retriever is passed through blood vessels in the groin towards the brain to pull out a clot. I would say this is up there with the greatest inventions that weve brought to the medical space. Reporter in a new study out today, researchers found how effective it can be, but time is critical. If a stroke victim gets the stint retriever and medication within two and a half hours of their first symptoms, 91 will have little or no disability. After 5. 5 hours, it goes down to 41 . For now, the procedure is offered in just a few hundred hospitals across the country. Including 96 accredited as comprehensive Stroke Centers by the american heart association. What do patients do who are not close to those Treatment Centers . The most important thing the patients can do right now is to get to their nearest hospital. Reporter the warning signs for a stroke spell fast, face drooping, arm weakness, speech difficulty, its time to call 911. For rush, hes back to doing what he loves. I would surf every day if i could. Three times a week would be awesome, ideal. Reporter making waves across the country, a revolutionary treatment, dramatically improving the odds for stroke patients. Rehema ellis, nbc news, new york. Were back in a moment with fizzling soda sales, and what is set to overtake it as americas drink of choice. More americans are putting down those cans of soda for a healthier option these days, as soda sales lose fizz, bottled water consumption is said to overtake soft drinks this year for the first time in the u. S. Americans are expected to drink nearly 27 gallons of bottled water in 2016 compared to nearly 26 gallons of soft drinks. A murder mystery in texas. A mother of three found dead inside a church where she was preparing for an earlymorning fitness class. Now police are searching for her killer, a suspect caught on chilling video dressed in what appears to be Police Tactical gear inside that church in the dark of night. Nbcs Kerry Sanders has the details. Reporter the Surveillance Video shows a person dressed in Police Tactical gear, face and head covered. Authorities are unsure if its a man or a woman. But investigators say thats no officer. Rather, its the suspected murderer. Killed 45yearold missy beavers, her husband of almost 18 years, outside his home today. My wife, she was a great woman, a great wife, a great mother, a great friend. Reporter the 45yearold mother of three had come to the Creekside Church of christ at about 4 00 a. M. Monday to teach a fitness class. Camp gladiator. Usually the class is outdoors. But because of rain, it had been moved indoors. We dont have any idea, or any evidence that things were actually taken from the facility. But a lot of damage in the facility. Reporter detectives say the person in the video was already inside the church when beavers arrived. This person is 6 foot tall. If you look at the mannerisms of the person, how they walk, theres something very distinctive there that somebody has to be able to point this out. Reporter tonight a woman who prided herself in fitness, who was in shape, and unusually strong, is dead. The best lead police have right now, that video of someone posing as a cop. Kerry sanders, nbc news, miami. When we come back, the actress who everybody loved. Looking back at the life and career of one of tvs favorite moms. Peggy vo how iphone users are inadvertantly handing their personal information to identity thieves. Raj vo and the south bay olympian coming clean about the unusual way she got her start in table tennis. Next close next. Finally tonight, we remember one of the most beloved tv moms of alltime, Doris Roberts who played ray romanos prying mom on Everybody Loves raymond and other memorable roles over her decadeslong career has passed away at the age of 90. Tributes are pouring in from costars and fans. Nbcs joe fryer has a look back. I can contribute. Im not just some trophy wife. What contest in hell did i win . Reporter few actresses have captured the essence of an overbearing mother and meddling motherinlaw quite like Doris Roberts. Well, debra, i was coming over, and then i noticed that your children were starving. Reporter shes best remembered for playing marie barone. Yet her career which spanned seven decades featured dozens of movie roles, not to mention more than 100 tv programs. She was even on the love boat. Perhaps roberts biggest break came in the 80s when she scored a part on Remington Steele originally written for a younger woman. Age was a constant punch line throughout her career. Whether accepting one of her five emmys this is what happens when youre young and sexy. Reporter or selling doritos. Im a youthful 32. Reporter but ageism was a huge issue for her. You dont see a picture of any woman in any magazine over 40, unless youre selling depends or viagra. Reporter roberts lived to age 90, and is being remembered by people like ray romano. Doris had an energy and spirit that amazed me. Everybody may have loved raymond, but we all adored doris. Joe fryer, nbc news, los angeles. Thats going to do it for us on a tuesday night. Im lester holt. Before we go, take a look outside at rockefeller plaza. Were starting this evening, where were airing on the big screen above the today show studios, if youre in new york, on west 49th street, stop on by and take a look. On that note, for all of us on nbc news, we thank you for watching. Have a good night, everyone. Nbc bay area news starts now. Were hoping to spearhead this movement and say these are faces to people that youre displacing. Right now at 6 00, it is a problem some say hasnt been dressed in decades. People are crowded into San Jose CityCouncil Chambers right now hoping the city will take the first move in solving the problem. Thank you for joining us tonight. Im peggy bunker. Im raj mathai. Hundreds of concerned people are demanding more protection for renters. Theyre calling for stricter rent control and assistance for the people being forced out by rising rents. Robert honda is at city hall in san jose. Things have changed in san jose. Many rental laws havent. What could happen tonight . Well, theres going to be a lot of emotion here, a lot theres already been a lot of shouting inside the meeting, a lot of anger brewing, and the council has not addressed many much these issues for years. Tenants say the time is now. Danielle is working on the san jose zombie 5k run, a popular event to raise money for parks in san jose. She is known as a hard worker and she has to be to stay atop her rising rent. As a renter, im barely making it by myself with having six parttime jobs, a single mom. And paying the high rent that i have here. Reporter the San Jose CityCouncil Chambers are if i would and so are the overflow rooms as the city takes on rent control and other