End of the interview. How they say this movies message hits close to home. And once the chiseled gladiator. Now Russell Crowe is a victim of body shaming on social media. What hes saying about his fuller physique. But first here are the nightline 5. And number 1 is coming up in just 60 good evening. And tonight we are on an adventure to the heart of the peruvian amazon. There you will find a frog whose poison is said to possess healing qualities. But the key word in that sentence is poison. So why are so many people going all this way to take all this risk . Heres abcs Mariana Van Zeller with the latest installment of our series into the wild. Reporter in this otherworldly darkness of the amazon the only thing one can be sure of is that youre being watched. All the sort of most dangerous creatures, the poisonous snakes, they all like to come out at night. Look, a fish just jumped into the boat. Weve put ourselves at the mercy of the untamed wilderness. Whoo. In search of a fabled amazonian tree frog that has long been used by tribes here. Well see how long it takes to find this frog. Now in high demand thousands of miles away in the hills of los angeles, where ceremonies like this one have become the latest cleanse trend. Here these people are poisoning themselves with the toxins from that frog. So just remember the breath is your guide. Reporter called kambo or sapo its applied to burned skin and absorbed into the bloodstream. Kambo is something very unknown. Reporter this process is not for the faint of heart. You have to have a sense of courage to come here. Reporter as you can hear. Throwing up. The effects of kambo. Reporter practitioners say its worth it. I felt like superwoman. Reporter claiming the process can help cure depression, drug dependency, heart problems, high Blood Pressure and gastrointestinal issues. I believe everyone should go through this experience at least once in their life. You are basically putting the poison from a frog into your body and your system. Did that scare you at all . It did kind of scare me. But i kind of trusted something, my intuition. Reporter right now theres no research indicating benefits to human health, and its not officially classified as a medicine. There is no regulation of this treatment by the fda or other authorities. Do you think there are any dangers associated with kambo . Like any medicine, if you take it and do it with no knowledge there is obviously more danger. Kambo requires a certain amount of preparation. I would say its not wise to do kambo if you have not done it before alone. Reporter kambo is legal in the u. S. , and the people here seem to think its working. So we decided to travel to where this ancient process began. To the amazon rainforest to see if we could actually find the creature at the center of this craze. It was a very early morning. We woke up at 5 00 a. M. , took a twohour bus ride, and then another 2 1 2hour boat ride, and now were here in the middle of the amazon, taking this motorized canoe another two hours up river to the campsite. Gracias. This is the dry season. So we have to take the long way around the river to get to the campsite. But now hes saying that 90 of the tourists that he brings out here are coming to look for the amazons medicine, and hes saying recently theyre looking for the frog. So were going into one of these little shortcuts, these little tributaries. There are thousands of these little tributaries all around the amazon. Having been to the amazon a few times before, im always struck by its beauty and its challenges. Gracias. Reporter its the dry season here. The rivers really, really low. So in this case we had to get out of the boat so they could pass. After getting stuck a few more times, our twohour journey gracias. Reporter turns into three. But finally and were here. Which is where were spending the night. Reporter joining us on this adventure is peter arnold from switzerland. So you did the kambo, the sapo . I did it, yeah. What was it like . You throw up. You feel very sick. You feel like youre going to die. And finally its going away, and after that you have the kind of feeling of being relief. Why did you decide to do it . It was a unique experience. I just wanted to know what it feels like, you know. Reporter my team is getting curious about this experience too. But to do that we have to find a frog. The sapo comes out at night and usually only when its really dark and cloudy nights. Reporter as twilight settles its time to start the hunt. We have our snake boots, our headlights, our mosquito repellant. Okay. And the rule of the jungle is that especially at night you dont touch anything. A really shallow spot so we have to get out of the boat. Be careful where you put your feet. Oh, look. Not our frog but it is a frog. Its been almost three hours. We havent been very lucky so far. So theyve decided to park our boat and head on foot into the jungle. I hope they know their way back to the boat. Oh, wow. Look. There it is. That is amazing. Big, huh . Grande. Reporter here we hit the jackpot. We find not one but two frogs. At night they just sit there, dont do much. During the day theyre camouflaged so, its almost impossible to find them. Reporter on our way back we almost lose someone on our team in the process. Reporter jasmine, our producer, just lost her boot in the swamp here. With luck we easily find our way back to the boat. Three hours, we found two frogs. Heading back to camp. And tomorrows the big day. Reporter this camp is owned by amazon explorer peter gorman, the man owho claims credit for bringing sapo to the united states. Somehow just seemed to explode on the scene. Its the emerging stages of a small but legitimate phenomenon. Reporter as treatments from the amazon like kambo become more popular, gorman says one cant ignore the impact it could have. I dont think any Indigenous Group in the amazon is large enough to be able to handle busloads of tourists coming in. I think that would destroy their entire way of life. Reporter the next morning its almost time for to us try for ourselves. But first the toxins must be extracted. They just have these four sticks. They open up the legs with these strings and then it starts secreting its poison. Translator all the secretion you see is protection. After this the frog will be a little weak. We free it, and it will eat to recuperate its energy. I get a little quality time with the frog before hes released back to the wild. Its cold and sticky and wet. And they say you can hold it, its not harmful at all unless you hold it and then you put it in your eyes or your mouth. [ speaking spanish ] okay, little buddy. Reporter while the frog regains its strength its peters turn. The frog poison has been dried onto a stick and in the traditional amazonian way reconstituted with spit. What are you feeling . Its like heart pounding. Thats a start. So i sit down . Reporter after making it all the way here, i cant back down now. In 15 seconds he says im going to be able to feel it. Blood is rushing to my eyes. My head. Your heart is racing as fast as if it was as if youd just run a marathon. How are you feeling, peter . I think i might need to throw up. The question is why do people do this to themselves . Im going to find out after, how i feel. I believe it really works. The detox. Reporter a few hours later peter is feeling better. And as for me . Still a little lightheaded but also full of energy. Almost back to normal. Reporter miracle medicine . Maybe not. But the magic and wonder of the amazon, undeniable. For nightline im Mariana Van Zeller in peru. Next, alec baldwin and lisa kudrow shared a fling on friends. Now theyre reunited in the new animated movie the boss baby. And later, gladiator Russell Crowe has the perfect response to people trying to bodyshame him on social media. Per roll more doing chores for dad per roll more earning something you love per roll bounty is more absorbent, so the roll can last 50 longer than the leading ordinary brand. So you get more life per roll. Bounty, the quicker picker upper at red lobsters lobsterfestime. Any of these 9 lobster dishes could be yours. So dont resist delicious new lobster mix and match or lobsterfest surf and turf because you wont have this chance for long. When youre close to the people you love, does psoriasis ever get in the way of a touching moment . If you have moderate to severe psoriasis, you can embrace the chance of completely clear skin with taltz. Taltz is proven to give you a chance at completely clear skin. 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The last time alec baldwin and lisa kudrow shared a screen together, he played her annoying boyfriend on the hit sitcom friends. Now theyre back together and hes playing an even more demanding and emotionally draining man in her life. Her baby. Heres abcs nick watt. Meet your new baby [ slow motion brother ]. Reporter whoever thought to put the voice of alec baldwin with a baby with a briefcase is a genius. Goo goo ga ga. You cant not have fun playing a baby in a suit with one of those diaper things. I guess your wifes doing all the diaper changing in your house. You dont even know the name of it. Fine. I can talk. Now lets see if you can listen. Reporter jimmy kimmel plays his dad. Lisa kudrow plays his mum in the movie. Is that really that strange, though, when you think about it . I would be the baby from the two of them i think. Reporter perhaps baldwins most highprofile dig of late the president of course on snl. Siri. How do i kill isis . Reporter to acclaim from many but not the president. Not funny. Cast is terrible. Always a complete hit job, hes tweeted. Baldwin says he may not play the role much longer on snl. Unclear how much longer. But he is now clearing up with cofounder of spy, radio host, to write a book charting trumps first 100 days. Kurt anderson and i are writing a book called you cant spell america without me. Thank you, by the way. Thank you. A lot of pictures. Kurts going to do most of the writing because kurts a great writer. What is your role . Are you im trump. The two of you are writing it together . Coffee table book pictures. Oh, its for fun. Its not a historical document, in other words. I mean, its not like youre not i didnt understand. Have you seen him on snl being President Trump . I dont know what youre talking about. She knows. Shes playing phoebe right there. Baldwin and kudrow actually last worked together on friends circa 2002. I was her like really annoying boyfriend. We probably should get going. Ha, ha, ha, ha classic ross. Fire her. And dont make me ever talk to a woman that old again. Reporter and of course he was jack donaghy in the longrunning highly acclaimed 30 rock. Jonathan, youre fired. Why is your tie a little bit squint . I did 6 1 2 years of a tv show and thats all you have to say, is i messed up my tie . You turn to her and go your show is a great show. And your tie is a mess. Im just surprised nobody ever can we start again . Im surprised nobody ever told you that. For multiple reasons we need to start again. He was so good in glengarry glen ross, perhaps hes never managed to escape it. Coffees for closers only. Ripped off on posters for the boss baby. By the way, he dressed his son as the boss baby for the premiere. You do get constant these kind of corporate monsters when in real life you seem like quite a nice chap. I think i am. Ive never played a movie part that was really what i am. Whats going on inside of me. Almost got to fix that. Its not about age. Its about intellectual heft. Right. Where did you go to college . Vassar. She went to vassar. Where did you go . I went to paconic community college. Mmhmm. That was so polite of you. There is no such thing as paconic. Where did you go to college . St. Andrews. They have a college at the golf course . What did you study . Modern history. Which is dont look at me that way. Hes like, modern history. Ill have you know. Baldwin claims donaghy and boss baby share a soft core. Inside those lines you see hes covering something. Hes very needy. He does that to protect himself. Hes completely full of you know what. Who are you . Lets just say im the boss. All right. Back to boss baby. He has a mission to get a cloned puppy that babycorp. Fears will steal all the love in the world. Behold our mortal enemy. Kids feel theres a finite amount of love. I was always asking my parents who do you love more . What did they say . We love you all equally. Baldwin lives in new york city with wife hillaria and three young kids. The message of the boss baby is sibling peace is a good one. I have a 3yearold, 1 1 2yearold and a 5monthold. In the end we have to hug each other and kiss each other and say they love each other. My wife is very smart that way. What kind of a dad are you . Do you let it work out between them or do you intervene . I try to let them slug it out. You do. How scottish of you. My god. To a point. Reporter baldwin himself, dont forget, brother of billy and stephen. When i was a kid, my parents had six kids. Boof. Everybody breaking windows and shooting arrows into the wall. But did you send each other to the hospital ever . A couple times, yeah. So hes familiar with the territory. This to me is about older brother who basically hates the new arrival. But you know, love conquers all, dont you think . Yeah. I was choked up by the end of the movie. I was. I was. I believe you. Reporter sure. I mean, i was laughing. 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Remember, thats charmin in there. No wasteful wadding we all go. Why not enjoy the go with charmin. For me, it was heartwrenching. Bea it takes a toll on everyone. I mean, its a depressing disease to watch unfold before your eyes. You just dont see the persons soul is, like, gone. Lisa this disease just ravages a family. It changes your life. The magnitude of it is indescribable. Art now is the moment. If we work together, we can stop this epidemic. Grace contact brightfocus and learn more. And finally tonight, back in the day when i first saw that movie gladiator, i never imagined it would come to this. My name is maximus decim decimus meridius. He stunned with his chiseled form in gladiator. But now recent photos show Russell Crowe is sporting a different look. Tabloids taking note today and page 6 tweeting a moment of silence for Russell Crowes hot bod. And a tweet saying howard stern just goofed on your weight. Crowe was quick to reply, tweeting back i can bench press young howard. He cannot say the same. March. Jack ely. Dont get upset. Im not here to hurt you. Reporter just last year the alister spoke out about gaining weight for the movie the nice guys, saying i wanted it to be the physical juxtaposition of ryan gosling. So with talk of a possible gladiator sequel what would our gladiator look like . Director ridley scott weighing in saying russells changed a little bit. Besides the need to resurrect maximus we still think crowe has that studly gladiator in him. Thank you for watching abc news tonight. As always, were online 24 7 at abcnews. Com and on our Nightline Facebook page. Thanks again for watching. And good night