Gimmie that your automobile turn off that smokestack and that damn radio hum along with me hum along with the tv no ones gonna stop [ applause ] tonight on nightline. It could improve your sex life and battle cancer. The ultimate cure in these venomous creatures . Too good to be true . Were scouring for scorpions in search of an unlikely wonder drug. I have absolutely no doubt that it saved my life. Superheroes in the making. Thor, iron man, the avenger. The brandnew agents of s. H. I. E. L. D. Behind the scenes on the magic of marvel. And the winner is going berserk, eminem is having a major moment at the youtube awards, along with soon to be sta stars. Well tell you whos making the cut in the best videos of the year. Good evening. We begin with breaking news. At approximately 9 30 eastern time right before closing at one of the largest shopping malls in the united states, just outside new york city, at least one shot was fired bringing hundreds of area Law Enforcement officers to the scene. Abcs geo benitez is there with the latest. Reporter good evening to you. No injuries reported so far. Thats the headline and the good news. But officers are still trying to figure out what happened here. Witnesses say they saw a shooter wearing an all black biker helmet and they heard a gunshot. Police were able to find one single shell casing inside this mall somewhere near the nordstrom store but again we dont know exactly what happened here, why that gunman would have done this. So lots to figure out here. Thank you for that. Abc will stay on the story overnight and have the latest on good morning america. We turn now to a poison that some say packs a powerful medicinal punch. Scorpion venom. Some people claim it fights everything from impotence to cancer. Lush forests of the Dominican Republic are crawling with these creatures. And thats where abcs matt gutman reports from tonight. Reporter turn on the black light and see if they are here. Look at this. Oh my god. Reporter to most of us, these scorpions, best hunted in the jungle of darkness, is the stuff of nightmares. But now they are also being touted as the stuff of salvation. Everything from battling auto immune diseases and enhancing your love life. And the most extraordinary claim of all, a new weapon in the fight against cancer. And the sole active ingredient is skittering at our feet. The venom packed in the scorpions stinger. I have seen people getting well immediately. Reporter russian emigre doctor and his company have made the controversial claim that the chemical in the venom that causes paralysis in prey targets and killed cancer cells. And they have managed to harness that into a drug. Are you convinced . That this fights cancer . More than convinced. Reporter a drug not approved by the fda, but available for sale in the u. S. For 700 a bottle. A substance that thousands of desperate people, many of them americans, are literally betting their lives on. There you go. Peggy, a grandmother from texas, is one of those people. I have absolutely no doubt that it saved my life. Reporter in 2011, she was diagnosed with stage iv breast cancer. She says doctors told her and her husband larry she had just two months to live. I arranged for what i wanted for a funeral. Reporter as a lastditch effort, peggy started taking escozene. Within six months it was gone. There was absolutely no more cancer left. Reporter did scorpion venom really conquer her cancer . Or is this just the latest miracle remedy separating desperate people from their money . Better do it before that storm gets here reporter we decided to find out more about this supposed wonder drug for ourselves. Wow. Reporter but getting close to the source, that venom, is no simple feat. This is spectacular. Reporter because it doesnt come from just any venom but the venom of blue scorpions found only in cuba and here in the remote mountains of the Dominican Republic. Pretty amazing. Reporter from above, the lush forests carpet these peaks. On the ground, a more prickly reality. As we hiked to the reservation we were greeted by young villagers. He just came up to me with i guess a salt shaker. Inside . Three scorpions. Dont try this at home. Reporter and the boys, so used to handle these creatures, offer me a handson tutorial on scorpionwrangling. And then on to what must surely be the only scorpion reservation in the world. Scorpion mecca, complete with 83,000 wriggling residents. You want to do it . No, you do it. Theres one. Reporter turn over a stone or peer into a bamboo segment, and there they are. They are quite amazing and mysterio mysterious. Reporter more than mysterious. He and his barn swear escozene is downright miraculous. Kills 95 to 98 . Kills 95 to 98 of cancer cells . Yes. Pretty big claim. We know. Reporter in addition to attacking cancer cells, they say scorpion venom might battle auto immune diseases. Everything from hiv to hepatitis. The Company Claims it can even help with er male potency. Big farmers spend big dollars on research and development. How come they havent found the magic scorpion cure and you have . Usually Big Pharma Companies dont work with natural components. You cant patent natural product. Reporter escozene isnt the first Natural Remedy purported to cure diseases. While some have turned out to have significant medicinal value, most have been resoundingly debunked by science. Think shark fin, rhino horn, and the proverbial snake oil. When you tell people that this medicine is going to help them possibly cure cancer, they have no reservation doing it . Youre giving them false help. We never use cure cancer. Thats the subsection. Helps your body use its natural ability to cure cancer. People will only see cure cancer. Fight cancer. Eating vegetables can help you fight cancer. You dont want to use the word cure but thats what the subtext is in this drug. The subtext, obviously we want to help to the maximum ability that this medicine can possibly help. Reporter they say its been helping people here in the Dominican Republic for generations. She says she always has a scorpion. Like the shopkeeper maria who keeps scorpions bottled in turpentine with her at all times. Using the venominfused solution helps heal her arthritis, she says. And will even help my runners knee. It didnt. But it did keep the mosquitos away. Next up, this modest rented lab in the capital santo domingo, they extract the venom. Why dont you have a go now. Are you serious . Okay. Reporter thats right, they wanted me to milk a scorpion. Were going to be friends. Im just going to milk you. I dont want to squish him. This is not as easy as it looks. Reporter they say the scorpions are unhurt as five to seven drops of the venom are extracted from them every month. Only a tiny amount is inserted into these bottles, each of which goes for about 700. The bottles are sold on the internet and shipped to patients like peggy howe. I love you, mom. Its absolutely given me my life back. I got to see my granddaughter born. I wouldnt be here at all if it werent for escozene. Reporter she was so convinced it saved her life, she had a scorpion tattooed on her ankle. Theres my escozene. Do i believe in it . Reporter but none of the medical files peggy provided seem to show that it healed her. There is no Scientific Evidence to show that this drug works in treating patients with cancer. Reporter dr. Len licktenfield is a deputy medical director of the American Cancer Society and has seen too many claims like this that have turned out not to work. Cancer patients have enough to deal with to have to deal with unverified and undocumented hope is is a burden that no one should have to bare. Reporter the doctors skepticism wasnt the only thing that gave us pause. Right there on its website it says escozine is approved and certified for oncological treatments. Click on the link and you learn they received this approval only in the Dominican Republic. Are you approved in any other countries to make these claims . Were also registered in russia, belarus, kazakhstan, vietnam. Reporter when we alerted its website may violate fda regulations against marketing drugs on the web without fda approval, the company conceded it was rapidly making changes to the site. But there was another much more important issue. Medolife could not produce a single peerreviewed study showing it works. Even the 8,300person Clinical Trial they presented to us. Turns out the results of that trial are not acceptable by american standards of science. Its one reason the doctors say they warn patients to be wary of unproven remedies. Unfortunately, many more times than not, the original claims that were made for some of these drugs dont work out. Just an amazing factory. This little gland here. Reporter the doctor acknowledges the drug needs significantly more testing before medolife can even apply for fda approval. Shake it up. Reporter but howe says she doesnt have the time to wait. Her cancer is now back. After a hiatus from the drug, shes putting her faith in the venom of scorpions once again. Hoping it will save her life. For nightline, im matt gutman in the Dominican Republic. Our thanks to matt gutman for that. Next, were infiltrating a Government Agency but probably not the one youre thinking of. Once wrote something on a sheet of paper and placed it in his factory for all to see. Four simple words where the meaning has never been lost. The challenge always accepted. And the calling forever answered. 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Superhero fans no longer have to wait for blockbusters at the cineplex to deliver the magic of their favorite characters. Now they are hitting the screens in a living room near you. Yes, the agents of s. H. I. E. L. D. Have their own tv show, and were getting in on the action behind the scenes. Reporter marvel are the masters of the superhero spectacular. The second installment of thor hit theaters this weekend. Anyone else . Reporter with a stable of the galaxys mightiest and isnt that correctiest superheroes. Does mother know you weareth her drapes . Reporter the 50year history of comic book gold. Marvel is now moving into a new frontier. Television. A brand new show. Agents of s. H. I. E. L. D. Nightline was granted an exclusive peek. We should buckle up for this interview. Reporter unprecedented access to witness the magic made. So secretive, were not even allowed to disclose our location. Superhero fans no longer need wait for the two or three movies released every year. I want to show you our fabulous command center. Reporter now they can get their fix every tuesday night. When a posse of international uberagents straight out of the comic books, marvel has built this entire show around just one wellknown character. Is that one of starks . I dont know. Guy never tells me anything. Reporter with a coat, a tie, and a sensible haircut. Even i dont know what it does. You want to find out . Reporter agent colson, who was killed off in the avengers movie or so we thought. Did you feel a lot of pressure bringing this to the small screen and youre the main guy . I probably should have. If i thought about it much i should have been really terrified. Reporter cranking out a mini movie every eight days. Going around the world on their extravagant bus there, command center, bunkhouse, forensics lab, and exotic car. Dont touch lola. Please dont. Its okay, you can. No, you can. Reporter theyre trying to appeal to comic book people. Im one of them. I want them to enjoy this. I want me to enjoy it. Reporter and appealing to those like me, who have never read a marvel comic or lost themselves in a superhero movie. They made me watch but i enjoyed that. Are you saying that because youre standing in front of my face . No, i liked it. Reporter thats Chloe Bennett who plays sky. Are you going to show us something now . Youre the hacker, the outsider whos blot in to fit the mold. You only can describe her by doing these. Yeah, yeah. Ten minutes. Reporter why did people like this . Dont know the exact answer. Its the world of superheroes seen through the eyes of real people. Does that make sense . Reporter and theres internet clamor for sparks between sky and this guy, the luscious, the lacinic agent ward. Played by brett dalton. Things are moving too quickly. Im a proper girl, you make me untidy. Hes amazingly attractive, have you seen his cheekbones . Reporter in the world of marvel, fan pressure just might work. Thats partly what brought agent colson back from death. When he was dead people started posting all over the globe. Colson lives. They wouldnt accept it. Suddenly hes back and hes got his own show. Reporter they promise to reveal very soon just what went down to bring our everyman superhero back to life. I feel that youre a beacon to all men in their 40s. Who want to be fabulous. I feel yes. I feel that, you know, you seem like a potential s. H. I. E. L. D. Agent, if one who isnt secretly already. What do you think . Reporter colson makes me feel like i could really be an agent. Im weapons trained. Are you . Oh yeah. You can field strip it . No. You want to be able to have mom, dad, junior, sis, all be able to sit and go, thats my favorite character. And you made the geeks british. So you can laugh at british people. Actually, theyre the smartest ones. Reporter ian comes from the same part of scotland as me. Hes my people. When it comes to beautiful women, i cant keep agent of s. H. I. E. L. D. Kind of cool. You get to wear the coolest outfit. I do. And its the most comfortable. Reporter on the show, shes a badass fox dressed in leather. You play this very scary not scary. Just misunderstood. Really . I think so. Reporter tomorrow nights episode, episode six, is a doozie. Even if youre the most manly man, the most alpha male and you dont get a little moist around your eyes, you ought to have yourself checked. Any idea what can cause this . Can you just go over it again . Did not. She did not. You think that was going to work . She didnt tell you a single thing. Nick watt on nightline. Level seven. Our own special agent. Agents of s. H. I. E. L. D. Airs tuesdays on abc with a new episode coming tomorrow night. Marvel is owned by our parent company, disney. Next its awards season at youtube and the best video of the year are waking us up. It really made the difference between a morning around the house and getting a little exercise. 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Make the holidays pop. He loves me. He loves me not. He loves me. He loves me not. He loves me thats right. [ mom ] warm and flaky in 15, everyone loves pillsbury grands [ girl ] make dinner pop on tonights feed frenzy, video vanguard. The first annual youtube music awards took place over the weekend. The artist of the year, eminem seep here during the show in a live music video for his song rock god. Some winners might be harder to identify like the south korean girls generation and their very colorful music video of the year. I got a boy. Nominees were partially based on youtube views, likes, shares, and comments. Which weve