How could things have gotten this bad a year ago a tool box fell on all things down himes foot it was just a small wound and down time thought it wasnt anything to worry about but he didnt know that it dangerous multi resistant pathogen was in the wound. Now anyone who wants to visit him has to follow strict safety procedures. At all cost the pathogen must not be transmitted to another person. Through as ive been you know would go up to him so quick to begin with i was too scared to look at it. But then they said to see what it looks like. The time my own foot it looked like a pizza margarita. Yet a lot of the green red blue or love. His food had to be amputated. The doctors in thailand where he lived could not come to grips with the new super pathogen. Whatever because until its all gone and agent warning has come from the World Health Organization socalled multi resistant pathogens are on the increase worldwide. Their Research Standard out our vioxx. Was. We are loosing the power of the office more and more. I think we could say we are on the threshold of a post antibiotic era. Fatalities will dramatically increase there will drive some total nurses. To man to the arctic should not enter the environment do often they must not enter the environment they just make things worse. Asla know luke is fighting for his life. He has been in intensive care in Berlin Charity hospital for six weeks. His sons visit him every day. Highly resistant pathogens caused blood poisoning and try to give him hope. For so many seasons he knows they were there for him. Professor day is treating the patient a little im glad to see you. The professor doesnt know how the pathogens entered his body. It is not what i would like to have another brief chat with him. As your sons are here. I havent any pain right now. But can you understand this effort fifty yes extremely well i think you all know as relatives that this is a highly resistant pathogen that cannot be cured with antibiotics. Even the one that is used in extreme cases it is also. The know you are doing all you can. For others it is very stressful for the patient and his family that we cannot treat him with antibiotics. And unfortunately we can do nothing to relieve that concern. The doctors have tried all conventional antibiotics in vain but now there is one last hope. We can only be session when the patient is id say mobilised is awake breathing on his own and there is no increased risk of a new infection with. Every new in fact. Would be extremely dangerous with this patient before and that can quickly become life threatening as it was for right now i cannot say for hes going to make it one time he asked him oh man come on only son and says he will back us. But where did these new pathogens these highly dangerous journals come from a cluster of flu bad is a doctor at like Six University hospital he carries out research on the topic ten years ago these pathogens were hardly known in germany now thousands of patients are affected. If you can only move an organ transplant all kinds of organs and stem cells we can cure leukemia and so on those are huge advances. But we can do all of that and still lose a patient due to a stupid infection from some stupid germ that someone has brought back from an overseas visit for example its. One we carried out a study or we found that over seventy percent of tourists who visited the science in india came back with a multi resistant intestinal bacteria and the stent don back to you because you did so recall. From. India is home to an especially large number of bacteria which are resistant to antibiotics and at the same time indias pharmaceutical Companies Supply the entire world with antibiotics researchers claim there is a correlation. We traveled to hyderabad indias pharmaceutical capital. Dr li that the companys us. In india alone each year some sixty thousand newborns died due to resistant pathogens. Theyre increasingly spread through food the environment. Goods but also tourists and are now more frequently reaching europe. The World Health Organization warns that these special strains of bacteria are resistant to most types of antibiotics. This notion studies and Research Show that a number of incidents of contamination with multi resistant pathogens in people in the environment and in the food chain in india are much higher than in other countries. And that if we look at that globally you want to find the key to controlling this antibiotics crisis memory must look towards india cause. We want to track down these new kinds of bacteria environmentalist and well diag carr is willing to help us together with diana carr and dr leave out we want to take samples and have them tested in germany to find out which antibiotics are of no use in fighting these bacteria when it dissolves when we leave that explains the process of gathering samples is the one to take the sample and they decide to start by testing the water at the top theres least a skiffy. Just market way of take a listen. Here. So we take it from here i think that we take our first water sample at a roadside food stall. The samples must reach the lab within thirty six hours. Of the us. Shoot Industrial Site is nearby. Could this be the source of the dangerous germs. Drugs are produced in hyderabad for manufacturers from all over the world. Many of the antibiotics used in germany originate here. This sad hopes to attract clients. Cluster has come to be recognized as the drugs capital of india it alone accounts for one third of indias total drug production. With nearly two hundred bug drug and intermediate manufacture units genius i boss with the motto many moments spectrum maximum facilitation. And this is what minimum inspection leads to allegedly treated waste water from the factories ends up in the river. The stench of decay excrement and chemicals is horrific. The quick fix. To fool. And theyll tell ya car tells us that farmers use this water to irrigate their crops it used to be drinking water. Actually this form is because of the combination of finest reference and the most serious. This one advance this arming area is also getting one of their. Very very. Large. Because theres a lot of demand for the bugs and. Medicines so are the demand is growing and in pharmaceutical industry. With. Increasing now releasing on nestle or in france so rich are coming directly but this is. For the pharmaceutical giants its a question of money treating waste water properly is complicated and costly. Diag our shows us a sewage pipe in an industrial region. Just want to this is the source of the call this what we have to. Dump like this lake instead. Of. The filthy water collects in an open pool if we find antibiotic residue in this water it would be a breeding ground for super pathogens. Bacteria are extremely adaptable they can develop Defense Mechanisms in order to survive. Only super pathogens survive when they come into contact with antibiotics. They can pass on their resistance to antibiotics to other bacterial. And the number of pathogens keeps growing. One single pathogen can turn into over a billion in just a few hours. Via the environment there transmitted to human beings and animals and spread even further. Ok well fortified ive. Been smelling awful. A little uncertain. What an insane brew discussed and. If we find antibiotics here then well probably find what. Appeared resistant bacteria that are able to survive. We have to take two samples one is tested for antibiotics the other for resistant bacteria if we find exceptionally high levels of antibiotics it will be an indication that the pharmaceutical companies are contributing to the emergence of super patho gents. The resistant bacteria reach the skin or intestines by a food or water but the germs are also transmitted further. If someone gets ill or is injured they can pass on serious infections given antibiotics dont work the bacteria quickly spread and can lead to life threatening blood poisoning. The if i the continental is one of hyderabad best hospitals dr gold paul is worried by the fact that a growing number of patients are being admitted with highly dangerous pathogens but he sees a correlation with the nearby Industrial Site. Or that. Industry answer to that and that together with a not isolated Industry Society hospital theyre all interacting with each other right in this and were out of control room how soon or maybe in five years time we start having epidemics of these back today no hospitals and lead when the source ip. Suits father has been at his bedside for days soo crude is thirty one years old he was always completely healthy until suddenly he was infected with a multi resistant pathogen. No antibiotic has helped cure his infection. Suit has been in an artificial coma for five days now. In utter minutes and in about and its very sad. My son makes our family happy but i fathered him so much and he grew up into a fine young man if something happens to him i couldnt bear it or to hear another day i just wanted to get well again carneval another global. The life support system sounds an alarm never go to the doctors fight to keep the patient alive. Today only god that if the official regulatory even. If you live it up all of the. Good out of just one of. My friends from europe for you. To feel good it really be true that the manufacture of lifesaving drugs contributes to the existence of super pathogens. On the woman but the modern problem of the whole claims of the missing editors here. In the m. S. N. Is an important partner for many german pharmaceutical companies. In its commercial it presents itself as being environmentally friendly. Green at m. S. N. The bar drinks have a dream. A dream of spreading wellness across the globe. On manufacturing units assyria discharge facilities and comply with the highest Health Safety and environmental mess. With an ever growing market reach and a white partner base. We have been synthesized a success money on a decade and continue to do so every day i miss and exports worldwide and makes drugs for leading pharmaceutical companies he is proud to say exports to germany and has certificates from International Inspectors from the e. U. And even hamburgs health authority. Inspectors from hamburg visit hyderabad almost every year as well as colleagues from other german states and other even nations. They make sure the drugs conform with european norms. When i look at the box with my tablets inside i couldnt imagine under what conditions there may turn. Out is it all these companies here are allowed to export to europe it. Is a subject if you want with us the certification process describes how the drugs are manufactured in the pharmaceutical process. But what happens outside the factory where the waste water goes and i would processed or whether there are at about x. And the waste water is not mentioned in the certificate and thats if its you will often hide. The inspectors cannot control Environmental Issues there is no legal basis for that. But we were able to collect samples outside the factories. To hide Small Holdings from. A lot of people live near the factories. And theres a lake nearby. If it is contaminated the fish will be as well. Or. So the selfishness over yes i. Think its the fish. Die your car hopes are samples will confirm his suspicions. And which plants rouffignac. But theyre going. Through the right line fist and then give a little better to directly. And insist im horrified like life cut us till five years ago thats what you can see just how disastrous the situation here really is and it becomes clear how hard it will be to change things and that really is to be honest that discourages me of course he needed to hide never thought that they would just dump the waste into the lake meant look people live here im often because i never thought this could be possible. To say go your department the seriousness of this god. This is where secrets family lives hes the young man we saw in the hospital with his father. None of the antibiotics helped the infection spread through his entire body. So could died a few days after our visit. Someone turning points and then the doctor said all he could do was pray and stay at his side. There was nothing the doctors could do but you ended up and up until now we only have his daughter. Shes eighteen months out of their fourth. He was such a happy thought of court on should have had many more happy times without me. But now hes gone any. Secrets daughter crucially is the familys only comfort. Cicutto was buried a week ago. We take the final samples to test for antibiotics and bacteria from the musi river it flows right through hyderabad. In many places its just sewage. If we find a new super resistant pathogens here it would be a disaster they could continue to spread in the water and infect millions of people. Just this year plus year of the things that happen here will eventually be transported to germany via various channels and the pathogens will be carried by travelers or good some other mechanisms. As long as we dont solve the problems here well still import the pathogens to germany no matter how careful we are without our biologics caught is a problem of. Migratory birds can also carry the bacteria. We have thirty six hours to get the samples tested in german laboratories. That will test them for resistant bacteria. That will enable us to establish whether or not the pharmaceutical companies contribute to spreading multi persistent germs. Back in berlin deadwood us line no lose condition is improving the doctors are relieved the new antibiotic is working hes lucky it only came on the market a few weeks ago. Is awake and can manage to speak a few words he has lost fifteen kilos of muscle mass and is very weak a little. Of the movement that he gets to feel a bit better. He gets me are stronger you give me your hand. Are. You can you leftists. Can you keep it raised so difficult for you in any pain. Where does it hurt. You could your bones on my legs and your back. And your first i say if. It. Does move on well have to be patient its. The first your lungs must tell and then well take care of effect. He cannot breathe on his own yet but hopefully he is slowly on the mend. The. Doctor in the bed is back in germany the University Hospital lab examines the samples from india. Microbiologists want to see which antibiotics the bacteria are resistant to. You can see here they grew in large quantities. Sample number twelve is really interesting comes from the river mostly. That is to hyderabad like the elbow is to hamburger the spray to berlin it flows right through the city. The first results are available. And we are still in india so we agree to skype. And im curious to know what you found out. Is that theres greetings to india and ill try to be brief its far worse than we expected. But was there a time when you said it wasnt so bad or was it one piece of bad news after the other and if they made. The fence and i and all the samples show huge amounts of bacteria with huge amounts of resistant genes the worst kind imaginable if i had a patient with bacteria with such resistant genes i i would have difficulty treating it. Hadnt been tried and she really couldnt. Because the antibiotics dont work doesnt either and to an extent you hadnt expected. And the price if we found them in a paddy field stand in a wash basin in a cafe in the mens room in the city park in the city park itself in the surface water in a large hospital in either a battle and the worst case of all in the movie river in the movie river yeah you said the river was the most probable place because everything flows together but we took lots of samples right near the factory and thats. Up for us in the us in fact we didnt expect the waste water from the factories to be so badly contaminated that. This is look its a lot lot worse than we expected to see i mean. Thats the bad news of the fiftys out east. Here people want to spread good news india farmer week is one of the leading trade fairs for asian manufacturers. Indian companies are among the leading players when it comes to producing antibiotics their products are sold in german pharmacies prescribed by german doctors and used in german hospitals. And wesson is also here the company we waded through mud to get to. M. S. N. Is one of the leading manufacturers of antibiotics we found highly resistant pathogens in the samples taken near their factories. M. S. N. Denies any responsibility and questions our findings there were problems with waste water back in the ninetys but now the water is clean nobody here likes to talk about pollution. We meet the head of the association of exporters of pharmaceutical products. And id Like Companies to know that what could be much more than that required capacity that they can get up there in iran meant lets fix good a few say that their industry beginners frees us from other industries theyre mean theyre putting an equal importance to this for action see that there should not renew don went back to the public as antibiotics up against there and we find. Environmentalists pollution there has to be someone its months before it. Made me but. It is not like theyre going to it is it is when seen like that because they are not aware there is a members listed with their own director so Many Companies it is way into the common Treatment Plant. It is not being led old anywhere from the industry it was from the common Treatment Plant after treatment. The representatives stress over and over again that the factories do not cause pollution and caution us that any evidence we use should have a scientific basis. So we are out to prove it. A special lab is investigating the samples we took near the factories only if we can show that there are large amounts of antibiotic waste will we be able to prove that the factories helped to create super resistant pathogens. The process is complicated and lengthy. We have to be patient. You ask him larson is one of the worlds leading experts on multi resistant bacteria in the environment for decades now he has warned of the consequences of impure production of antibiotics in asia up until about ten years ago. People will look really aware of that there could be very high discharges of ticks to the environment. If there are more lax regulations and locks control over this charged environment this outsourcing might actually also promote more discharges to the environment but the major point is that there is such a high price pressure on our drugs so it really pushes production to do it in in the simplest cheapest way. Production in europe on the other hand is costly. This company is one of the last to make a basic component for antibiotics here Environmental Control is key waste Water Purification is expensive the company fears it will soon be unable to compete with foreign manufacturers. You know ripple chasten is also always the people to retain care to ensure none of us substances leave the factory and are able to enter the environment. Beach where the water in the mine river is a price if this price war continues we wont be able to stay afloat for much longer linger for a stick for it to feel. Ten weeks after filming production stops the price war lost to asian competitors once again. Alongside mobile phones and t. Shirts china produces medication. In Inner Mongolia manufacturers are building ever larger modern industrial facilities. And this factory is so huge it needs its own power plant. The facility makes the base substance for around one quarter of antibiotics worldwide. Chinese factories have also released contaminated waste water into the environment. State t. V. Made public two years ago and reported in surprising detail you would hope no fish caught in that mother was a stance of chemicals that makes us all drowsy. Im up and about what all of the new companies are suspected of disposing waste water illegally. Allegedly things improved after the report but we cannot verify that. Antibiotics are being produced in a smaller number of ever larger factories in asia that has dangerous consequences. When one chinese factory exploded in twenty sixteen a number of antibiotics soon became scarce in germany. And there are few manufacturers left in europe that could step in to bridge the gap. If we become dependent on wall nor a very few providers somewhere else in the world there is a problem with supply that can create challenges for us for life saving and to buildings the other thing is of course the Environmental Issues. Some ninety percent of the basic products for antibiotics worldwide come from china. They are then shipped to india where they are processed in factories. The indian suppliers make antibiotics for Global Market few people know they export to leading german companies. Even if the antibiotics are only packaged and controlled in germany the companies can label them as made in germany. The results of our samples are in. Professor zirkle tested them for seventeen different antibiotics some samples contain high levels of antibiotics including ones taken in the lake and the musi river. One sample was taken in a sewage pipe right outside an m. S. N. Factory. The Company Claims to be so environmentally friendly in its commercials yet here the level of antibiotics was five thousand five hundred times higher than the approved level. Here we have a high level of moxie fluxus in an antibiotic that is very stable it is almost impossible to degrade it this is a considerably high level of. The higher the concentration of around about x. The more multi resistant pathogens were found as the growth of the multi resistant pathogens explodes the effect is like a catapult. Effect its going to we could say the samples were taken in india and thats a long way away bad enough but how does it affect us. As. It has a lot to do with us we have decided as a result of globalization to use in the purest sense of the word with dirty export methods. Because manpower is cheaper and buildings and Technology May be cheaper there too. And were really importing the problem that we have extorted by importing resistant microorganisms through tourism air freight and so on. We want as we go to work because of the long run but they reach patients in our hospitals and its much more difficult for us to treat them than was the case in the past. When via this all can we allow this to continue without intervening it will become a time bomb between all it already is because what weve found here is a huge received. From. Many major german Pharma Companies by products in hyderabad we repeatedly asked for interviews but no one agrees to one in writing they all agree that this is a serious problem but no one will assume responsibility. Xcel says it is the only company that still produces a large percentage of its antibiotics in europe and the same standards applied to their products from india. And starter also refer to stringent guidelines and regular quality checks but the Pharma Companies refused to comment on why we find such high levels of antibiotic waste near the factories. Colgan etiquette is staging a spring party. The association represents almost all the companies that sell antibiotics. One Association Member tells us off camera that the medical Insurance Companies only pay for the cheapest medication. But Environmental Standards are supposed to be part of the control mechanisms. This is a task for the politicians but no one is prepared to assume responsibility. Theres responsibilities for the big formal that volley these products they will. Hold the power to to affect the production process by putting down from there some contractors but there was also responsibility with those who have the power to regulate and control this they stop just. For example cameron conclude that Germanys Health minister wants the same rules to apply in india as in europe the topic for the recent g. Twenty summit in hamburg he knows time is of the essence. Of the father and the fire danger is caused by antibiotic resistance or being ignored its an approaching disaster and the danger is we dont take it seriously enough. Dilute it is calling on the ministry of the environment to ensure control mechanisms in india the Health Ministry only has an advisory role. Via how. We are carrying out our own research to establish the link between sewerage and resistance. Im convinced that we need to introduce more standards to regulate at a biotech resistance of the first of. A but we have not made any demand seattle or put pressure on other e. U. Nations. You describe yes to my first well discuss this with the g. Twenty nations we dont want to pressure them but rather win them over. If we try to lay down the law to them we wont solve the problems. Everyone agrees its a serious problem but who will solve it and until it is solved german Pharma Companies will continue to have their products made in india in the same way and they will continue to play a part in producing deadly pathogens but i think we should. See where. Are my drugs produce who is producing my drugs under what conditions or my god produced. This most club must be aware of the dangerous. Missing him we must see the Collateral Damage occurring there and exert pressure to get things changed just because we can stop it im upset in. The end call a cattle of uganda theyre an important Food Resource and better for the environment than other cattle. But now the indigenous ferocity is being replaced by more productive but less resilient holsteins. Environmentalist and attrition s. Are joining forces to stop it. Go at africa thirty minutes till you. Are black our fighters want to start families to become farmers or engineers every one of them has a plan of the initial for your children so nothing is just on the children who have already been the lawyer and those that will follow are part of a new class us. They could be the future of. Granting opportunities for global news that matters d. W. Made some minds. Looking for the white house. Around this take you know about the top of your favorite. Electability not to make the point that much it took you and your politics in the entire country championing insurance for the last sixty years. For minds. This is g. W. News live from berlin u. S. President donald trump clashes with allies over trade at the g. Seven summit he condemns unfair trade practices and then proposes removing all tariffs and barriers to trade for g Seven Members will go live to a press conference with canadian Prime Minister has just entered the. Twitter welcome to the program