headed here now, that there will be a recommendation for the most vulnerable to get a booster? >> i think so, you know, we have had this discussion before, jim, we said that the two mrna vaccines will be three dose vaccines and joinhnson & johnso will be a two-dose vaccine. i said that early on where it showed that individuals who got two doses of the j&j vaccine had much higher levels of virus neutralizing antibody and more robust t-cell responses. and i think that's what's panning out. there was some discussion a couple of days ago about a preprint that came online suggesting that those who got a j&j dose of this irvaccine when they were -- when they got boosted with mrna vaccines they did better than a second j&j dose. i'm pushing back a little bit on that in the sense that when you look at that early data, the big rise in responses were delayed happened later on, maybe 70, 80