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protection against severe disease, significant is the word that dr. alex seigel, the researcher in south africa, that's the word he use wednesday me when i spoke -- used with me when i spoke to him. he thinks that two doses will give significant protection against severe disease. but it's very clear from the pfizer data that the third dose may give more robust protection. so i think what this has a lot of people asking is, well, is this basically a three-dose vaccine? is this a vaccine like many other vaccines that ought to be given in three doses? so our colleague, kate bolduan, had a discussion about this earlier with dr. anthony fauci. >> i don't see that changing tomorrow or next week. but certainly if you want to talk about what optimal protection is, i don't think anybody would argue that optimal protection is going to be with the third shot. whether or not it officially gets changed in the definition, i think that's going to be considered literally on a daily basis. that's always on the table. it's going to be a matter of

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