yellowing of the skin or eyes, dark urine, tiredness, loss of appetite, abdomen pain, bleeding, bruising, fever, chills, or other symptoms of an infection, a severe or worsening rash, are or plan to become pregnant, or breastfeeding. avoid grapefruit during treatment. kisqali is not approved for use with tamoxifen. it's our time. for more time. we asked for kisqali. ask your doctor about living longer with kisqali. with less moderate-to-severe eczema why hide your skin