opdivo can cause your immune system to attack normal organs and tissues in your body and affect how they work. this may happen any time during or after treatment has ended, and may become serious and lead to death. see your doctor right away if you experience new or worsening cough; chest pain; shortness of breath; diarrhea; severe stomach pain or tenderness; severe nausea or vomiting; loss of appetite;... ...swollen ankles; extreme fatigue; constipation; rash; or muscle or joint pain, as this may keep these problems from becoming more serious. these are not all the possible side effects of opdivo. tell your doctor about all your medical conditions including immune system problems or if you've had an organ transplant, or lung, breathing or liver problems. a chance to live longer. ask your doctor if opdivo is right for you. bristol-myers squibb thanks the patients and physicians who participated in the opdivo clinical trial. count on being slammed this hwith orders. we're getting slammed with orders. and my customers knowing right when their packages arrive.