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S p declining 0. 08 and the nasdaq advancing 0. 02 , we had them all. We need to do an autopsy to make sure we have the right cause of both the advances and the selloffs. So lets examine the cross currents. You know ive been saying that there will be some days where some Republican Leaders try to slow the trump agenda. Take apart the tripod that this rally rests on, a speedy end to regulation, fast repatriation of foreign money and Corporate Tax reform. In the last 24 hours, the gop Alliance Trump needs to move fast on the tripod of reforms, the ones that have helped stocks immensely, is showing some signs of fracturing. First the heavy focus on repealing obamacare is shoving the tax reform out of the picture, scrapping the Affordable Care act could make the economy grow faster. Not denying that. But its not really part of the stock propulsion program. And, yes, i am being a little facetious, but this is mad money. Its never going to be mad politics. Second, the Senate Hearings today about Cyber Espionage also showed that some senators are not afraid of defying trump. When you hold big haergz that seem to question the bona fides of what some are calling trumps real politic position on moscow, you now there are some like john mccain who want to show independence from the new president , the president elect. Trump isnt going to pick up any democratic help by calling minority leader chuck sumer the head clown of the senate. When Ronald Reagan wanted the other side of the aisle on board, that meant he wanted to share a beer with head democrat tip oneill. Get something done. Reagan had a huge electoral mandate. Trump won an incredibly close nail biter. Chuck schumer could potentially be an ally on repatriation, so maybe calling him a clown isnt the most effective way to get things done. The result, if trumps own party is going to make trouble for that agenda, the one that brought us oh so close to dow 20,000, then were going to have a downturn like today for any company that, lets say is trump stock. A trump stock. Third, i always tell you you have to take a cue from the bond market. Bond yields went down today. Interest rates down. This stock market rally has been helped immensely by a belief that the economy is actually getting stronger, a judgment backed up by the recent rise in Interest Rates. But we had a weaker than expected adp payroll number this morning, and thats causing people to wonder whether maybe theres a bit of a slowdown going on, something thats out of sync with whats supposed to be happening as companies anticipate trumps incredibly probusiness agenda. Could there be a pause going here . Could there be a pause before the growth starts . The bank stocks need Interest Rates higher. Theyve been leaders. When Interest Rates naturally fall as they did today, the banks get sold off. Sell, sell, sell. Theyre a powerful component of the trump rally. You cant lose the banks and expect upward momentum. Maybe this rebound in bond prices, which pushes these yields lower, maybe its an outlier. Dont know yet. Lets complicate things even more negatively. If trump loses key republican legislators and we have a slower economy, maybe that means less deregulation and less lending. That is suboptimal. Plus this turned out to be how do i put it a bad trump tweet day. The president elect blasted toyota for wanting to build a plant in baja, mexico, that could export cars to the u. S. Trump tweeted that toyota is courting a border tax. Thats not what you want to hear if your consteplation brands which imports beer from mexico. After reporting a fine quarter, the stock plummeted 11 points. Ill have to speak to mr. Sands, ceo of constellation, later in the show. Lets throw in a real round house. The collapse of earnings from brick and mortar retailers, macys and kohls, both of which just gave up the ghost and revealed a shocking decline in sales. Ma macys stock dropped. Kohls cole, down 19 . When you include negative numbers victorias secret down 4, there are only two conclusions. Either the consumer has no appetite for spending at all or no appetite for traditional mallbased retailers. Heres an amazing wrinkle that ties everything up. When the news about the downfall of macys and kohls came out, all retailers initially got crushed. But as the smoke cleared, we saw a grudging recognition that perhaps its not the consumer thats taking a breather from spending. After all, just yesterday we had huge auto sales. That puts the lie to that thesis. Its just that the consumer has simply had it with the mall. So amazon, which was unsteady at the beginning of the day, started really galloping by 9 45 and ultimately closed up more than 23 bucks. Hallelujah. Now, i want you to think about something that mark z zuckerberg has taught us. He emphasizes it again and again on the conference calls. He says that younger facebook users hate idol time. They like to do as many things as possible at once, yes, multi tasking. So now extrapolate. If these kids are shopping online instead of going to the mall, then they arent just shopping. Theyre Comparison Shopping and reviewing on google as they check their facebook and instagram feeds or watch movies on netflix. In short, the add generation is fanging. It gets better. When the economy is slowing and its not a trump day, you can go back to buying the stocks of companies that do well in a slowdown, the ones that dont need trumps help. You know what im talking about. Yes, facebook, amazon, netflix, and alphabet, nee google. Hence the nasdaqs all time high. The trump rally may have taken a breather. But the fang rally, its back on. It was so powerful, it went all the way down the food chain to the actual device people use to connect to the internet. Thats right, the pin action boosted the stock of apple, which revealed that its App Store Developers raked in 20 billion in 2016. Thats up 40 yearoveryear. That means the stream of revenue im most excited about for apple, the Service Stream that can help the company diversify might be growing faster than expected. Why else would they release this number . I like it. So did the market. I think the bears on apple, i think theyre starting to lose patience. The stock could be breaking out. What else makes for good internet presentation . You need adobe to get the job done. We own adobe for the Charitable Trust. Telling actionalertsplus. Com club members, buy it aggressively. Its finally beginning to take off after that beautiful quarter. Now, back to the concept of whether today is an outlier or not. Is this a oneoff rotation, or are we about to revert to the days when only a handful of High Growth Companies can do well . Two observations. If trump signals that its time to start cutting deals fast to bring back the progrowth tripod, then the money flows back to the group. Second, the fact is the money is mostly staying in the market. Its actually bullish in and of itself. We dont want the same stocks going up over and over and over again on no new news like we have recently with the airlines. They moved up endlessly on the same pieces of data, and thats whats known as multiple expansion. Thats the kind of advance i dont like. See, i want to pay more for higher earning streams, not for the same earnings streams. So im not as perturbed by todays rotation as i otherwise would be. Lets put it all together in one package. When you have a bad trump day combined with a series of weaker data points from brick and mortar details that cause rates to fall, you see money quickly flow out of the new winners and back into the old winners, the companies that make your life easier, the ones that the millennials love. Put another way, in a bear market, when the central thesis wavers, in this case, the trump tri pod of deregulation, repatriation and lower taxes, everything goes down. But in a good market like this, the money just rolls on over into neglected sectors that are hungry for recognition. The bottom line of this coroners inquest, this is the pause that ive been expecting. I cant run away from it. Its just rather than unleashing a tsunami of selling, its merely caused money to flow from trump stock. To not a trump stock. The jury is still out on how long we go trump. But at least we arent going no stock. Remegio in missouri. Caller yes, jim, booyah. Booyah. Caller thank you very much for taking my call. Ive got a question. My question is on mobileye. What do you think about this stock in 2017 . Well, you know, mobileye is kind of one of these players in this autonomous drive, and i think when you think about those, you might want to start looking again at the stock thats been pulling back and pulling back hard for the last ten days. Yes, talk about nvidia. I feel more comfortable with that one or nxpi, which is being bought by qualcomm. Those are better plays. Peter in texas, peter. Caller hi, cramer. Happy new year from texas. Oh, thank you so much. We got the super bowl coming down there. Caller yep, right here in tus ton. I want to know what youre currently thinking about black stone. I got three specific questions. I love the leadership. I love the dividend, and i like what theyre doing in commercial real estate. I was watching it. Suddenly theyre up 12 just this week. Is it too expensive now . No, no. Its finally getting the nushl support it deserves, peter. I felt like that this is a situation where if you had a better stock market, then people would realize that black stone can do more things and liquify some of its assets. Its a very good market. I have stood by Steven Schwartzman not just because hes from the tone just over from me in philadelphia, but because the company is run by a lot of smart people. Some days are confusing but im here to help you figure them out. I think its a pause, a transition to not trump stocks. At least were not in a nostock zone like we would have been before trump was elected. On mad money tonight, with the inauguration a little over two weeks away, im sitting down with the ceo of box to see what technological changes hes anticipating. Then talk about a retail wreck. Macys and kohls crushed. Gap surprised with good ones. Now im going to tell you why its pointing to a bigger issue in the industry. And Constellation Brands reported earnings today, and the report looked festive with better than expected numbers. But the stock still has a hangover. Ill get to the bottom of the decline with the ceo. So stick with cramer. Announcer dont miss a second of mad money. Follow jimcramer on twitter. Have a question . Tweet cramer, madtweets. Send jim an email to madmoney cnbc. Com or give us a call at 1800743cnbc. Miss something . Head to madmoney. Cnbc. Com. Did you know slow internet can actually hold your business back . Say goodbye to slow downloads, slow backups, slow everything. Comcast business offers blazing fast and reliable internet thats over 6 times faster than slow internet from the phone company. Say hello to internet speeds up to 250 mbps. And add phone and tv for only 34. 90 more a month. Call today. Comcast business. Built for business. Since the election, investors have been so excited about the companies that do better in an accelerated economy that aside from a few very high profile examples, they pretty much ignored the good things happening at the kind of secular Growth Companies that get less of a boost from faster gdp growth, which is exactly what this market is expecting from trumps agenda. Let me give you an example, a Company Called box. Its a storage provider slash mobile business collaborative platform. They reported a terrific quarter at the end of november. Raised its full year guidance for 2017. Looks pretty close to profitability. Its got a giant Customer Base with 31 million users, growing sales at a 31 clip. While its still not profitable, thats because they prefer to invest. Doesnt that sound salesforce. Com . Since box reported that Strong Quarter a little more than a month ago, its stock has actually come down more than 4 even as the Broader Market rocketed higher. Box is now trading at 14 and change, only a few nickels and dimes from where it came public a few years ago at 14 bucks even. So is this a buyable pullback or do we need to be concerned that the wall street fashion show may have turned its back on this kind of stock . Lets take a closer look with aaron levy. Hes the cofounder, chairman, and ceo of box, to learn more about how his company is doing and where its headed. Aaron, welcome back to the show. Thanks for having me. It was a breakout quarter. You did more than 100 million in revenues. Thats a praj etrajectory we wa. Youve got a lot of customers. We know the market seems to like these companies that benefit from a trump agenda. What does box do to be able to participate in that, or does it just keep doing its own thing and hope one day people recognize it . Well, i think, you know, irrespective of a trump agenda for a second, if you think about how complex is the world is getting for businesses, there is an increase in cybersecurity threats. Theres a tremendous amount of regulation that businesses have to deal with. Theres global collaboration issues. So when you think about all of that complexity, we provide a platform that simplifies how companies can work, share, and collaborate on their information in a very secure way. So weve seen growth under, you know, lots of different types of administrations, and we believe that were on a trajectory to continue to grow rapidly in the future. Ive read through a lot of interviews that people have had with you. The one thing that weve lacked is an example of why box has a customer, what the customer wants from box, how box got it, and why that customer is not anxious to shift to a competitor. Could you walk me through an example . Sure. So we have 69,000 customers globally. Were definitely the biggest platform in this space serving enterprises. Were in 63 of the fortune 500. So Companies Like pfizer, general electric, and many others use box. One great example is a company like as tra zen ca. So a global pharmaceutical company. When you think about how much data they have to manage and share across everything from r, and d teams to Marketing Teams to sales and finance. They have tremendous amounts of data across their tens of thousands of employees, and they ref language back to be able to securely manage that information and allow their employees to be able to collaborate with vendors all across the world. Were the only company that can do that in a very secure fashion while assuring end users get a great experience at the same time. So were going after a 30 to 40 billion market that is moving from legacy systems to the cloud, just like salesforce. Com took over legacy crm companies. Were doing the same thing in content management and collaboration. So lets say youve got google partnership, ibm as a partnership. Lets take oracle. They decide, you know what, were going to turn off the oxygen. How do we know that they dont look at box and say, you know what, we came after workday. Weve been winning. We are going to own boxs space. What makes it so Larry Ellison cant just say box is done . Well, you know, weve been in this space now over 11 years. We built the only platform that can scale to meet the Worlds Largest organizations as well as the end user use cases that we go after. Thats not necessarily the strong suit of traditional Enterprise Software companies. Further, we actually partner with most of the traditional incumbents in this market. We have an incredible partnership with ibm, with microsoft. We partner with google. So we would hope to do the same thing with oracle, to be able to integrate across their erp system and some of their other modern applications. We would actually see oracle over time as more of a complementary platform that we can integrate with as opposed to a competitor. Sometimes i worry when you show profitability, which could be only a quarter or two away, or at least Free Cash Flow positive in a way that could be explosive, if i were ibm, if i were google, the stock stays 12, 13, 14, i bid 16. I say aaron, nice to meet you, and youve got a sell. We believe were going after a pretty massive industry, and we would think that 16 as an example would dramatically underrepresent the opportunity that we have in front of us. So were certainly, you know, really shooting for the stars on this one, and this is our mission is to dominate this industry by building the only platform that can serve every enterprise on the planet. So we have a large amount of growth ahead of us that were very, very confident were going to be able to achieve. All right. In the last minute i have, you have a very active blogger, and you did Say Something in your postelection memo to employers. Im hopeful over the coming weeks and months, well start to see a very different style from the president elect. Some of the ideas that were pros in the Campaign Cycle would be disastrous and im confident they will not come to pass. So far this president elect has been pretty true to the campaign president. Should we be more concerned if we work in hightech, if we work at box, if were Business People . What do you say . Well, that was especially that note was especially specifically referring to many of the social issues that we care about as a company and really being able to drive a community that can create innovation, you know, going forward. I think that so far we havent seen anything at a policy level that would be challenging to innovation and innovative companies. Obviously trump welcomed in a number of tech leaders that i think they had a Good Exchange around what the future could look like. But we are paying very close attention to certainly the situation. We do want to find constructive ways to work with the new administration. But in general theres no stopping the amount of progress and the amount of innovation thats happening in the future, and our job at box is to make sure that we build a platform that can really serve every enterprise on the planet going forward. I should ask this because facebook is flying today. Working there, facebook, enterprise, sound like Something Big . Yeah. So they have a new product called workplace by facebook, and its exactly what youd imagine it to be. Its a version of facebook that works in the enterprise so you can communicate and connect to coworkers and employees. We are partnering with facebook to deliver content and the files that are stored in box securely in the facebook environment. So as more and more applications start entering the enterprise in the future, cloud applications, box is going to be the central back end for managing the content and the files that then link into those applications. So no matter how fragmented an i. T. Environment gets in the future, customers can have one single place to be able to manage their information. Thats our value proposition, and thats why we have 69,000 customers on the platform. Ive been thinking that the stock at 1. 8 billion makes no sense. It should be much bigger. I always love to see you because youve got a great vision. I love you. Cofounder and ceo of box. Good to see you, sir. Look, 14, i dont know. I mean i think theres a lot good here thats not reflected in a 14 stock. Mad money is back after the break. Announcer after the break, cramer picks his poison with the ceo of Constellation Brands. The stocks got a hangover even after todays earnings beat. What will it take for the shares to get back in high spirits . Find out when mad money comes back. You want to understand the implosions of macys, down close to 14 today, kohls down nearly 20 , you need some context, the kind i can provide because ive been steeped in retail my entire life. My mother worked at lits. My father works as gym bes. Mom sold lingerie. Pop sold mens slacks. They succumbed years ago, victims of better competitors nobody saw coming. So when i read these stories about macys and kohls, i thought about gym balances and lits, and how the landscape is a war of all against all with the life of even the most hallowed business often turns out to be nasty, brutish and short. I grew up in retail. I remember going to store after store with pop who was hawking boxes and bags to retailers, hoping to sell them gift wrap or personalized nameplated shopping bags. He went into this business after gym balances let him go. We used to marvel that so many of the customers, these little mom and pop retailers would go understand right after he advanced them credit to buy bags that were now worthless because they had a defunct merchants name emplacened on them. Why did these companies go under . They got steamrolled by woolworths, kmart. The amazing big box bargain centers, all these except kmart were done in by a better group of stores, namely walmart. The circle just keeps turning. Now walmart and target are the ones trying to stay relevant in the face of fierce competition from the web. So when if comes to macys and kohls, we do need to get existential. What is the reason for being . Sure, macys is the Third Largest online seller in its categories after amazon and walmart, but that doesnt pay the rent. Kohls has some terrific bargains. I wear it. But when i read the stories last night, i had to wonder does anyone like going to these places anymore because i sure dont. Its cliche, but i too would rather go to amazon or frankly to the Boutique Stores in the short hills mall down the block from me that cost a fortune. But they know my name. They know my wifes name. They know what she wants. They know her sizes. It makes life easier for me. Ill screw it up if i go to amazon for that stuff. Now, there is still room for these ultraspecialty kinds of retailers, but thats because the 1 have to shop elsewhere. Yes, im lucky enough, thank you. Even the really rich dont like to shell out 10 grand for a pair of paul morelli earnings without seeing them in person, which brings me to a particular point about the mall. The mall isnt dead. The malls rents are too expensive for all but the most exclusive specialty retailers. Mass merchandise, though, even higher end mass merchandise like youd see at sacs or Neiman Marcus just doesnt cut it, largely because if you know your size, you can just buy the stuff from their websites or from amazon. Again, doesnt pay the rent. Whats incredible is the speed with which this is all happening. Macys had its best Holiday Season ever just two years ago and now theyre doing terribly. It looks like the plan to close stores might not be enough. I got to hand it to my late pop. He saw all this coming when walmart started selling clothes for less than what the small merchandise he was selling to had to pay in order to buy the same merchandise. He stopped catering to his rapidly dwindling mom and pop clients and started selling name plated doggy bags to expensive restaurants. This was his last order, because he knew that philadelphians would never spend a lot of money on a meal and not want to take home the leftovers. Philadelphians were too cheap. Now, everyone is too cheap to shop at the mall. Its just too inconvenient unless youre uber wealthy and need to see the wares in person before buying them. If macys and kohls havent figured that out yet, maybe theres no solution. Then again, the mom and pop cavalry couldnt figure out what to do with the Department Store tanks. And now the tanks are right out in the open, just waiting for the jetpowered amazon to carpet bomb them. Tre in florida, tre. Caller booyah from the sunshine state, cramer. Nice. Whats happening . Caller i got a question for you. Ive been listening to your warnings about retail and to stay away from the whole sector in general. But ive been watching express, Ticker Symbol extr. Fundamentals look pretty good. Theyre sitting right off of their 52week low. Right. Caller im wondering if you think this could be a chance. Tre, when i was at the mall recently, i took a picture of express because i was ai maed there was no one there. I just felt so bad for the guys, i didnt post it on twitter. You need customers. In the end, pop taught me that. Its not enough to have the merchandise. They got to get the customers. I say stay away. Art in tennessee, art. Caller good evening, dr. Cramer. I think youre a noble successor to the great louis rue kaiser. Im curious about lands end. Its been wandering in red ink for several quarters. However, it has a new ceo, and it also won a large Delta Airlines uniform contract. Ive seen some of those new delta uniforms being tested, and they look really sharp. Is this a purely speculative specialty retailer play, or is this a way to benefit from organic Airline Industry growth . You know what, ive been looking at lands end and i think you have to mutt togethpua couple quarters. I know they do have good management. I think they have strong people on the board. Im not against it, but i dont like retail. I mean i like amazon, so lands end, i say maybe i can go on amazon and get some lands end stuff. Kohls and macys are in a retail rut, and sadly maybe theres no solution. Much more mad money ahead today. That drop in Constellation Brands, did it make you feel like you need a stiff modelo . Im talking to the ceo to see if theres an opportunity to buy. Then there was a halo today. While the major averages declined, the Company Ended the day up 20 on some positive data. Ill tell you if the healty gains will continue. And of course, all your calls rapid fire in tonights edition of the lightning round. So stay with cramer. We spent a lot of time talking about all the potential winners from the Incoming Trump administration. But on a down day for the industrials, its good to remember there are some real potential losers too. Im not talking about the companies he goes after on twitter. We know the president elect is thinking about trying to impose some kind of cross border tax on imports. Witness how trump just tweeted that he hit toyota with a big border tax if they build a new plant in mexico instead of here. And toyota is not even an american company. How worry the does this make investors . Just take one look at Constellation Brands, stz, the terrific Alcohol Company thats the Worlds Largest purveyor of premium wines. Ive liked constellation for ages because a few years ago they managed to acquire the u. S. Rights to corona, modelo, pa saskco, the worlds most popular mexican beers. But this is exactly the kind of business that could be punished by an import tax. Constellation just reported a good looking quarter today. 24 cent earnings beat. Inline revenues, but the stock got slammed, down 10 bucks. Perhaps its because management didnt necessarily give you the kind of clarity that you need about trumps impulses or also Goldman Sachs said this things that maybe the quarter wasnt as strong as it looked. Not clear. But i do know this. This is a stock that has gone up from 35 to 140 in a very short period of time, and thats what may be at work here. Profit taking. How worried should we be . Its a great company, but some people think it is not the kind of stock to own at this moment. Thats why we need to check in with rob sands, president and ceo of Constellation Brands to learn more about the quarter and the possible damage that an import tax could do to his business. Mr. Sands, welcome back to mad money. Thanks, jim. How are you . How do you make a mexican beer in america . In the end, arent there some companies that just theres nothing you can do . If youre making a mexican beer, you cant make it in colorado. Well, thats true, jim. But that said, as you noted, we had a fantastic quarter. I mean just blew away everything almost in every regard. Fantastic sales results. But there is a lot of volatility in our stock as a consequence of the aspects of tax reform regarding the border adjustability tax that you mentioned. So i think that is probably what we can attribute the volatility today towards. Rob, youre a man who puts his money where his mouth is. Now, you did spend a huge amount of time talking about it. You didnt duck it at all. But you also spent a lot of time talking about buying back your own stock, which indicates to me you take a longer term view. Well, absolutely. You know, we did note that over the last couple of quarters, we purchased over 800 million of our own stock. Thats because we clearly think that its undervalued, and weve done a lot of work on the socalled border tax or border adju adjustability. We think theres plenty of mitigating factors, either things we can do or things that will in fact mitigate the tax, which makes it such that we believe that we can meet our midand longterm guidance of doubledigit eps growth. So were extremely confident that no matter what the outcome of that is, that were going to be able to achieve our goals. So we put our money where our mouth is, and were buying back our stock. All right. So lets say president elect trump tweets, saw sands on cram cramers mad money. That guy should be bottling his beer in the u. S. And using natural gas. What do you say . Well, what i would say about that is it cant be bottled or made in the u. S. Because its not its not a u. S. Product. Its an inherently mexican product. But that said, you know, the whole border adjustability concept is about not being able to deduct foreignsourced work in process and raw materials. So we have the capability of shifting a lot of our either work in process or raw materials, things like natural gas to u. S. Sourced and increase the percentage of those items and therefore increase the percentage of cost of goods sold that would be deductible. I think thats pretty aligned with whats trying to be accomplished by the Trump Administration and the republicans. All right. One of the things that happened so we feel good about our position. I did too. But then i felt you answered a lot of those questions great on the call, and then a Goldman Sachs analyst of some note, who ive known for years, suddenly throws a Monkey Wrench in and said beer wasnt that good and its he slowing. I can raid numbers. You can read numbers. I didnt see that in the quarter. Trying to figure out how the confusion came about. So what judy of goldman, and shes great, is talking about is the fact that our mexican beer depletion, sales to retail, fundamentally our sales were up 10. 7 following last quarter, where they were up about 14 . Okay. So perhaps that was perceived as a slight slowdown. But that said, last quarter we were overlapping a quarter of the Previous Year where our sales were up 10 whereas Third Quarter or this quarter last year, our sales were up 16 . Rob, one last thing before i let you go. You guys are constantly innovating. Youre constantly getting new labels. I have a highend casa know play on my desk here, a tequila. I know youve done this with highend whiskeys. Youre not getting enough credit, in my opinion, for the innovation youre bringing to an industry that hasnt had innovation in a hundred years. I want to give you a minute to talk about the new stuff you brought out. Yeah, weve got lots of great new stuff, jim. The tequila that you mentioned that youve got there, which we age in Robert Mondavi barrels. We recently acquired one of the whiskey, bourbon and rye distillers, named whiskey producer of the year by whiskey advocate magazine. We just purchased a new brand called charles smith, and their kung fu panda reese ling made the top 100 in wine spectator. Were innovating new products like the tequila that you have all the time. So lots of great new stuff in our portfolio. Well, its terrific, rob. I know the confusion. Youre, uf always played it straight out with us. But remember the stock has quadrupled and maybe sometimes people want to take profits. Good to see you, sir. Yes, thank you. This one, you wait till it settles, okay . You wait till these people give up on it and you get your opportunity. Thats happening right now. Mad money is back after the break. Announcer lightning round is sponsored by td ameritrade. It is time it is time for the lightning round on cramers mad money. Thats where i take your calls rapid fire. You tell me the name of the stock. I tell you to buy, buy, buy or sell, sell, sell. Well play this sound [ buzzer ] and then the lightning round is over. Are you ready, skeedaddy . Its time for the lightning round on cramers mad money. Im going to start with bart in texas, bart. Caller theres an old song called jim dandy to the rescue, and my rescue is vodafone. I like vodafone. I have to tell you ive warmed up to a lot of i like Credit Suisse by the way. I like barclays. Im going to put that in as part of my european basket. Lets go to james in connecticut, james. Caller hey, cramer. Thanks for all the great advice over the years. My wife really loves you. Im calling you about u. S. Silica. Im not going to buy the sands stocks. Theres not enough what i regard as being theyre too commodity. My Charitable Trust owns schlumberger. Its time to own the best. Rob in florida, rob. Caller yeah, james. This is rob in florida. I got a twopart question. Twopart. Caller on encanna, the oil outfit. Do you think its worth a buy . Yeah, i like encana. You know why . Because encana just raised its production guidance. Ive been waiting for that to happen. I always like it because they pronounce it like if youre from philadelphia. Their production going up. Encana is for me. Lets go to javon in pennsylvania. Caller hey, whats going on, jim . Not much. How about you . Caller im doing fantastic. Calling from your hometown of philly. I wanted to know what you think about arconic. I think arconic is right. When i saw those auto sales the other day, when i think about the fact that airplane business, thats another big part of the business is good, gas turbine business is good. Bottle, canning, just okay. But i happen to think that arconic remember, its the old alcoa. I think arconic is going to be a winner, which is why my Charitable Trust continues to buy the stock, and we suggested to club members just yesterday, it is time. How about kim in pennsylvania, kim. Caller hey, jim. Big booyah from pittsburgh, pennsylvania. City of winners. A city i wish i were born in. You got so many i was born in philadelphia. Luck of the draw. Caller you should have came here now, jim. The whole things been wrong. Go ahead. Caller anyway, i received avan six, a spinoff from honeywell, and it seems to be gaining some momentum here. Where do you think this stock is going . The resin business is good. It was always a Good Business and just didnt fit into what dave cote wanted to have. I want you to hold on to that stock. And that, ladies and gentlemen, is the conclusion of the lightning round [ buzzer ] announcer the lightning round is sponsored by td ameritrade. Sy r evg s tt. Kis a nara adts crusm fofoalththin. Ern hit all . Lt atrethonta ghgh t. Adts crusm fofoalththin n thes hi ern hit all . Lt atretonlyad ing i ere, in hiis stuffma steso ,yoinanceuruthdoou ss . N n thes hi ern hit all . Lt atyou partthsernnts ing i e rte 0, div i pn so the biotech cohort has been under pressure as we dont really know what the Trump Administrations attitude toward the drug industry would look like. Today we got positive outlook from hal oh zooim thurps. A biotech focused on using human enzymes. Its an area outside your bodys cells that among other things provide some structural support for your bodys various tissues. Their toj can help deliver drugs more efficiently. They reported some very strong results for their faphase two advanced pancreatic drug. Right now there arent a lot of options if you get this awful disease. This isnt just a one trick pony. They already have one therapy on the market thats designed to help your body absorb other medications and a host of partnerships with larger Drug Companies to use their Drug Delivery platform. The stock surged nearly 18 today or close to 2 bucks. While thats down from the initial gain, there was some chatter the results werent quite as strong as they seem. Lets dig deeper with the president and ceo to find out more about her company and where it is headed. Doctor, welcome back to mad money. Good to see you. Thank you so much. Please just walk us through. What does this mornings announcement mean for your lead therapy, pegph 20, and what do the results show . Thank you. Well, today we announced, as you say, the results of our phase two study, looking at peg ph 20 and patients with advanced pancreas cancer. Just as a reminder, pancreas cancer is one of the most devastating cancers still today. If you have advanced cancer, the probability of survival at five years is less than 5 . So what we reported today was positive results. In terms of the two primary end points of the study, we met them. The first one was the ability to improve the time to progression in patients receiving our drug, and that was a statistically significant change. We also reduced the rate of blood clots in the patients receiving peg ph 20. But i think where most people have wanted to focus, and were being very excited by the data is to look at patients who have got high levels of a sugar around their tumor. In those patients in a subset of this study which we call stage two and this is important because this is the population that is most similar to the population were studying in phase three. In those particular patients, we were able to see when peg ph 20 was added to todays standard of care, these patients had a 91 improvement in the progressionFree Survival and a 50 improvement if their overall survival. This is a biomarker that were developing and want to test, and we actually are using it in our phase three study. Doctor, one of the things i like to bring up because weve learned to be somewhat skeptical on biotech because it doesnt always work out. Tonight amgen won a big verdict blogging regenerons drug. Theres a lot of competition. Is it possible some people could view that ill use a term that i saw on the web, that you cherry picked data points that made the results look better. Or is it just such a terrible disease that anything you can do is better than what we have as the current standard of care and thats what we should be focused on . Our phase two study is a large, welldesigned and controlled phase two study of over 250 patients. What weve presented today was a conservative review of all of the study populations looking at the key efficacy end points of progression Free Survival and overall survival. There was a good consistency. In the overall data, particular lit with regards to progressionFree Survival. Now, overall survival was a secondary end point and an exploratory end point. I mentioned we saw the 50 improvement in overall survival in the stage two patients who had high levels of the sugar. When we actually look at the overall population, we didnt see a benefit. And theres a number of reasons for that, including if you recall, jim, when we did stage one of the study, we had a temporary clinical hold that may have impacted it. But i think whats the Important Message is that this data is certainly supportive. All of the confirm tory phase three study that we have already under way, and that is really what its to do. Its to help you, do you have your design right, your powering right. Do you have the biomarker marker right . All of this, the data is supportive of, and well continue to evaluate the data and take learnings from. But we certainly feel very good that this data supports our actions in our phase three study. I like to think thats not your only product. You have won approved which is high la next. Can you quantify how that therapy has grown since it was launched . Yes. This is a product that, as you mentioned, is useds aa spreading agent. Its mostly using in opthalmic surgery. Its in the range of 15 million a year, but it does help patients. Okay. And then finally for the drug weve mostly been talking about, when do you expect data from phase three because i know that there will be people out there watching the show who know loved ones or people who have it and say, look, well try anything. Can we get on this drug . So we do have our phase three study ongoing. Its going to explore 420 patients with high levels of this sugar. Its at 200 centers around the world. We enrolled the first patient in march of 2016, and we really are still in our enrollment ramp, so its probably premature to comment on exactly when well have the data. But i can assure you the entire halo zooim team is working hard to get this product to patients as quickly as we can pending obviously positive data. Thank you so much. Exploring still one more way to be able to deal with diseases that were always fatal just a few years ago. Speculative stock. We know all the risks of biotech. Youve heard the pluses and the negatives, and all i can say is, look, if you want to speculate, halozyme is a speculative. Stick with cramer. Uioks oddneyey hass ac s. Ne d q i like to say theres always a bull market somewhere, and i promise to try to find it just for you right here on mad money. Im jim cramer. See you tomorrow. Smells great. Mcgraw diggin ditches. Its all in a days work. When youre a millionaire. theme music playing these folks invest in hedge trimmers, not hedge funds. They turned diy into roi. And thanks to hard work, incredible passion, and a whole lotta mud, sweat and tears, they turned their dirty jobs into filthy riches. Time to go make some money horn honking mcgraw tonight, a quirky Telecom Titan who went from laying cable to livin la vida loca. A struggling secretary who did one good deed and found herself the owner of a multimillion dollar company. God, i love the smell of fresh asphalt

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