of proper global engagement on this public health issue, if nothing else? there has been more movement on global treaties than you might think. in some corners on fish, on, to some extent, on climate change. i think this one will be more done in bits and pieces, but i do think there is a lot of impetus there for it to be done, whether out of naked self—interest as countries realise that they are vulnerable until the whole world is safer, or out of philanthropy and generosity. but i think if not as grandly formed as a great global treaty, there will be a lot more international effort on this than there has been. marc, what about europe in 2022? it's a vast continent — 50—odd — 50—plus countries, at least as far as the world health organization defines it — i think nearly 58 countries it counts as european beyond just the european union — but a very kind of mixed picture in europe, isn't it, in terms of notjust dealing with covid, but the challenges the continent faces? well, the big challenges are,