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Well look ahead to a really important night for celtic as Brendan Rogers side head to norway to take on rosenborg in the second leg of their Champions League qualifier. Hello and welcome to the bbc news at six. There is new hope tonight for thousands of families who live with the prospect of passing on inherited diseases to future generations. For the first time, scientists have successfully re pa i red a faulty gene in Human Embryos. The us and south korean team used a process known as gene editing to correct dna that causes a deadly Heart Condition. The Contraversial Technique is still at the Early Research stage, but it raises the hope of preventing 10,000 gene disorders, which pass down the generations. 0ur medical correspondent fergus walsh reports. The goal could not be more ambitious, to eradicate inherited diseases. These scientists have taken an impressive first step on a long road, editing dna in Human Embryos. So how is it done . Inside the nucleus of each of ourselves is oui gene the nucleus of each of ourselves is our gene known, brilliance of pieces of dna. It is the Instruction Manual for life. The scientists were targeting a faulty gene that causes a serious Heart Condition. They have fixed a faulty gene. They then injected the gene editing system, which scans the dna like a Spellchecker Awsat now. It then cuts both strands of the dna, and removes the faulty gene, a healthy copy of the faulty gene, a healthy copy of the gene from the egg is then naturally inserted. Here are some of the embryos from the study in the Journal Nature after being edited, 42 of 58 embryos were corrected. They were allowed to develop a five days, none was implanted. Were very excited about the work. The research has been welcomed by 18 in london, who have a license to edit Human Embryos. They say the technology could eventually help many families. There are some nasty genetic diseases like huntington, or a disease that affects Heart Function later in life, which can blight families for many generations. So a method of being able to avoid having affected children, passing on the defective gene, can be really very important for those families. Nicole mowbray has the same Heart Condition that was corrected in Human Embryos. She 110w was corrected in Human Embryos. She now has a defibrillator implanted in her chest, in case her heart stops. She has a 50 risk of passing on the condition, but is unsure of whether she would consider gene editing. Condition, but is unsure of whether she would consider gene editinglj wouldnt want to pass on something that caused my child to have a limited life or a painful life, or a life of risk. That does, obviously, come to the front of my mind when i think about having children. I wouldnt want to create the perfect child in inverted commas, i feel like my condition makes me me. Previous attempts at editing Human Embryos in china led to serious errors in the dna. There is a lot of work needed before this can be considered safe, and it raises ethical issues about how far science should go to create healthy babies. Big advances, as you suggest, but lets be clear, this is not something that will happen next year. We are at the foothills of this technology, there is still a mountain to climb. This is controversial, george, critics will say this is the road towards designer babies. Lets be clear, what we are talking about is designing out faulty genes that cause terrible inherited disorders, often fatal. Not designing in positive traits. Critics say that will come next. Couples at risk of passing on a genetic disease already have options, they can have Embryo Screening through ivf. But this will allow more healthy embryos to be selected for them. Lets be clear, we are selected for them. Lets be clear, we a re yea rs selected for them. Lets be clear, we are years away from potentially curing genetic disorders using gene editing, and still further from enhancing humans. Fergus, thank you. Four men from the West Midlands have been found guilty of plotting a Terrorist Attack similar to that carried out on the soldier lee rigby. A gang calling themselves the three musketeers, along with one other man, were planning to attack police and military targets here in the uk. For security reasons, some of the trial had to be held in secret, as phil mackie reports. A major alert near the centre of birmingham last august, homes and businesses were evacuated, the bomb Disposal Unit had to be called. It was the culmination of an elaborate operation resulting in several arrests, including these men that called themselves the three musketeers. Undercover officers found a cache of weapons in the back of one of their cars. There was a partially constructed pipe on, an imitation firearm, and a meat cleaver. They found them behind that read more, which was a small delivery business, but it was all a front. The boss was an Undercover Police officer, and it had been set up police officer, and it had been set up by police officer, and it had been set up by m15 as part of an elaborate deception to catch the terror cell they thought was plotting to attack either ili . We all police, and they recruited two members to be delivery drivers. Naweed ali and Khobaib Hussain were previouslyjailed. In prison, they met mohibur rahman, who served time for terrorist material. They left prison with the same itch to missed ideology. Then a friend was also recruited. When they held meetings in birmingham and stoke, they were being watched. They believed that violence was the a nswer believed that violence was the answer and they were prepared to use violence somewhere in the United Kingdom in the furtherance of their ideology. Four very dangerous individuals, who had they not been stopped, they would have caused loss of life somewhere. The Ministry Of Justice says it has supported training, but this Case Highlights the potential dangers from those with an extreme ideology when they are with an extreme ideology when they a re let with an extreme ideology when they are let out of prison. The fact that people are being released, and you know they are terrorists, they have been convicted, they are released back into society and there is no reason to think they are no longer radical. We need to ask ourselves a question, are you happy with that . It is suspected the four men will be jailed tomorrow, three of them for a second time. New research on the governments state Pension Reforms has found that more than a million women in their early 60s have become poorer as a result. According to the Institute For Fiscal Studies they are losing, on average, more than £30 a week. Meanwhile, the government is saving more than £5 billion a year. Emma simpson has been looking at the plight of some of the women affected. No trips to the pictures. No trips to the pub. My life, my lifestyle, has changed. I cant do the things i used to do. Surely from aberdeen is 61. She cant work because of ill health, and she cant get State Pension eitherfor ill health, and she cant get State Pension either for another five yea rs. Pension either for another five years. The effect it has had on me, ending it all. Because having to. Rely on your family. Ending it all. Because having to. Rely on yourfamily. But ending it all. Because having to. Rely on your family. But my son said to me, he said, mum, you brought me up. You always gave me andi brought me up. You always gave me and i had it. Its my turn. But its still hard. The decades, the pension age has stayed the same, women retired at 60, men at 65. But by2020, women retired at 60, men at 65. But by 2020, both men and women will have to wait until they are 66 before they can draw their State Pension. The changes for women began in 2010, and it all depends on your date of birth. So, for instance, if i was born before the 6th of april 1950, i would still get my State Pension at 60. But if i was born two Yea Rs Pension at 60. But if i was born two years later, i would get that benefit at 62. And if i was born a couple of years after that, then i will be 66 before i draw my State Pension. This former Pensions Minister told me the government was right to take action on the spiralling pensions bill. But. Given the savings of many millions of pounds that the government is making, a small amount of that could be allocated to helping those women that have been pushed into poverty, bridge the gap between when they would have got their State Pension, and when they will now receive it. Women have been campaigning for that. Ministers insist the changes are fair, we are living longer, and women retiring now will get a State Pension longer than previous generations. They just pension longer than previous generations. Theyjust need to get there. It looks like the record for a Football Transfer Fee is about to be shattered again, with French Club Paris St germain preparing an astonishing £198 million bid for the brazilian footballer neymar. Thats more than twice the current record. Neymars current club, barcelona, Have Given Him permission to hold talks. One of his advisers says the deal could be done by the weekend. Our sports news correspondent Richard Conway is in paris. This is a huge amount of money, i suppose it is footballs version of hyperinflation, richard. It is a huge amount of money, but then, one of the mottos of this club is dream bigger. And there can be no bigger dream than signing a player of neymars calibre. This morning, he went to barcelona, his current club, to officially train. But they gave him permission to knock train, instead he said goodbye to his current team mates. Then the club issued a statement saying he had formally requested to leave, and that full release clause in his contract must be paid in full if he is to depart, that is 222 million euros. Today at the club shop on the champs elysees, a lot of fans and people excited, asking if he has signed yet. Not just people excited, asking if he has signed yet. Notjust yet. But the inevitability is it is going that way, and by the weekend, in times of paris Saint Germains first League Fixture of the season, we will see neymar in the blue shirt of paris saint germain. Neymar in the blue shirt of paris saintgermain. Richard, thank you. After 70 years of official public engagements, the Duke Of Edinburgh made his final solo appearance on royal duty today. Now 96, hes the longest serving consort in british history. 0ur royal correspondent Nicholas Witchell is at Buckingham Palace for us. He didnt let the rain stop him, did he . It certainly did rain on his final solo parade. We mustnt forget that we will still see him from time to time alongside the queen at major events. But for someone who is famously no nonsense in his approach, and he doesnt really do too much in the way of sentiment, i thought he looked really chuffed at his sendoff. It was the kind of Afternoon Weather Wise which might have made anyone glad to be retiring. Quite apart from the fact that in the dukes case hes been doing this sort of thing for 70 years. But there he was, on the forecourt of Buckingham Palace, a man of 96, standing to attention in the pouring rain for the salute he has heard so many times. There were many things to remind him of the past decade. The parade had been mounted by the Royal Marines, the fighting force which is part of his beloved royal navy. In which he served in world war ii. And in the background was the palace where he has attended so many events, Garden Parties and the formal dinners, alongside the queen. And where his programme, 22,000 solo engagements, more than 5000 speeches, has been planned. The duke strode across the forecourt, no stick for him and woe betide anyone who might suggest such a thing. And as he went, the crowd outside the palace applauded. By now, it was almost time to go. The Royal Marines gave him three cheers. The duke waved his hat and strode away. And as he went, the band of her majestys Royal Marines played, for hes a jolly good fellow. After 70 years service, and with his own separate programme of royal engagements now concluded, who today would have dared to disagree . Nicholas witchell, bbc news, Buckingham Palace. Our top story this evening scientists think theyve found a way to eradicate inherited Heart Disease by removing faulty genes. And still to come they were the stars of 2012, what happens when they pass the baton to a new generation . Coming up in sportsday on bbc news we have a visit from the world and olympic champion adam peaty who tells us The Best Is Yet To Come in his career as he prioritises in america, the Trump Presidency has been controversial for many reasons. Among green activists its his plans to allow more Oil Exploration in the arctic ocean that has ignited protest. A coalition of organisations has called the plan unconstitutional. The Inupiat Whale Hunters of Northern Alaska could feel the greatest impact of any future drilling. Our environment correspondent Claire Marshall travelled more than 300 miles north of the arctic circle, report from uchiarpic. The climate is changing and the ice that covers the arctic is disappearing. Here the conflict between the Natural World and the business of oil is at its most stark. This town is the furthest north in the united states, so remote it is cut off by road from the rest of the country. The inupiat call the ocean their garden. And this is where they store the harvest of whale meat. Is that kidney . If thats kidney put it on top of the heart. I dont know where the heart is. Its right in front of you. This is an Ice Cellar Dug Out of the permafrost, the perfect freezer. It helps to sustain them during the long arctic winter. Back up. As your mouth starts to warm it up it softens up like chocolate. Its a richness you cant get from anything else. So take that one. Illjust have a little one. Put it on your tongue. Dont try and chew it real fast, just kind of let it dissolve a little bit in your mouth. Then start chewing it. But it should. Its not oily. Its not like crisco oil. No. No, its not my thing. I dont mind the meat, i dont mind the meat of it, but im not mad on that. Hunters always have a knife on them. We use white because the whales can see colour. Niaomi is a whale hunter. She takes us to a feast on the beach. The inupiat have hunted the Bowhead Whale in their sealskin boats for thousands of years. Now donald trump intends to reverse the ban on drilling in the arctic ocean. And many are afraid they will lose their way of life. I honestly want to be at the shore and tell him, no, you cant. I mean, just imagine if there were to be a big spill in the ocean. None of this would be happening right now. But like the rest of alaska, this town is almost entirely dependent on oil. Taxes on the industry in other parts of the country pay for the infrastructure and every alaskan gets a yearly cash dividend. Once you start slicing it all off. Fred brauer believes that oil is the only way they can carry on hunting. You cant go whaling for free. It costs money to go whaling. So theres an opportunity to coexist together. And an opportunity for not only industry to thrive but also the local traditional hunters. We are closer to the north pole here than we are to washington, dc. But the white house has its eyes firmly fixed on this region. It is an unstable world and what lies beneath this ice could be crucial to the Energy Security of the united states. But drilling here would be very risky, just as it is risky to hunt. Armed in case of polar bears, some other hunters take us out to the very top of america. The arctic is warming twice as fast as anywhere else on the planet. Most scientists agree that oil, a fossilfuel, is helping to bring about this change. I love my people and i love my land. Maybe we should start looking ahead for something thats more renewable. Maybe wind in the winter and solar in the summer. Any options are better. Traditional inupiat dancers tell the stories of their land and its creatures. Donald trump and his decisions may well be woven into the songs of the future. Claire marshall, bbc news. Studio an Emergency Rescue operation has taken place because of bad weather in Northern Ireland. The cadets, aged between 12 and 17, got into difficulties in the mourne mountains. Sixteen of the group, from england, were said to be suffering from hypothermia. The Ministry Of Defence has confirmed that all are now safe and accounted for. What happened up there . They were here for a Camping Exercise when they got into heavy wind and rain, treacherous conditions. At lunchtime, the Northern Ireland Ambulance Service declared a major incident, involving members of the mountain rescue teams, the coast guard, the ambulance themselves, the police, as well, throughout this afternoon, from the very Poor Visibility at the top of the mountain, out of the mist have been emerging four by four vehicles carrying teenagers, some of them on stretchers, some of them suffering from hypothermia and ankle and leg injuries but they are all now safe. The Ministry Of Defence has described this as a remarkable Rescue Operation and thanked all teams involved. A change in the rules on how much sleep in care workers must be paid could leave the whole system on the brink of disaster. Thats the message from the charity, mencap, which looks after people with serious learning disabilities. It says that demands from the Hm Revenue And Customs to backdate six years of payments to workers who provide overnight care could amount to a total bill of £400 million. The game of thrones star, Kit Harrington, has been raising awareness about the issue and hes been speaking to our health editor, hugh pym. Do they go together in groups to do their activities . With time out from his filming commitments, Kit Harrington is campaigning for a cause close to his heart. Hes concerned about a financial threat to charities which runs supported homes like this for residents learning disabilities. Kit harington. What is her favourite song . He is worried about the future Ca Re Of Song . He is worried about the future care of his cousin, who has Down Syndrome and learning disabilities. He needs to live the life that he loves living. My aunt cannot care for him in the way that she has, we need to find that for him, my worry is that we will not be able to. Care workers who stay overnight used to get a flat rate of around £30, including when they were asleep but after a court ruling, employers now have to pay the minimum wage for every hour, around £60 a night, they have been told to fund six years of back pay, which they say is unaffordable. What is favourite colour . Ahmed is a care worker with mencap, he does several sleep in shifts each week. He says getting what he is owed from previous years is important. Mencap. He knows that charities. To find the money. Sense of a reward, an incentive am a it would bust my morale, and my motivation, to do what we do right now, even more. Unions sake it is only what the care workers deserve. They need to be paid, they have done this work already. Unions say. Because of the important work that ca re because of the important work that care workers do, they deserve to be paid this money. A Whitehall Spokesperson has said kit believes the government has to find the money. Charities can pay this bill, if they cannot pay this bill, then people like the guys that are here, who we are here with today, will be left without the care they need, that just today, will be left without the care they need, thatjust cannot happen. It needs to be. It needs to be footed by the government. Is echoing the fears of Charity Care Providers that being forced to find the money will lead to closures with vulnerable residents the big losers. Studio for years these familiar faces have dominated British Athletics for years but as the teams begin arriving in london for the World Championships, lets have a look at who will pick up the baton, once they are gone. Heres Natalie Pirks gold for Great Britain again. Expectation rather than hope, so successful have british athletes been over the last few years that older moments have become the norm, but guaranteed medals are a thing of the past. Yes again is hill has retired, World Champion long jumper Greg Rutherford is out injured, mo farah is bidding farewell to the track. Jessica ennishill. I have achieved what i wanted to achieve, and it would be nice to be able to finish on a high. I guess, why not do it where it all started, in london, at that track. Where i became 0lympic london, at that track. Where i became olympic champion, that is what changed me as an athlete. You come back years later as the World Champion, i decided i am going to end it at that track. Aggressive running from laura muir. Who are those moving into the spotlight . Laura muir is aiming to do the middle distance double in both the 1500 and 5000 metres despite fracturing her foot in june. Look at the great she is showing. Currently studying to become a vet, the 24 year old juggles her love of animals with a tough training programme. She said five british records in the last 12 months, but she wants much more. Making those british record, i am very happy to have done that, i am sure down the line there will be somebody coming up line there will be somebody coming up and breaking my record. They are things that stay with you for ever. Uk sport has targeted six to eight of those medals, a big ask for a squad juggling injuries, the Bigger Picture focuses on the next generation. Bornjust a picture focuses on the next generation. Born just a few miles from the london 0lympic site, never know Mitchell Blake is the second fastest 200 metre runner of all time. Nethaneel mitchell bla ke. The 23 year old believes now it is time for new athletes to write their own chapter in british sporting history. People are seeing a changing of the guard, Jessica Ennis hill, mo farah, what they have done is remarkable, there are feats cannot be replicated, they have made their own legend am a wee want to come here and build our own legacy. It is always hard to say goodbye but fond farewells bring new beginnings, Podium Places may not be as plentiful in these championships but the potential for Future 0lympics will shine through. Studio talking about the rain over Buckingham Palace, iwonder whether it is going to last. We will start with a glimmer of hope, there were some decent weather across northern scotland, blue sky all day, Cloud Building over the last few hours. For most of us, more like this, central london, mid afternoon, wet and quite windy as well, low pressure in the atlantic, driving the Weather Fronts across the uk, thatis the Weather Fronts across the uk, that is what has brought all of the rain. It is on the move, moving north, and east, so it will get up into northern wet and windy. Eventually, that gets out into the north sea, only to be followed by a whole rash of showers coming in from the west, pretty wet by the end of the west, pretty wet by the end of the night, across the western side of the uk, drierfurther east, temperatures holding up, 15, 16 degrees, 12 and 13 in the north. U nsettled degrees, 12 and 13 in the north. Unsettled through tomorrow, centre ofan area unsettled through tomorrow, centre of an area of low pressure is drifting, light winds, heavy, thundery showers, hail, a lot of Rain Ina Thundery showers, hail, a lot of rain in a short space of time. Further south, showers moving through quite quickly on the breeze, dry and bright interludes. Top temperature 21, 20 two. Tempered by the breeze. And in the other teams across the breeze. And in the other teams a cross m ost the breeze. And in the other teams across most of scotland, 18, 19 degrees. The low that is driving the weather is drifting toward southern scandinavia, as we get on, it will still be under its influence. Not as breezy as it will be tomorrow. Still some showers around, not as frequent or as heavy, affecting many northern and western parts, a few drifting further east as well. Light wind, should feel pleasant enough. Still some showers around, saturday, best of the weather in the south west. Not such a bad day on sunday but rain coming in from the west. Thank you very much. A reminder of the main story scientists think they are a step closer to preventing inherited diseases being passed on in families. That is all from the bbc news at six, it is goodbye from me, on bbc one we will nowjoin the bbc news teams where you are. Hello. This is bbc news. The headlines. For the first time scientists have successfully repaired a faulty gene in Human Embryos. The us and south korean team used gene editing to correct dna that causes a deadly Heart Condition. Four men from the West Midlands have been

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