Round the world challenge. Holding off a late challenge from britains alex thomson. Good afternoon and welcome to the bbc news at one. Theresa may has outlined her vision of a truly Global Britain during an address to Business Leaders at the World Economic forum in davos. The Prime Minister said the uk was facing a period of momentous change and must forge a new role in the world. She said the road ahead would be uncertain at times but britain sought to become even more global and internationalist. And mrs may had a warning for bosses whose companies have a global reach, telling them not to forget their responsibilities to communities. Our Business Editor simon jack sent this report. Voiceover theresa may stepped out to face the global elite she has been so scathing about. And audience she acknowledged was still struggling to understand the referendum result. I know that this, and the other reasons britain took such a decision is not always well understood internationally. Particularly among our friends and allies in europe. Some of our European Partners feel that we have turned our back on them, and i know that many fear what our decision means for the future of the us itself. But she reassured them it was about taking back control rather than turning our back and said the uk remained a faithful partner. For the future of the eu itself. Britain will always be open for business and open to investment in infrastructure, open to businesses, open to those who want to buy our goods and services, and open to businesses. Breaking straight afterwards, the dutch Prime Minister insisted there would be a cost for leaving. The uk is making a choice, to control migration, and they are paying a huge price, the economic welfare of the uk will be impacted negatively, they will be leaving the biggest market in the world. After hsbc and ubs announced jobs will be leaving the uk, better news today from barclays. I think the uk will continue to be the financial lungs for europe. We may have to move certain activities and we may have to change the legal structure that we use to operate in europe but it will be at the margin and will be manageable. She saved her sternest language for business. At the same time as promoting this openness, we must heed the underlying feeling that there are some companies, particularly those with a global reach, who are playing by a different set of rules to ordinary working people. And so it is essential for business to demonstrate leadership. Did the audience get the message . Business leaders i speak to really do understand that not everybody gets the benefit of globalisation in a practical sense or an understandable sense, but i sense a real determination to fix that. She made it clear that the government will intervene to improve behaviour if necessary , intervene to improve behaviour if necessary, a hint, perhaps, of what we get from her industrial strategy unveiled next week. Studio and we speak to simon now. How did the Speech Go Down pretty tough crowd, globalisation, free trade, it is like a religion, people make a programme each year, they Ta Ke Make A Programme each year, they take it as read that Globalisation Isa take it as read that globalisation is a good thing. Donald trump thinks it is not such a good thing and they brexit result have made people question whether there is public support for that. Where is theresa may going to come out . She has said that she is in favour of globalisation and free trade but if we dont take everyone with us, we will lose the public consent that we need if we are going to preserve the current system. The message was clear, iam behind current system. The message was clear, i am behind free trade and globalisation but clean up your act and if you dont, i am happy to intervene. She has industrial strategy she is unveiling on monday of next week. This was a flavour, a message back home, we are going to get stuck in and make sure that economic success and growth reaches all parts of the country and society, that was a big message today. Thank you. Our assistant Political Editor norman smith is in westminster how worried are the government about Business Reaction . They have to be acutely worried because we have already seen two big banks, hsbc and ubs, signalling their poise to relocate thousands of jobs. They are poised. The boss of toyota equally signalled disquiet about how his company, which implies 3000 people in britain, is going to remain competitive post brexit. For all theresa mays continued criticism of the so called international league, the very people in her audience, international league, the very people in heraudience, she needs those people on board to make a success of brexit and make sure britains continued economic prosperity, because like it or not they have in their Hands Thousands Ofjobs in britain, they bring in billions of pounds of investment, and are absolutely central to our economy. It was significant, i think, that theresa may did not repeat her warning earlier in the week that if we do not get a deal we will walk away and have to rely upon World Trade Organisation rules, raising the terrifying prospect for many of tariffs. She has the hope that business will give her time as well to flesh in some of the detail on Critical Issues around immigration and trade, and that is a rather big difficulty. During this two year period of negotiation, there is almost certain to be uncertainty, the one thing that business hates above all. At least 30 people are missing after an avalanche struck a hotel in a Mountain Resort in the central Italian Region of abruzzo. The avalanche happened after a series of powerful earthquakes hit the area yestereday. The first to help arrived on skis because all the roads were blocked. The mountainous region of Central Italy was hit by a succession of four earthquakes on wednesday and further tremors were reported overnight. Bad weather from further tremors were reported overnight. Bad weatherfrom recent storms has brought down power lines and cut off villages. Rescue operations are under way in other parts of the region as well. Our correspondent Frankie Mccamley repaorts. Voiceover buried in snow, barely visible, this is the three storey hotel hit by last nights avalanche. Barely recognisable to what it looked like before. Inside, the extent of the damage is becoming clear. What looks like a Reception Leading to corridors now unrecognisable, full of snow and debris. Up to 20 people were staying in the Hotel Rigopiano along with Seven Members of staff, but faced with bad weather it took rescuers hours to get here. Translation the hotel was reached at 4 30am by courageous men, who faced unbearable situations. They reached a place and saved two people. They are now working to bring the means of transport that are difficult to bring. On skis, in the early hours of this morning, Mountain Rescue teams faced snowstorms to get to the area hit. With routes blocked to emergency vehicles, only manpower could save those trapped. One man is led to safety. Nearby, relatives faced an agonising wait for news. Translation they are extracting them from the hotel and bringing them to hospitals, i think, but i dont know, because it is impossible for us to go up. Others text loved ones inside, urging them to stay calm. This morning, roads to the site are slowly carved out, reopening the area, which is popular with skiers. Conditions in a region thats already fragile after being hit by a series of earthquakes, has begun to ease. Conditions have begun to ease the those that have reached the hotel but doesnt including children are still missing as the extent of this tragedy begins to unfold. Studio a thousand british holidaymakers have arrived back in the uk from the gambia amid concerns of a worsening political crisis. The Foreign Office is continuing to advise people to avoid all but Essential Travel to the country, after its outgoing president refused to meet a midnight deadline to hand over power. Thousands more tourists are due to be brought home in the coming days. Our correspondent jonny dymond reports. Voiceover nigerian troops prepare for the worst. They are moving into position in gambias neighbour, senegal. The plan, to intervene with force if gambias president doesnt leave office. Power is meant to be handed over in gambia today, but the four term president yahya jammeh wont let go. In manchester, evacuated british tourists spoke of tense times in the west african state. Last night it got a bit serious. All the restaurants shut down, all the shops shut down. It got really scary. And then this morning, because we had heard that 15 planes had come out to get the dutch people, and we were like, what about the english . , you know. Where the ferry was, everyone was getting on the ferry, all the gambian people, carrying all their possessions, suitcases on their heads and everything. It was a real struggle to get on the ferry. Everybody was just fleeing. In the gambian capital, the president of mauritania flew in. The regions leaders have called for president jammeh to stand down, and peacefully hand over power. He insists he will go on. In neighbouring senegal, the winner of the election is in talks to, he says he will take power today, in a ceremony at the gambian embassy, in senegals capital, dakar. One country with two president s, one of them has to blink or bloodshed looks unavoidable. Studio new figures from the office for National Statistics show that there were 11. 8 million incidents of crime in england and wales in the last year. Its the first full year when the offences have been included in the crime survey. Overall police recorded 8 percent more offences year on year. With just one day left until donald trump is sworn in as the 45th president of the united states, preparations are in full swing in washington but can he deliver the jobs and trade that hes promised . This week, weve been taking a road trip through the heart of america on route a5. Today our correspondent jon kay is in tupeloh low in the state of mississippi the birthplace of Elvis Presley. Today our correspondent jon kay is in tupelo in the state of mississippi, the birthplace of Elvis Presley. Jons been speaking to the people there about their hopes for the next four years. Marching band plays. Voiceover one last practice before heading to washington. Tonight, the Tupelo High School band will be travelling 900 miles, from mississippi to the capital, to play at president trumps inauguration. Your face is going to ache. Yeah, i think so what are you most excited about . Just marching in the parade in getting to see washington for the first time. What do you think of your new president , trump . Erm. Donald trump got 60 of the votes in the state. The students might be playing for him, but that doesnt mean theyre all fans of the new man in the white house. And down if you had been able to vote, put your hands up if you would have voted for donald trump . Not exactly overwhelming. Three. I think some of his ideas are pretty great, and i think he actually can make America Great again, wejust have to believe in him and see what happens. You didnt put your hand up . No. Why not . I dont like him. Youre about to go and play for him . But, like, im forced to. I like washington, i dont like him. Youre going for the trip, yeah . Basically. Lots of celebrity said no, didnt they, to performing at the inauguration. Why did you say yes . Im not really a fan of trump, but im going for the experience and forthe band, im not going for him, im going for me. Music matters in this small, southern town. In fact, it put tupelo on the map. Just off route 45 is the tiny house where Elvis Presley was born. But were not here to talk about the king, we want to talk about the new president. Because as well as producing rock n roll stars, tupelo produces cars. Look at this 1957 chevrolet. I wish wed had one of these for our road trip. Donald trump has promised a return to the heyday of american manufacturing. He says hell create jobs and improve trade deals. This local Steel Company supplies the car industry. They believe the new president will cut red tape, cut taxes and boost growth. I feel very optimistic. The boss here hopes donald trump can fill his government with top business people. And in the end, if they dont do it, hell fire them but its not the apprentice, is it . Its more complicated, its more nuanced. Is he going to be able to cope with the political, diplomatic challenges . That remains to be seen. I think he is introducing something into the Political Landscape thats never been done before. Anything that you take to the parade is subject to being searched. The students are ready to go. Tomorrow, they will perform outside the white house, and this nation will have to march to a very different beat. Studio well tomorrow on the final day of his road trip following route a5, jon will be deep in donald trump terriitory in mobile in the state of alabama, at the uss alabama, a World War Two battleship which is now a museum. And you can watch full coverage of the Inauguration Ceremony live from washington tomorrow here on bbc one with coverage starting at four oclock in the afternoon. Our top story this lunchtime. Theresa may warns that britain is facing a period of momentous change after brexit and needs to forge a new role in the world. And coming up over and out for novak, as he loses to an outsider from uzbekistan ranked 117 in the world. Coming up in sport at 1 30pm despite a strong start, englands bowlers fail to control indias batsmen as yuvraj singh and ms dhoni both make centuries in the Second One Day International in pune. In the next few hours one of the toughest yacht races in the world is coming to an end with frenchman Armel Le Cleach expected to cross the finishing line first in the vendee globe race. Itll mean second place for british sailor alex thomson, who had turned round a disastrous start and broken two World Records to come so close to victory. Our Sports CorrespondentNatalie Pirks is at the finish line at Les Sables Dolonne on Frances Atlantic coast. Hes battled everything the ocean has thrown at him, eating only freeze dried noodles and jelly, and survived on as little as 20 minutes sleep every few hours. Its a fair bet Alex Thomsons last few weeks have been very different to yours. When he set off with 28 other boats on the 6th of november, the Hampshire Yachtsman waved goodbye to his wife and two Young Children and attempted for the fourth time to become the first briton to win the vendee globe in the races 27 year history. We await the arrival. In fact, the only briton to win any kind of solo nonstop round the world race was thomsons mentor, sir robin knox johnston, in 1969. When thomson arrives back here at Les Sables Dolonne in the early hours of tomorrow morning, hell have racked up between 25,000 and 30,000 nautical miles, been past point nemo, the furthest point from civilisation on earth, and battled 23 foot waves. Hes making it look easy but its far from it. Probably the most difficult Sporting Challenge left on the planet today. When people ask for a photo we always say several thousand people have now climbed Mount Everest and over 400 people have been into orbit, into outer space, but less than 100 people have managed to sail single handedly nonstop around the world. For alex there have been good moments. This is the Southern Ocean and its sunny. Bad moments. I do wonder why i do it, sometimes. And moments over christmas where his family worried he was going slightly mad. Jingle bells, alex sails. His team believe if it wasnt for hitting something and ripping one of his hydrofoil is clean offjust two weeks after the start, hed already be back, having bunn in record time. Hes gone to around 80 miles behind the leader, Armel Le Cleach. It helps that earlier this week he smashed the world record for the greatest distance sailed solo in 2a hours. A new record. His rival knows hes been hot on his tail. It seems hes been hot on his tail. It seems he will get his wish, a win from thompson now looks impossible, barring a major Technical Problem for Armel Le Cleach. But when thomson arrives back not only will his family be waiting for him, but his family be waiting for him, but his team also have promised to have one hand the two thinks he has craved during his epic voyage, a hot burger and a cold beer. Natalie pirks, bbc news, bundy. Vendee. Conservative controlled Surrey Council is to hold a referendum on whether to increase council tax by 1596 whether to increase council tax by 15 to fund improved social care in the county. The council says it has a huge gap in its budget as a result of cuts from westminster. The area includes the constituencies of the chancellor and the health secretary. A new initiative has been announced to fight three deadly diseases scientists believe could spark the next global epidemic. It aims to develop vaccines quickly for mers, lassa fever and the nipah virus. Our Global Health correspondent Tulip Mazumdar has more. What will hit us next in the great Global Lottery of Disease Outbreaks . Maybe a virus we already know about, or perhaps a totally new one. The Ebola Outbreak in west africa exposed how utterly unprepared the world is for new epidemics. More than 11,000 people died, partly because there were no vaccines to protect them. The Research Charity the Wellcome Trust is part of a new coalition which is concerned that the next outbreak could be even deadlier, especially if its an airborne virus. Weve got lucky so far, but the world has major gaps for infections we know about which could cause ebola like events, but then spread around the world very quickly, and that puts the world in a very, very vulnerable place. Scientists have identified three obscure viruses they want to fast track vaccines for. Nipah virus spread to humans from fruit bats. The disease can cause swelling of the brain. Outbreaks have mainly occurred in bangladesh. Lassa fever is common in west africa. It kills around 5000 people every year. The last one is mers middle east respiratory syndrome. It is believed to be spread by camels. Its killed more than 650 people, mostly here in saudi arabia. This lab in oxford is one of the Research Facilities trying to come up with a vaccine to protect people against mers. Its one of the most advanced vaccines out there. This is the clinical Bio Manufacturing facility and this is the basis for the mers vaccine. Now, it will be scaled up over the coming months, and its expected that hundreds of vials of this will be ready for human trials by the end of the year. If this vaccine does work, it could still take a decade or so to get it to those who need it. Historically money for these obscure viruses hasnt been forthcoming, and the regulatory process is long and complex. This sort of Research Takes years and costs hundreds of millions of dollars. These labs also worked on the ebola vaccine. We got safety data in oxford, yet those vaccines were not being used in west africa where the Ebola Outbreak was happening and people were dying of the disease while we were testing the vaccines. We dont want to be in that situation again. This sort of Research Takes years and costs hundreds of millions of dollars. It may not be any of these three viruses that cause the next epidemic, but if it is, putting time and money and now could stop small outbreaks becoming the next Global Health emergency. Tulip mazumdar, bbc news. Tv commercials you either love them or hate them but which ads were the most complained about last year . Well, the Advertising Regulator says moneysupermarkets Tv Commercials got the most, with almost 2500 complaints about the series of ads which Feature Dancing Builders and businessmen in hot pants and stilettos. Our Media CorrespondentDavid Sillito reports. Its been all over the outbreaks, the man in the suit with the hot pa nts the man in the suit with the hot pants and high heels. In the list of most complained about adverts the various different dancing commercials appear not once, not twice, but three times. Moneysupermarket, 2500 complaints. What were the problems people had with it . They had three places in our top ten and the complaints were all about provocative dance moves. Some people perceived the move is to be too overtly sexual for the time of day it was shown. And crucially for us, the test is does it cause serious and widespread offence. We thought in this case some people might think is in bad taste, other people might think its fun, but we thought it didnt cross the boundary into serious and widespread offence, so we didnt uphold those complaints. So lots of complaints but no ban. It was the same for this, in which blind footballers mistake a ball with a bell for a cats jangling collar. It mistake a ball with a bell for a catsjangling collar. It topped mistake a ball with a bell for a cats jangling collar. It topped the complaints list in 2010. Six years later the complaints are still pouring in. We came to the conclusion its fine firstly because the english Blind Football Team were actually very complimentary about how we presented blind people. But they were not unhappy, but what about the cat . Crucially on the cat, the advert was shown after kids programmes had finished and very few kids would be watching it so we came to the conclusion its the right side of the line and happily the cat is shown alive and well. Both then our choices about the boundary of offence but some con plaint about adverts that were not on the list, the hard fought Referendum Adverts that were not on the list, the hard fought Referendum CampaignDrew Angerfrom the hard fought Referendum Campaign drew anger from both sides but the Advertising Standards Authority doesnt do politics. David sillito, bbc news. Britains Courgette Crisis continues. The on trend vegetable is still missing from many Supermarket Shelves, with consumers taking to social media to show their outrage. Many are blaming the rise of courgetti for the shortage, but suppliers say its down to the cold winter. Well, as our correspondent Judith Moritz reports, the courgette is not the only vegetable in short supply. The common courgette isnt normally thought of as a delicacy, but the vegetable is in such short supply its fast becoming a luxury item. Prices are double what they were a year ago and these Vegetable Wholesaler that londons new Covent Garden market are feeling the effects. Some of the green stuff has really been affected and things we wa nt to really been affected and things we want to bring in are just too expensive. Normally courgette far six or seven pounds, they are now £22. Ive been in this trade for 40 odd years and ive never known anything as bad as this, where everything is so dear. This is the reason why. Sunny spain is currently snowy spain. The south east of the country usually supplies 80 of europes Fresh Produce in winter mods but neither was a spare cha Ra Cterless Mods But Neither was a spare Characterless Snowman many crops have been hit hard by the big freeze. There was a spare carrot for this snowman. Many shops are out of cou rg ettes for this snowman. Many shops are out of courgettes and theres the inevitable social media hashtag. Its not just Supermarket Shelves that are running low. Online shoppers are struggling. Websites for sainsburys, morrisons and tescos were all Showing Courgettes as unavailable this morning. Leeds market this morning you could get cou rg ettes, market this morning you could get courgettes, but at a price. Our core customers coming for a bargain, because things are cheap and good. Cou rg ettes, because things are cheap and good. Courgettes, broccoli, cauliflower as and a few other things have gone the roots. We shouldnt get panicky, itsjust a courgette. Not all shops are reporting shortages. Supermarkets say they are working to improve supplies and it shouldnt be long before the Courgette Crisis is over. Theres been a big upset in the world of tennis today. The defending champion Novak Djokovic has been knocked out of the australian open. Djokovic a six time winner of the tournament, whos ranked number two in the world lost in five sets in melbourne to denis istomin, a Wild Card Entry from uzbekistan. Our Sports Correspondent joe wilson reports. Denis istomin, 12 years into his career, four and a half hours into the match of his life. The world number 117 from uzbekistan wasnt simply trying to stay with Novak Djokovic he was trying to break him, to find something more than hed ever located before. Listen. Denis istomin shouts. Commentator there it is. Inspirational. Jealousy, suggested shakespeare, is the green eyed monster. Istomins spectacles reflects his poor eyesight, not just decoration. Fifth set, 6 4. Commentator hes done it. To begrudge him this moment of glory would be desperately unfair, and Novak Djokovic, six times winner of the australian open, has learned in recent times to deal with defeat. Hes had to. There was not much i could do. Of course i was not pleased with my performance overall, but, you know, i have to congratulate my opponent today. Well, djokovics departure should benefit andy murray more than anyone else, considering murray only tends to lose to him in melbourne. Jamie murrays already out in the doubles. Kyle edmund lost and so did heather watson, defeated by little known american nearest the camera, jennifer brady. 10 8 in the third set and watson had five match points. But in dark blue here, britainsjohanna konta beat talented naomi osaka in straight sets. Save the shocks for another court. This one was kontas. Joe wilson, bbc news. Time for a look at the weather. Heres ben rich. This is southern spain. Wintry weather has been causing problems in the mediterranean. This picture from the mediterranean. This picture from the South East Spain is an example of the scenes we have been seeing. Winter really has taken hold across many parts of continental europe. These are the Afternoon Highs this afternoon across many central and eastern areas temperatures will not get above freezing. As areas of low pressure m ove get above freezing. As areas of low pressure move into the cold air across south eastern spain and also as we saw earlier on italy, we have seen some significant snowfall