The popular community drive had to be cancelled last year due to the coronavirus pandemic.
Beach cleans at 21 locations have been organised over the May 22/23 weekend, for what will be the 31st beach clean organised by Litter Free Coast and Sea.
On the Saturday beach cleans at Shell Bay, Studland; Knoll Beach, Studland; Middle Beach, South Beach and Old Harry Rocks, Studland; Southbourne Beach; North Beach, Swanage, and Boscombe Pier will be taking place.
Then on the Sunday litter-picks will take place at Sandbanks, Highcliffe Beach, Lulworth Cove and Durdle Door, among others.
Litter Free Coast and Sea is running the event in partnership with Clean Jurassic Coast.