1. Rate-control, along with anticoagulation, should be the main approach to managing patients with atrial fibrillation. 2. Compared to rhythm-control, rate-control resulted in a lower incidence of adverse events and no significant difference in mortality. Original Date of Publication: December 5, 2002 Study Rundown: Originally published in 2002, the Atrial Fibrillation Follow-up Investigation of Rhythm Management