Talaga says four of the cases have been reopened but racism, indifference and more Indigenous deaths have First Nations youth there on edge.
"Sadly, things are progressing but not at all fast enough," said Talaga, who co-directed the film with Michelle Derosier.
"Our children are still dying in the water, our people are still dying on the streets. It is something that we are still living with."
The film debuts online Thursday at the Hot Docs Canadian International Documentary Festival. "Spirit to Soar" centres on the deaths of Jethro Anderson, Reggie Bushie, Robyn Harper, Kyle Morrisseau, Paul Panacheese, Curran Strang and Jordan Wabasse.