Their Reuse Revolution campaign aims to raise money for the charity and help the environment.
The charity says nearly three in 10 people in the South West lose their lives to heart and circulatory diseases and every item bought in BHF shops goes towards funding research that could save lives.
BHF retail director Allison Swaine-Hughes said: “I want to encourage the local community to help start a Reuse Revolution by shopping preloved with us.
"Whether that’s by exploring our ranges online or paying your local BHF shop a visit.
"Not only will you save money and help the environment, but you’ll also help us raise vital funds for heart research that could save lives.”