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LONDON and NEW YORK and SINGAPORE, June 29, 2022 /PRNewswire/ --Sequential Skin Ltd, a leading skin genomics start-up, has been awarded an Innovate UK SMART Grant to fund a project on advancing current understanding of the skin microbiome in healthy and diseased skin - using their novel testing kits. Atopic dermatitis (AD) is a multifactorial chronic and recurrent inflammatory skin disease, affecting 20% of children and 10% of adults. Roughly 29% are moderate to severe cases, with healthcare and socio-economic costs of Pound 723M per year. This US $500k (equivalent to Pound 400k) project will be funded over 18 months to further the understanding of genetic and skin microbiome inputs, during disease progression, that may lead to helping to identify and stratify patients in the future. "We see a future where patients with recurrent and debilitating skin conditions are diagnosed in a highly precise way, at the point of care, which can then be followed by effective and targeted treatment", said Oliver Worsley, CEO, and co-founder. Highly disruptive to skin health Sequential willworkalongside dermatologistsinthe NHS to recruit patients and benefit from clinicians experienced in AD. "As a dermatologist, Sequential's technology will be highly disruptive in changing the way AD patients could be diagnosed and better treated in the future. I'm proud to be involved with the Sequential team in this project," added Dr Natalya Fox, a Dermatology Registrar at St George's Hospital. Sequential has already commercialised its skin microbiome testing kit for the personal care industry. Validated with over 30 personal care, pharmaceutical, or skincare companies to help evaluate how formulations affect the health of the skin-this has led to a vast database of biological data from the skin. Their technology has been further confirmed, having recently been listed as a finalist at the C&T All Awards, as the best testing method or tool. "Being backed by Innovate UK, not only extends our research further into understanding skin conditions like AD - but validates our next generation testing platform and the data we've compiled so far", added Albert Dashi, CSO, and co-founder. About Sequential Skin Sequential was the first company in the world to offer a consumer microbiome test, opening up the possibility of personalisation and improving skin health (Tatler article). Since then, they have made significant progress in using their novel skin microbiome testing kit for the use of evaluating personal care products, allowing for next generation sequencing in vivo (C&T article). Sequential products are the result of the team's combined 30 year+ of expertise in genetics, epigenetics, and microbiome research, backed by some of the world's most prominent venture capital companies such as Metaplanet, Scrum Ventures, SOSV, Genedant, and Ben Holmes (ex. IndexVentures). Testing B2B platform: www.sequential.bio Consumer product: www.sequentialskin.com About Innovate UK Innovate UK is the UK's national innovation agency. They support business-led innovation in all sectors, technologies and UK regions. They help businesses grow through the development and commercialisation of new products, processes, and services, supported by an outstanding innovation ecosystem that is agile, inclusive, and easy to navigate. https://www.ukri.org/councils/innovate-uk/ https://www.gov.uk/government/organisations/innovate-uk Contact: press@sequentialskin.com, +44 (0)7832 237937 SOURCE Sequential Skin Ltd

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