Mane was afforded his eighth appearance in the Champions League this season and utilized the opportunity to add to his tally.
RB Leipzig dominated the first half of the game but failed to get the ball into the back of the net, missing a few chances which they paid for in the second half.
After the restart, Liverpool seemed to awake from their slumber as they pressed aggressively for the opener.
Their efforts paid off when Salah broke the deadlock in the 70th minute after receiving a timely assist from Diogo Jota.
The Egypt international, thus, took his goal tally to 25 this season, scoring the most across all competitions among the Premier League stars.