According to Mayo clinic, a popular medical website, depression may occur only one time during the life time of a man where he is bound to experience multiple episodes of symptoms. The symptoms cut across feelings of sadness, tearfulness, emptiness or hopelessness, angry outbursts, irritability or frustration, even over small matters, loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports and sleep disturbances, including insomnia or sleeping too much In addition to the foregoing, it stated that tiredness and lack of energy over small tasks can also be considered to be symptom.