Another E! host, Jason Kennedy, commented on the post, writing, "It was a pleasure brother ����."
"You are a legend Ryan! ����❤️" added
Fashion Police's Brad Goreski in a comment.
The network said in a statement that Seacrest has been an "instrumental" part of its Hollywood coverage over the past several years.
"E! has long enjoyed our relationship with Ryan over the years especially as co-host of E!'s signature red carpet series," the statement said. "He has been instrumental in giving viewers a front row seat to some of Hollywood's biggest nights. We are extremely appreciative of his many contributions and he will always be part of the E! family."