The Sabres selected Miller during the fifth round of the 1999 NHL Entry Draft. He appeared in a combined 15 games for Buffalo during the 2002-03 and 2003-04 seasons before becoming one of the key figures among a young core that transformed the franchise following the 2004 lockout.
Miller assumed No. 1 duties on teams that went to back-to-back Eastern Conference Finals in 2005-06 and 2006-07, a role he did not relinquish until he was traded to the St. Louis Blues on Feb. 28, 2014. In the intervening years, he became a leader on the Sabres, a decorated Olympian, and a dedicated member of the Western New York community.