A little bit involved in the recent thing. Im delighted this recent thing you know i generally like both you know ive delighted ive always had great faith i think is a fantastic communicator he can make waves you can. Reach parts of other others cant and hes demonstrated the election so im really pleased i think hes going phenomenal brain a great personality enormous energy weve got the right and i have the right job because he may have reached out to the electorate that other tory politicians didnt but Donna Cummings his senior Strategic Advisor has already been. Making announcements that seem to suggest he wants a radical reform of the Civil Service which is long been suspected of a pro remain bias and a suspected i think i think it was i havent talked to everybody i think its. Apparently we were always hearing that there were senior Civil Servant. That did not the despised the the largest vote in this country in this countrys history breaks it how can Dominic Cummings really reform an organization like the Civil Service what is to be very difficult as you know when you get into government lots of forces come at you and a lot of them suffocate you in the end so you there is going to thought a very hard and determined battle hes going to take them on Civil Service does need reform it has been i think that in terms of achieving breaks it. Proved you have that just you know talking to Civil Servants i think much more importantly i think its been completely frozen by the events rather than thinking of how can we prepare for the next phase and i think that is a really difficult position and in the commonwealth of course we brush with the u. K. Government we do with 53. 00 governments we also know how Civil Servants can sabotage it is just they can leak documents they go and they will amerie hence my remark that you know this is going to be a very. Difficult battle for dominic call cummins to fight it genuinely is in a different space to most of the businesses in that its very difficult to. Sack a Civil Servant its very difficult to move them out of the Civil Service is you we had douglas cause well one of Dominic Cummings is that close colleagues in that campaigning on the show who kind of said only coming it was it was a sort of genius i dont show the you know do you think hes up to the job i think hes a remarkable you know its very clear sighted a very clear vision of. The point of our government that it isnt just about having ideas its youve got to do the long strokes and its like a rowing race you do a lot of this very early on to get speed then its into this and this bit is not so easy for a lot. Of dominic coming well long strokes are going to be going to be needed after the 31st of january and what do you see as the significance of this date of the 31st of january because people can say that is the date from which britain will be subject to all Customs Union and Single Market regulations from brussels and. And we will have no power whatsoever. As regards the regulations we now must know violet well a deal as you know for trade is going to be discussed im always amused by hearing politicians saying that they can do things within this timeframe of that time frame if the result will it will be done within the timeframe of 10 months i dont think businesses will forgive politicians if they dont get home with this. Because its stifling employment and stifling countries stifling. Activity and im not just talk about the u. K. Im talking about many of the European Countries that will stifle german is. Trade activity which is huge the United Kingdom and its a no brainer i mean we export hall for what we import to be given and i want to know that statistic sorry to interrupt you. But if you just take that statistic you would have kind of thought lets get this thing done because its actually in our interest to have a very harmonious exit exam because were going to hopelessly wrong when he said that dr johnson had hitched his his his ride was it to donald trump over the trade deal and that is why britain must support the United States on iran given johnson is actually double down on his support for the nuclear g. C. Agreement i think koeppen labor of got it wrong quite a lawful Boris Johnson they dont really understand and theyve tried to portray him as another trumpy isnt hes actually a centrist. And i think. You know hes hes much more moderate than people think and that will probably be the tone of his coming to some extent but what you just said about european multinationals c. E. O. s perhaps and boards believing that weve got to get this done now because as you said e. U. British trade is such a huge component of their businesses and world trade. Then they have the pennies drop with them and theyre going to still fight it because european bureaucrats i think the president already looking ahead to this is a very good point very very good point pen it penny suddenly dropped the trade a business level but the european. Government brussels has been open sure its all the way through. And it will be interesting to see how much pressure the board by the leaders of the countries like macro merkel to quickly speed up what should be a very sensible trade if not know who knows whats going to happen and it could be no deal which would be pretty disastrous for both parties but even more disastrous for europe but that if they still threatening yes but those who really want you to look at they arent if you look at the German Economy which is not growing its going backwards its been very reliant upon the motor industry never once read says oh you cant use german both by the french but what is being demonstrated in the next in the last 6 months to 12 months the slowdown in almost recession the German Economy has been entirely due to the motor industry failing to summon up because if you see if you look at that alone how important the u. K. Is to that motor industry then there will be significant pressures and theyll be significant pressures from the childs need to make sure that she has strong trading relationships having been in business all my life the fact is the best type of people you can do business with are people who pay their bills on time. Where the contract to support by the rule of law will come where you have a free market economy now britain takes all those boxes so we are a market that is incredibly desirable for all these countries well you say that the European Commission is trying to sue the u. K. At the mood for billions of pounds for alleged fraud between 2030 to 2016 i dont know whether these legal cases you see is another delaying tactic and if as you say Angela Merkel is pulling the strings then why would a slow wonderland be saying the deadline as it stands makes will break that impulse. Breaks a deal impossible already these procrastination. Is all on their own on their own head be it in my view ok better pull their finger out and get on with it well as you know they can threaten britain by a whole variety of ways what about the 3rd country deals with the european. Through 3rd party deals all existing with the European Union and the renewal of those in the rule over of those for britain apparently japan is saying Japanese Companies will rule it we locate of course Motor Companies if there isnt no deal breaks it but that country treaties with the e. U. Will not be permanently rolled over with the brakes well i find these things rather a paradox. In that japan supposedly makes these noises about. You know withdrawing the car industry and im not surprised theyve shot a plant in swindon because the cars are not really a desirable car in the way they used to be in the old days but then they go home or they then go and invest obama property and things like that but i dont see any signs of japan not being interested in doing a deal with u. K. Well that will be a job for the trade own voice because honda would probably disagree with you there but that is that of course like were. Telling you what must. Live on to live she says the the price of a new deal breaks it is a distant partnership with the e. U. Is it a clean break bricks or killing machine fluffing theres more of this why Boris Johnson is such captivating. Prime minister and leader is because hes positive. Come out and say we come to this and cant do that he comes out saying lets get this done lets get that done and by and large he has done everyone said no you cant redo the deal with trees a may go up he went did it there was a border in the eye. Oh but its a very conscious of all ifs and buts the rule but its a far better deal than the trees made and the deal that was acceptable to the members of parliament and he had less of a majority in theory than she did a good politician is someone who says lets do this lets try and do this lets lets see whats possible that ive always said that why Boris Johnson would be leader of this countrys gives hope you expect trade always now to be going around the commonwealth which you have a specific interest in and all these countries to rapidly start creating new frameworks of the british businesses can work with businesses in the developing world and the point about trade and im sorry fun of telling my grandmother how to suck eggs but about trade is that its activity. With trade you dont necessarily have to have a trade deal weve never had a trade deal with the United States our biggest single trading partner and our biggest relationship weve never had a trade deal with them you really need a trade deal where the north bank rules of engagement between parties are not certain will there arent similar rules of law about. Where the relation can ship can take you and you need happens in developing which happens definitely developing countries and you need to have a very clear picture of it what i see needs to happen in a new Global Britain is for us to embed all selves in markets where there is big population growth we talked about nigeria which could have a bigger population than the United States by 2030 we look at indonesia which is already north of 200000000 a vietnam a very. Fast growing population nearly 100000000 will be 120000000 i think 520252038 philippines a similar burgeoning economy and thats where we have to learn all over again. Where we have to start selling product now if in order to support that activity we need a trade deal to give a certainty and in the relationship then of course we need to have that they wont be done overnight because theyre not sort of necessarily off the shelf things you know what is a mad chicken in one place is not the same chicken another you know we have things we dont want to take they have things that they dont take from us but so theyre not as straightforward as the last but those are the there is there is a basic framework and we countries like russia i mean there was a countries of britain sanctions and you britain sanctions china as well you know trade that there will be trade agreements frameworks i cant see that as being top of the list can you i dont. Know who i but you know i think that. Clearly relationships with russia is a important thing for the future but im talking more about britain getting out much more in the on the global footprint in these a populations in the fall bigger than the European Union. The great potential. Thank you thank you after the break were down british physicist reza poll davis exposes the symbiosis of cancer in everyday life and how modern approaches a killing progress in Cancer Treatment told us of all going overboard to going underground. On this edition of crossfire we conduct a postmortem of the recent us around conflict what has changed in what bodes for the future issues the mainstream Corporate Media refuse to discuss. What politicians do. Put themselves on the line to get accepted or rejected. So when you want to be president. Or somehow want to. Have to go right to the press this is what the 43 of the more people. Im interested in always in the waters of our. Friendship. Welcome back i am a have begun with threats to life on earth coming from war catalyzed by us assassinations and Climate Change destruction seen across australia but some scientists are asking not so much about the end of life on earth or even the origins of life on earth but what is life itself joining me is Award Winning professor paul davies whose new book the demon in the machine the hidden webs of information is solving the mystery of life is out for welcome to going underground so who are the demons of James Clark Maxwell well maxwell was a giant of theoretical physics lived in the 19th century where its not very far from webb is sitting at Kings College in london unified electricity and magnetism and contributed enormously its of the theory of heat and he. With the weird idea in a letter to a friend it was just an idle thought that if there was some sort of tiny little being who could see individual molecules as they rushed around colliding with each other and could have some sort of shot a mechanism to manipulate where they went then without expending energy could accumulate all of the fast moving bollock your was ever here all the slow moving molecules over there so this will get hotter than that and any competent engineer can tell you if youve got a temperature difference you can run an engine off it a heat engine and do work so max will seem to come up with a sort of perpetual motion machine something where just by using the information of the molecular motions you could produce a source of work a type of fuel information as a type of fuel very radical idea since the paradoxical of the time mazing about this book of course is then you use that to talk about the definition of life why do you think it is that we dont have a definition of life people do presume what it is you say in the book when a mouse is dead you know its 90 percent alive nobody can really say what life is or how it began and there are plenty of books about what life does but this is a book about what life is about living matter how does living matter differ from nonliving matter current scholarship. Is and you explore that is its about information yes so the key to understanding the difference in living and nonliving and to unify these 2 great here is of science physics on the one hand the biology on the other is this concept called information but its also an abstract concept and its branch of science called information theory thats about 60 or 70 years old. And that treats information a little bit like the concept of energy we use energy in everyday life we talk about it in sort of colloquial terms but we also know it has a technical definition as an abstract quantity that can be passed from one system to another and its always conserved something with information and we know that life is invested in information because d. N. A. For example is like the rulebook of life its an instruction manual to build an organism but thats only just the start if we think about gene as set of instructions for something to happen building a protein for example genes coupled together to form complex networks that switch each other on and off information swirls around these Networks Information is transferred between cells signal each other and then theres that great information process between areas thats probably the best example people can think of as biology vested in information and Information Processing so its a very bad biology but its not there in physics when you think about you know what is an atom doing processing information well you know its that some sort of sitting there in a collection of atoms. Dont have anything like a purpose or goal and yet living organisms do so somehow information is the glue that is going to unite the world of physics in the world of biology is as huge relevant to the treatment of cancer before i would. You about it you retell it here story where yuri loves a big which is kind of relevant to this i think we say can a biologist fix a radio you might have to explain that which is why its taken so long for us to get to where we are today thats a wonderful essay and the essence of this is that as we now understand it when you think of a of a cell its really a collection of modules and functional components if we think less about the individual molecules more about the signals and the information flow inside the system. And thats exactly the sort of approach you would take with a radio now let me give an example the particular essay referred to a transistor radio and say you had all these components together and if you went wrong for example you had a distorted sound well how do you fix it and you wouldnt go about fixing it by examining the atomic structure inside a transistor on something you would know that there are certain rules of radio rules with electronics and you could fix it a competent. Radio technician would be able to identify 40 component and rewire it a tweak it and and fix it up if you try to to understand whats gone wrong for example in cancer whats gone wrong well its just a me tayshaun on this particular gene this is a very and i had to quit picture we have to try to understand it in terms of Like Electronics of modules wired together of circuits the around which information swirls of these circuits can become distorted or unbalanced. When political biological theme especially most evangelical christians in the United States were a i do you teach has been darwin if the if one of them picked the book. Brenda when it opened it to see that you were costing down to at least showing that you had doubts on that over 3 or 4000000000 years the human eye could have been created by joe we need a Natural Selection just tell us a little bit about that agenda which obviously saying that we need evolution is wrong not to say there is a there is a crucial problem and i think this is why they reckon i mean its not wrong its just slightly an adequate in that case case of gravitation we need einsteins general theory of relativity which is a refinement of that and i think darwinian evolution his original theory has done wonders and so theres a whole chapter devoted to the new biology which is going beyond that and in particular the field of epi genetics as its called which is those aspects of the g. Which not capture the genetic level but which are very very important for the way the system behaves these impulses that is now being widely recognised but this is still a battle theres still some die hard reductionist series say that ultra pure original darwinism is the only way to go and the difficulty you as you rightly mention in the United States is if youre dealing with people who want their religious interpretation of what miracles to put it bluntly is that if you give the slightest impression while theres a problem about the original formulation of darwinism they pounce on the but this is a cause for theologians call the god of the gaps just because its might be able to explain something but the fact that sounds counter explain that theres a gap in our understanding that doesnt mean we want to rush in with god to fill that gap we need a miracle we dont need a miracle we need better suns a better understanding of you the very serious nature of this book and you leave it till the end after talking about information and what the definition of life is impractical to us is the treaty. And of cancer. We made off with the evangelical right about their views but actually you seem to be suggesting that a lot of biologists to be believe in a miracle cure for cancer which is not the panacea that they should be looking for yes i think Cancer Research is a very good example of how over conservative thinking in biology has not led to lack of progress but the progress has been much less of a 2nd biggest killer. Cancer is has also had to become the worlds number one killer touches every family on the planet and its a city tragic of course and people are scared of it and they want something to be done about it i think theres been this naive view that if we just throw enough money at the problem well discover a pill that will just make it go away and thats never going to happen as we have to be much more subtle in our approach to treating cancer newsgroup sinister ugly when you read the book is us saying that using all this information 80 years is a definitive look there is something intrinsic about life in cancer yes its the nature its the nature of multicellular life cancer is sort of written into the whole. Logic of life 2000000000 years ago there were just single celled organisms on this planet and a bacterium for example just has one imperative replicate replicate replicate its ineffective mortal and then about one half 1000000000 years ago life organized itself rather differently than these some organisms did ensue multicellular collected some what happens there in order organisms like selves is that individual cells give up their individual immortality they outsource that immortality to special germ cells likes eggs and sperm and they carry the information. Legacy into the next generation and the individual socalled somatic cells like a cells in a skin and liver and so on they part of that contract is that they undergo programmed cell death called a pup texas and cancer is a breakdown of that ancient contract in which the individual cells return to a bid for immortality worrying about that is. This is all going to be a magic pill for cancer there when each individual cancer has to be treated in the same way a general purpose pill to make it go away i think is is youre on a hiding to nothing if you think a lot of the problem live is being capitalism the position of profit Big Pharmaceutical Companies saying weve got to look for this pill because a budget a rich would become i think youre right that the funding model where whether we call it capitalism because it is after all rigged market anyway. Or over conservative government investments in cancer i should should mention that i was funded for 5 years by the Us National Cancer institute spends 5000000000. 00 a year on cancer and. When i look at how that spends a lot of it is just spent on sort of same old same old Mainstream Research very little on imaginative new approaches and the approaches im outlining in the book. Has received some funding but its a sort of tiny fraction and so there is deep conservatism in the Cancer Research community. And i give you an example which relates directly to the whole profit business that of course. If you have some way of combating cancer like through diet or. Another approach that weve looked at is hyperbaric oxygen therapy which is pretty patients in 2 atmospheres of pure oxygen for a short period the some belief that. Some evidence that this is efficacious so one of the most efficacious anti cancer drugs its well known in the Cancer Community is aspirin but you know its fair to be free over the counter and so getting Clinical Trials for things like aspirin is not easy there have been some. But and will be will say this is. It isnt that because well believe it is possible davis thank you and bouts of the show would go when say 50 years to believe more modest after becoming Prime Minister of libya until they can be judged by social media dont forget to subscribe to our you trust. Descriptions sound up to tell using even for the owners. How to choose pet Food Industry is telling us what to feed our pets really more based on what they want to sell us than was necessarily good for the pet turns out may not be. People believe we have animals that have you know diabetes in arthritis they have auto immune disorders allergies we are actually creating these problems its a huge epidemic of problems all of them i believe can be linked to very simple problem of diet and some dog owners so heartbreaking stories about their pets less treats a larger corporations are not very interested in proving or disproving the value of their food because theyre already making a 1000000000. 00 on it and theres no reason to do that research. Sex drugs or financial survival. When customers go buy your supplies. Then else well reduce some lower. Thats undercutting but whats good for market is fuck good for the global economy. Is a mighty along. Side them that want to listen to the bomb was more about. What win there. But in the same. Scene that. Donald trump tweets on assassinated. Saying that even if he was not a threat to the u. S. Or the iranian generals track record sealed his fate. The leaders of libyas the warring factions are in moscow for ceasefire talks brokered by russia and turkey it is hoped the war torn nations rival administrations will sign an agreement on tuesday. And e. U. Funds to boost infrastructure in east africa and prevent Mass Immigration to europe is in the firing line for driving modern day slavery we speak with a Human Rights Watch representative on the claims. To have absolutely no choice