In all of the rest of life combined, that is a quote by late renowned american biologist Edward Osborne wilson, just to highlight how important taking care of the health of the of animals in animal husbandries is. After all, if the animal has a disease when slaughtered, its very likely that it will be affected by its one way or another, but more often than not, sick animals dont infect humans, but as a result of cross species infection, or viral host jumps, it can still happen, and when it does happen, it has the potential to produce deadly epidemics, and no, im not going to beat a dead horse and say, we know thats too of well. Livestock, pultry and fish are all susceptible to various viral, bacterial and fungal diseases of all types, which not only requires different drug formulations, but also different dosage forms, has in the medium through which the drug is administered drugs can be administered to animals as solids or liquids mixed in with their food or through injections along with other less common forms. These drugs are meant to combat various types of parasites, infections and sometimes simply inflammation and discomfort. In this episode were going to cover some of these drugs across different forms of dosage forms, particularly the four drugs that only this facility makes in one, which is located in the city of aza. Now asna is located in lotason province to the west of ewan and has population of around 50,000 and has fair of industrial sites, particularly when it comes to mineral extraction and processing. The drugs made in this facility cover a wide range of dosage forms qu seven production lines, producing total of 110 different types of drugs. One production line covers injection viles, another specifically for different types of penicillin, this is prime penicillin benz. Penicillin, ampacillin and more, and then there are liquid drugs, sterilizing pointmens and semisolid sachets. Were going to get indepth look at these four different types of exclusive drugs and talk about what they do, what they contain, and what kind of infections or inflammations they attempt to combat. So this is the part where they package the liquid solutions that are meant to be taken orally by the animals, but there are a couple of liquid solutions that are not meant for. Oral use, and those are the duramectinebased and levamisolbased drugs that are right here, so they are made in the same facility, but they are not meant for oral use, they are actually meant for as a poron solution to be rubbed on the skin of the animal uh for it to then be absorbed by the skin and have its effect in the inside of the body as well, so im going to start with uh, actually both of them have antiparasitic effects, im going to start with the levamisol solution, so uh levamisol. 20 solution, the difference that it has with the cot ones that are at 7. 5 , because of the hot toxicity levels of regular level based solutions, you cant really have a High Percentage in that solution, thats why the percentage is so low at 7. 5 when there when its taken orally because of the high toxicity level, but in in this particular format of use in the uh poron solution we can have a a higher percentage and a higher level of effectiveness uh, because the toxicity that is meant for respiratory, that is going to cause respiratory problems for the animal is not going to be absorbed as much, so we can have a higher efficiency, higher percentage level solution, and this also it has the added advantage of getting rid of external parasites as well, whereas the oral solution is only to get rid of internal parasites in the respiratory and digestive system, but this can also get rid of external parasite now uh lets get to this one, the duramectine based drug, so the duramectine based drug is based off, its its like a third iteration of the ivermectan drug, under the name of hydro under the commercial name of hydroch hydro hydroxychloroquine im sorry the name was a really difficult is the same drug that was prescribed by former us President Donald Trump as solution to protect the average person against the coronavirus whereas this was meant for injection to horses and other ruminant animals to protect them against um different types of parasites so theres that this Third Generation of iver mecat. The difference that it has mainly with the first generation of ivermectin is in the waste, so the waste of ivormectin was really dangerous for the environment around the factory and also particularly for marine uh because of the toxicity levels, but this one uh because of the large molecules that it has and the large amino molecules that it has, it doesnt really react with water all that much and thus it is much safer for marine life, so thats the main difference with this one compared to regular ivormexen, so thats two the. Drugs that only this Company Makes in iran, but there is more and were going to check them out as well. And this is the end the production line for the injection viles and over here, i have one of the other exclusive injection viles, exclusive drugs that they made here, so this is called bymethocin, which is a suspension, which is based a mixture of sulphodiozin and trimotorin, so the reason this is a suspension instead of solution, this is a 48 suspension instead of the typical 24 solution, and what that does is that it allows us to have a higher percentage of substances that we want to inject in the body the of the cattle, so in the instructions of this particular vile, it says 1 milligram per 30 kilograms of cattle, so a 300 kilotle will take 10 ccs, and that means one simple injection, whereas in a 24 solution that would require multiple. Injection, it take like 30, 40, maybe 50 ccs of a 24 solution, so thats why we have made it in the suspension form, and thats the exclusive part, its the form of injection, how theyve managed to get to the suspension that is the difficult part, so thats as far as the uh suspension goes, this bimitosine, and over here, this is called massilas, its an ointment that is injected inside the teeth of lactating cow, so there are other ointments that are meant for periods when the cow isnt lac. Tating and that in combination with this uh is going to be is going to have antiinflammatory properties and the important thing with this particular ointment is that uh it is nonsteroid based there are other uh like for example we have dexamato zone which has also antiinflammation properties but it is steroid based and when a cow is undergoing pregnancy you cannot use that to uh protect it protect it against inflammation because that would be potentially fatal for the cath, whereas this is nonsteroid based, so it has a combination of penicillin g procain, dehydrostreptomycine, neomycine and prednizolon, and none of these have uh steroids in them and actually three of them are antibiotics and thats how it gets the antiinflammation properties. So that was the final exclusive drug that they make here uh, but there is still other information that we need to learn about this facility. To find more about what makes it possible for this factor to be able to produce exclusive drugs that no one else can make in the country. I am with the factory manager, ahmad haidary and the question that i have from in first and foremost is that uh, what is the uh process, what are the factors that need to be met to let you be able to make these exclusive drugs . Considering the Technical Knowledge and the experts we possess here in bioraflow. Certical company, we have been able to make four recombinate medicines for the very first time in Islamic Republic of iran. These drugs are exclusively produced in by aflock company. We have been able to produce these drugs thanks to reverse engineering, and other domestic Pharmaceutical Company has been able to produce such drugs. We have produced such good drugs by implementing some changes in mis. Of course, in order to be able to create this many different types of drugs at this scale, you need to go through some procedures and acquire certain standards and certificates. Can you tell me about those . Bioraflock Pharmaceutical Company has acquired various certificates and two of them are pretty significant. One of them is fda from usa, which has enabled us to export our products very easily. The other significant certificate is 17025 which is given to us for our laboratory to accept us as their lab partner. Lab partner means that if there is any customer complaint about other pharmaceutical units regarding the equipment we have here. Uh thank you very much ahmad for your information uh to some closing thoughts. So i hope youve all learned a thing or two about the process that goes on behind manufacturing different types of drugs and the safety procedures that also go behind them uh and now with the economic and political doors that have been opened to iran we can only hope for exports to go up exponentially so heres hoping for that to happen and with that said weve come to the end of this episode hope to see you all in the next week. The Islamic Republic of iran strategic agen unfirled at the 70th session of the United NationsGeneral Assembly in new york. Emerging eastern powerhouses and the new world order. President Ibrahim Raisis policy to promote Regional Security and cooperation. Irans pibotal role in west asia and the worlds and more all on this edition of iran today. I was born in 1971 in jerada, i love physics, because its allow me to understand the fundamental laws that govern the matter and the universe, my name is yahya tayaalati, im professor at the university. During my master study in one of the prestigious theoretical physics lab in morocco in rabat, i was really impressed by the work of professor Muhammad Abdul salam, i was also deeply, i would say influenced by the story of these professors and all the effort he has made to help science in. Muslim country and also the dream to be able one day to, i would say to bring some knowledge and transfer some technology to my country in morocco. I think we we got this award for our contribution both in high energy and astroparticle physics. Uh, too recently, our group was involved in the search. The light by light skatering, its a process which is completely forbidden by classical electrodynamic, but it appear in quantum electrodynamic, but its extremely rare, thats why many devices has been proposed and they all fail, by using what we call the ultraperipheral collision between heavy eye. At the lhc, because lhc collide protons, but it collide also lead lead ions, the electromagnetic field get enhanced due to its dependency of the charge of collided ion, and this enhance also the probability, which the Cross Section of this process and we have managed to measure like 59 events of this kind of light by light scatering. While expecting only 12 background event, and this was the first time that we observe this this important process. What make light by light scattering an important process is the fact that the scattered photon could couple to any exotic particle beyond the standard model and we have here a clean way to prob for new physics beyond the standard. Model, morocco has been selected like the sixth site to assemble this High Performance detector. Which is one of the fastest one in the in the world, it touch the Horizon Technology because it ensures Something Like 30 pick second of time resolution, which is also here very important for our country, transfer of technology and also high quality, high level training from for our phd student, the the first time heard about the mustafa prize was like a bit more than two years ago from social media so i visited the their website once and googled the the web pages of the different previous laureat and i was impressed by their achievement but to be honest i did expect that it will happen one day i mean i am was surprised but very. Honor to get this prestigious award, yes. Your headlines here on press tv, bomb blast near a mosk in southwest pakistan leaves dozens dead and many more wounded. Bricks group of nations plans a financial messaging system to enable Member States to conduct trade in local currencies and a government shut down looms in usa. Congress is yet to offer a clear plan to fund federal agency