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Neoadjuvant treatment with fluorouracil, leucovorin, and oxaliplatin proved to be as effective as pelvic chemoradiation with fewer adverse effects in patients with locally advanced rectal cancer who were eligible for sphincter-sparing surgery.

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United States ,New York ,Pamelal Kunz ,Georgej Bosl ,Deb Schrag ,Department Of Medicine ,Memorial Sloan Kettering Cancer Center ,Cancer Care ,

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