AP Photo/John Locher
FILE - In this Jan. 22, 2021, file photo, empty vials of the Pfizer-BioNTech COVID-19 vaccine are seen at a vaccination center at the University of Nevada, Las Vegas, in Las Vegas. The makers of COVID-19 vaccines are figuring out how to tweak their recipes against worrisome virus mutations — if and when the shots need an update.
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The coronavirus vaccine rollout in Pennsylvania has created frustration for state officials and residents alike, with counties creating online registries to help get constituents the information they need and hospitals struggling to minimize wasted vaccine doses.