The defender is pleased to join the Red and Whites and looks forward to helping the club win more trophies.
“The first impressions here with PSV are very good. The stadium and training facilities are just great,” Mwene told the club website.
"PSV is a big club that wants to win prizes and fight to the end in the title race. And that’s the new challenge I was looking for.
“I will give everything on the pitch. I am looking forward to being part of this club.”
PSV director of football John de Jong believed the full-back will bolster his side and praised his versatility.