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Paramedics are treating patients at the scene of three-car crash on the Bruce Highway southbound, near Elimbah.
It is unknown how many patients are involved in the crash, which occurred at 1pm, just prior to the Caboolture-Bribie Island Road exit.
A QAS spokesman said one ambulance crew was currently on scene.
Drivers were advised to proceed with caution, but delays were not expected.
One patient has been taken to Nambour Hospital in a stable condition following a two-car crash in Maroochydore this afternoon.
The crash occurred on Thomas Street and Bradman Ave at 12.30pm, with only one patient requiring transport to hospital.