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One in four people experience mild, short lived systemic side effects after receiving either the Pfizer or AstraZeneca vaccine, with headache, fatigue and tenderness the most common symptoms. Most side effects peaked within the first 24 hours following vaccination and usually lasted 1-2 days.
The study published today in the
Lancet Infectious Diseases is the first large scale study to compare the two vaccines and investigate the prevalence of mild side effects of the UK's vaccination programme.
The analysis by researchers from King's College London of data from the ZOE COVID Symptom Study app reassuringly found much fewer side effects in the general population with both the Pfizer and AstraZeneca vaccines than reported in trials.

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