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“This includes studies for cancer, reproductive impairment and other adverse effects called for by FDA’s Redbook, the Bible of food and color additive testing. We find this to be all the more troubling because a number of potential adverse effects were detected in a short-term rat trial: disruption of reproductive cycles and reduced uterine weights in females and biomarkers of anemia, reduced clotting ability and kidney problems.” (CFS).
To make the GMO heme, Impossible Foods uses what is called "synthetic biology" which extracts DNA from the roots of soy plants where a small amount of heme is produced. They then insert that DNA into genetically engineered yeast. The yeast ferments and that process mass-produces the genetically engineered heme.