Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

All normal human tissues acquire mutations over time. Some of these mutations may be driver mutations that promote the development of cancer through increased proliferation and survival, while other mutations may be neutral passenger mutations that have no impact on cancer development.

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Chandler Gatenbee ,Alexander Anderson ,Ryan Schenck ,Emily Henderson ,Proceedings Of The National Academy Sciences ,National Cancer Institute ,Wellcome ,Wellcome Centre For Human Genetics ,Moffitt Department Of Integrated Mathematical Oncology ,Moffitt Center ,Moffitt Cancer Center ,National Academy ,Integrated Mathematical ,Wellcome Trust ,Wellcome Centre ,Human Genetics ,Cell ,Revolution ,Skin ,Dancer ,Ell Death ,Epidermis ,Gene ,Laboratory ,Ncology ,Mh ,Proliferation ,Research ,Skin Cells ,Stem Cells ,