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Bengaluru (Karnataka) [India], January 25 (ANI/PRNewswire): A 34-year-old Suma (name changed), diagnosed with Homozygous Familial Hypercholesterolemia (HoFH) since 2014 was referred to Manipal Hospital, Old Airport Road, Bengaluru. HoFH is a condition where two abnormal genes one from each parent is inherited by the patient. This leads to very high levels of bad cholesterol which deposits in the blood vessels leading to heart disease and premature death. Our patient too developed cardiac symptoms and was referred to Dr Devananda N S, Head & Consultant - Cardiothoracic Vascular Surgery and Lung Transplant Surgery, Manipal Hospital Old Airport Road, Bengaluru for bypass surgery of the heart in 2021. Following the surgery she was referred to Dr WG CDR S.S. Iyengar, Consultant - Cardiologist, Manipal Hospital Old Airport Road for further management and was treated with statins and lipid-lowering agents. She had suffered a miscarriage at 7-8 weeks gestation during her first pregnancy in 2018. She conceived again for the second time in early 2022. In view of the high-risk pregnancy, the lack of efficacy and inability to use some drugs in pregnancy, lipoprotein apheresis procedure was considered by Dr S.S. Iyengar and the patient referred to Transfusion Medicine department. Lipoporotein apheresis is a procedure akin to dialysis, where the patient's blood is passed through a cascade filter which removes the bad cholesterol and returns the filtered blood (plasma) back to the patient. Since the production of cholesterol in the body is a continuous process the procedure has to be repeated fortnightly to keep the cholesterol levels under check. A total of 5 procedures each costing approximately Rs 75,000/- per session were done free of cost to the patient starting from 22 weeks owing to the support from the Manipal Hospital Management and Lipid Association of India who sponsored the drugs free of cost. In view of the cost constraints the procedures were spaced at 1-month intervals until delivery. Vascular access for the procedure was secured with the help of Dr Sridhara G, Consultant - Interventional Cardiology, cardiac Electrophysiology and the procedures carried out by Dr C. Shivaram, Consultant & Head - Transfusion Medicine, and Dr Ambuja K, Associate Consultant - Transfusion Medicine. Fetal monitoring during procedure and obstetrical care was provided by Dr Gayathri Karthik Nagesh, HOD & Cosultant - Obstetrics & Gynaecology. A healthy baby was delivered at term, by caesarean section on 6th Jan 2023 and both mother and child are doing well. Neonatal care was provided by Dr Karthik Nagesh, Chairman & HOD, Neonatal ICU and Manipal Advanced Children's Centre. But for the efforts of Dr S.S. Iyengar, the primary physician who cared for this patient from end-end, this baby would not have seen the light of day. Lipid apheresis is a very rare procedure and to the best our knowledge Manipal Hospital, Old Airport Road, Bengaluru is the first to do this in pregnancy in the country. In all lipoprotein apheresis procedures the cost of the filter which is as expensive as Rs 50,000/- and plasmapheresis which cost about Rs 10,000/- are the limiting factors. Most of these patients cannot afford the filter and need help from the government and philanthropic organizations. This story is provided by PRNewswire. ANI will not be responsible in any way for the content of this article. (ANI/PRNewswire)

Related Keywords

Manipal ,Karnataka ,India ,Bengaluru ,Karthik Nagesh ,Gayathri Karthik Nagesh ,Lipid Association Of India ,Transfusion Medicine Department ,Manipal Advanced Children Centre ,Homozygous Familial Hypercholesterolemia ,Manipal Hospital ,Old Airport Road ,Vascular Surgery ,Lung Transplant Surgery ,Manipal Hospitalold Airport Road ,Transfusion Medicine ,Manipal Hospital Management ,Lipid Association ,Associate Consultant ,Manipal Advanced Children ,Bengaluru Karnataka India ,Anuary 25 Ani Prnewswirea 34 Year Old Suma Name Changed ,Iagnosed With Homozygous Familial Hypercholesterolemia Hofh Since 2014 Was Referred To Manipal Hospital ,Engaluru Hofh Isa Condition Where Two Abnormal Genes One From Each Parent Is Inherited By The Patient This Leads To Very High Levels Of Bad Cholesterol Which Deposits In Blood Vessels Leading Heart Disease And Premature Death Our Too Developed Cardiac Symptoms Was Referred Dr Devanandan S ,Ead Amp Consultant Cardiothoracic Vascular Surgery And Lung Transplant ,Manipal Hospital Old Airport Road ,Engaluru For Bypass Surgery Of The Heart In 2021 Following She Was Referred To Dr Wg Cdrss Iyengar ,Consultant Cardiologist ,Anipal Hospital Old Airport Road For Further Management And Was Treated With Statins Lipid Lowering Agents She Had Suffereda Miscarriage At 7 8 Weeks Gestation During Her First Pregnancy In 2018 Conceived Again The Second Time Early 2022 View Of High Risk ,He Lack Of Efficacy And Inability To Use Some Drugs In Pregnancy ,Ipoprotein Apheresis Procedure Was Considered By Drss Iyengar And The Patient Referred To Transfusion Medicine Department Lipoporotein Isa Akin Dialysis ,Here The Patient 39s Blood Is Passed Througha Cascade Filter Which Removes Bad Cholesterol And Returns Filtered Plasma Back To Since Production Of In Body Isa Continuous Process Procedure Has Be Repeated Fortnightly Keep Levels Under Checka Total 5 Procedures Each Costing Approximately Rs 75 ,000 Per Session Were Done Free Of Cost To The Patient Starting From 22 Weeks Owing Support Manipal Hospital Management And Lipid Association India Who Sponsored Drugs In View Constraints Procedures Spaced At 1 Month Intervals Until Delivery Vascular Access For Procedure Was Secured With Help Dr Sridhara G ,Consultant Interventional Cardiology ,Ardiac Electrophysiology And The Procedures Carried Out By Drc Shivaram ,Onsultant Amp Head Transfusion Medicine ,Nd Dr Ambuja K ,Ssociate Consultant Transfusion Medicine Fetal Monitoring During Procedure And Obstetrical Care Was Provided By Dr Gayathri Karthik Nagesh ,Od Amp Cosultant Obstetrics Gynaecologya Healthy Baby Was Delivered At Term ,Y Caesarean Section On 6th Jan 2023 And Both Mother Child Are Doing Well Neonatal Care Was Provided By Dr Karthik Nagesh ,Hairman Amp Hod ,Eonatal Icu And Manipal Advanced Children 39s Centre But For The Efforts Of Drss Iyengar ,He Primary Physician Who Cared For This Patient From End ,His Baby Would Not Have Seen The Light Of Day Lipid Apheresis Isa Very Rare Procedure And To Best Our Knowledge Manipal Hospital ,Engaluru Is The First To Do This In Pregnancy Country All Lipoprotein Apheresis Procedures Cost Of Filter Which As Expensive Rs 50 ,000 And Plasmapheresis Which Cost About Rs 10 ,000 Are The Limiting Factors Most Of These Patients Cannot Afford Filter And Need Help From Government Philanthropic Organizations This Story Is Provided By Prnewswire Ani Will Not Be Responsible In Any Way For Content Article ,

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