Ipswich Road is shutting from its junction with the Ipswich Road roundabout to Old Coach Road.
The closure is due to last for two nights from April 30, between 8pm and 6am.
It is while high-friction surface application works are undertaken by Essex County Council.
An alternative route is available via Ipswich Road, East Street, Harwich Road, the Harwich Road roundabout, St Andrews Avenue and the Ipswich Road roundabout.
* Drivers should look out for new speed restrictions in Boxted.
New 20mph zones are being introduced on the following lengths of roads - Hill Farm Way, from its junction with Carters Hill, and Pippin Drive, from its junction with Hill Farm Way.