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BOSTON - Adding an immune checkpoint inhibitor to the standard chemotherapy regimen for patients with early-stage breast cancer places no greater burden on patients' ability to perform day-to-day activities than chemotherapy alone, new research by Dana-Farber/Brigham and Women's Cancer Center investigators shows.
The report, coupled with earlier findings that combining checkpoint inhibitors with chemotherapy can increase response rates in patients with early-stage triple-negative breast cancer, offer assurance that the benefits of the combination can be achieved without diminishing patients' quality of life, the study authors say. The study, to be presented at today's virtual session of the San Antonio Breast Cancer Symposium, by Elizabeth Mittendorf, MD, PhD Director of the Breast Immuno-Oncology program at the Dana-Farber/Brigham and Women's Cancer Center, is the first to use patients' own feedback to gauge the impact of the combination therapy on daily functioning for patients with early-stage breast cancer.