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In 2017, the World Health Organization published a list of pathogens for which new drugs are urgently needed. Acinetobacter baumannii was ranked in the critical priority group along with other Gram-negative bacteria such as Pseudomonas aeruginosa and carbapenemase-producing Enterobacteria. Specifically, A. baumannii is responsible for more than 10% of hospital infections, often severe, such as pneumonia linked to mechanical ventilation, and bacteremias, especially in intensive care units.
The 'Bacterial and Antimicrobial Resistance' group at the Institute of Biomedicine of Seville, led by Dr. José Miguel Cisneros, has published the results of a collaborative preclinical study focused on this specific pathogen. The study was conducted together with the 'Emerging Antibiotic Resistances' group, headed by Prof. Patrice Nordmann from the University of Fribourg, Switzerland.