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RA is the result of an immune response in which the body’s immune system attacks its own healthy cells, especially the lining of the joints, known as the synovial membrane, or synovium, causing an inflammatory response (Centers for Disease Control and Prevention, 2020). The disease can lead to premature mortality, disability, and decreased quality of life due to bone erosion and joint deformity (Brooks, 2006; Centers for Disease Control and Prevention, 2020).
The epidemiologists utilized county-specific studies published in peer-reviewed journals to build the forecast. The publisher’s epidemiologists used sources that confirmed RA cases based on the American College of Rheumatology (ACR) criteria and International Classification of Diseases, Tenth Edition (ICD-10): M05 and M06, in order to ensure a uniform case definition across markets. The report includes a 10-year epidemiological forecast for the diagnosed incident and prevalent (total and diagnosed) cases of RA in the 8MM, segmented by age, sex, and severity.