Researchers from the University of Helsinki and HUS Helsinki University Hospital have achieved a significant medical breakthrough by successfully correcting a genetic defect that causes a hereditary metabolic disease, thus mitigating its harmful effects on cells. This landmark research focused on Argininosuccinic Aciduria (ASA-uria), a severe metabolic disorder prevalent in the Finnish gene pool, where the body fails to process proteins properly, leading to dangerous accumulations of ASA and ammonia. Excessive ammonia can cause disturbances in consciousness, coma, and even death.