His family asked for privacy.
Qwelane was appointed South Africa's ambassador to Uganda in 2010.
Former ambassador, journalist and activist Jon Qwelane has died.
Qwelane's attorney, Andrew Boerner, confirmed his death to News24 on Thursday morning.
Boerner said the family asked for privacy during this time.
Qwelane was appointed South Africa's ambassador to Uganda in 2010.
In 2008, he wrote an unpopular opinion about same-sex marriage in the now defunct Sunday Sun, titled: "Call me names, but gay is not okay".
He also lauded former Zimbabwean president Robert Mugabe's "unflinching and unapologetic stance" on homosexuality.
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"There could be a few things I could take issue with Zimbabwe President Robert Mugabe, but his unflinching and unapologetic stance over homosexuals is definitely not among those," the column read.