League leaders Yanga SC, who were bundled from last year's edition in the semis by their rivals Simba, have a relatively easier task against Kengold FC.
Another interesting fixture will be between Mtibwa Sugar and JKT Tanzania as well as Mwadui FC who will host Gwambina FC.
Administrative side Ruvu Shooting have been handed a task against former top-tier side Mbao FC. The latter will be at home and will be aiming at capitalizing on the home ground.
The winner of the competition will represent Tanzania in the Caf Confederation Cup competition in the 2021/22 season.
Meanwhile, Namungo will play Primeiro de Agosto of Angola in the final preliminary round of the Caf Confederation Cup. The FA Cup finalists, who are making a first appearance at this stage, will play away before a home match against the Angolan outfit on February 12 and 21.