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MEMPHIS, Tenn. - Extremely low birth weight (ELBW) infants with moderate to large patent ductus arteriosus (PDA) may benefit from transcatheter PDA closure (TCPC) in the first four weeks of life, according to research published by Le Bonheur Cardiologist Ranjit Philip, MD, and Medical Director of Interventional Cardiac Imaging and Interventional Catheterization Laboratory Shyam Sathanandam, MD. Early PDA closure may prevent early onset pulmonary vascular disease, promote growth and facilitate faster weaning off supplemental oxygen and ventilator support.
"The primary objective of this study was to describe changes in hemodynamics, respiratory support and growth associated with TCPC in ELBW infants," said Philip. "We also wanted to describe clinical outcomes in early versus delayed PDA closures to identify factors associated with worse clinical outcomes."