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Maduro claim things sweeping election victory after less than a 3rd of the country turned out to vote as the countrys economic crisis deepens what when mean for venezuelans struggling simply to survive. Im brinkerhoff its good to have you with us tonight time is quickly running out to make a post break sit trade deal the reality british and european negotiators have once again been locked in talks for hours today with no sign of a breakthrough now british Prime Minister Boris Johnson is set to head to brussels for a last ditch attempt to reach a deal to ease chief negotiator Michel Barnier is downbeat about the chances of an agreement saying key sticking points remain. Despite growing fears of economic chaos of britain leads without a deal london has said that it will not extend the negotiations. Hard for more now we want to bring in our correspondent in brussels barbara they saw in charlotte just until in london good evening to both of you barbara let me start with you lets start with brussels here what is happening right now in brussels absolutely nothing because another day has come and gone with the results Boris Johnson and or sort of underlying the e. U. Commission chief had a phone call lengthy phone call this evening after an hour and a half they gave threw up their hands and said were getting nowhere they must have been the rating each other without really being able to move anything now the negotiators are supposed to take stock of the remaining. Grave divergences and then Boris Johnson will be heading to brussels now there is a nice of the unity for him on thursday because thats the day when the e. U. Leaders have some and planned anyway bought on the other side they may not want to receive him and they may in the end sort of relegate the these talks to a slough underlying the that commission chief and then he will have to talk through her and then back to the Member States so we will see how this plays out but obviously there is political will needed now at the very top to sort of figure out whether this will be a no or yes and charlotte we have seen this many times before are we now finally reaching in game. Thats right we can say count on many hands the amounts of times that weve talked about deadlines that have come and gone for a resolution to these trade and security negotiations now it appears another one now earlier in the day chief negotiator of the e. U. Michel barnier had said earth it took to continue until wednesday and no further will be it remains to be seen now whether or not or that meeting in brussels will be beyond wednesday whether that is in fact the final deal in fact downing street a short time ago here in the u. K. Hand said that they will continue talking until the last minute while they still think a deal can be achieved indeed both sides have said in various points that they will they will keep talking as long as it takes while they think that that can be done in the meantime the people here in the u. K. Watching these negotiations some with dispatch others fatigue as they see yet another deadline come and go these negotiations in some form or another 30 u. K. Earth of wrecks that have been going on for years now take a listen to what some people arabs on the streets in the u. K. If i had to say im not worried about it because we need to get something so detailed. We need to make a deal. They dont have to give in to what we should what they want to do so i could be buried in the public to know about this and whats going on but if buried among them down behind them a firing back and you come up to 76 i dont know how many people realize or break a meeting i saw you mean this is why i would want to know your situation and i dont like the fact that the government has made on what they promised i think is very unfair. People seem crazy i mean 2016 we rotate in 4 years later and i have but i think if i didnt progress at all to be honest with you personally i think no deal is probably better than a fair deal with just what the reasons are you have said all along. Who knows whats going to happen but i think even though you know to be honest with you. Now some optimists might say that this is all part of the drama what you might expect with the end of these negotiations both sides showing that they are fighting as hard as possible for their respective audiences but the fact is now we are just a fish 3 weeks away from the end of the transition period thats the period at which on december 31st the u. K. Finally cut ties with the with the European Union both sides have said of course that they would like a deal but they wouldnt like a deal and any cost. What happens if the come to december 31st and they havent reached a deal what happens then on the business side of things they call this armageddon day what will happen is that 40 years of cooperation of the free Flow Movement of goods People Services money between the 2 sides across the channel will end all of a sudden overnight and cracks will stack up to the rising and supposedly cheers will flow. Are brussels in charlottesville some fill in london to both of you thank you. Its hard staying in the u. K. Now and hospitals across the country are preparing to start coronavirus vaccinations on tuesday britain will be the 1st country in the world to roll out the buying on tech pfizer Coronavirus Vaccine for at Line Health Care workers people over the age of 80 and care home employees will be prioritized in england 50 hospitals have been initially chosen to serve as hubs for the launch of the largest Immunization Program in british history. This is a moment the whole worlds been waiting for the u. K. Is the festival now its the bio and tech pfizer 1000 vaccine its in the mentors may than to repopulate in with the highest death toll in europe and off is a window of hope for the future. Very very sadly lost many residents of those care homes who died from co theres been a huge challenging and difficult year and all the time this promise and this hope of a vaccine has been so its very exciting to the point where feels like that we might be able to make a really positive step or with the help of the facts. The u. K. Health service is calling this the biggest Immunization Program in its history 1st in line for the vaccine will be people over 80 as well as care home staff and frontLine Health Care workers but this rollout poses major logistical challenges this vaccine needs to be stored at around minus 70 degrees celsius and needs carefully meaning in england it will at 1st only be administered from 50 specific hospital hubs. Is the 1st in the well truth arise the vaccine the u. K. Is dependent on public trust and enthusiasm isnt universal risk is what the long term effects bring thanks i would take it. Is a benefits outweigh the risks seems sensible thing to do and its the only way were going to add to the pandemic i think is very very fast i was come out. If i trust it i would say can at. Least of us see. You thanks if you cheat on facebook up sacred the vaccine will be key to success and authorities are being advised to find creative ways to address public concern and talk of misinformation theres some speculation the queen may even reveal shes had the vaccine to be confidence it is extremely important these people get the vaccine so we need to find a way how to communicate it to them and how to in a way isolate them from these damaging examples of misinformation that they sing on social media and i think it is the role they help provide its role for the Community Leaders to actually go out and try to explain to them what they seeing as social media is actually not always the truth. The eyes of the world are of the u. K. This week with governments keen to see not just how it tackles the logistical challenges but how it sells this vaccine to a public being asked to keep pace with science are listing a look now at some of the other stories that are making headlines around the world the german chancellor Angela Merkel says that the current restrictions will not get the country through the winter shes pushing for a decision on tougher restrictions before the Christmas Holidays the state of bavaria is already talking measures asking people to stay at home with only if you except. For maybe in a Prime Minister a little age or bond has resigned from office after his center right party came in 2nd in parliamentary elections the opposition social democrats won the most votes but have no clear majority and no obvious Coalition Partner the postelection wrangling to form a new Coalition Government is now expected. Polls have closed and gone as president ial and parliamentary elections is expected to be a tight race between the come but not a coup otto and his longtime rival John Muhammad gone is considered one of the most politically stable countries in africa but the coronavirus has plunged the country into economic crisis. The European Union and the United States say they will not recognize the results of venezuelas parliamentary elections it handed president Nicolas Maduro control of the National Assembly and cemented his position in power the socialist won almost 70 percent of the vote but turnout was just 31 percent after all physician parties called for a boycott International Observers condemned the vote and more than a dozen latin american countries have rejected the results venezuelas selfproclaimed acting president won why go as called the vote a fraud. So little us influence who are scared of the people are the ones who commit fraud madieu rule and his regime have lost the popular will the majority of us want change in venezuela dont be surprised if they try to advance their assault in the coming days of december because this election has done them no good deal they know when you. Are w. s oscars linker he is in caracas with the latest tonight good evening to you whats going to happen now one has the backing of the United States and he says hes not going to give up hes not going anywhere. Well this upcoming was expected and you know opposition has launched their own of their own of whether to try or vote in which they are asking those of us to reject yesterdays election this is tricky because many people here dont have access to the net this is a this complex but people will be able to cast their ballots on the 12th of the summer how effective this will be is unpredictable what the opposition is aiming to do is have some kind of tangible evidence that they have the support base for Movement Leaders distro no longer be around and institution such although that really didnt help much either with congress i guess the question of who was banned by the military and this group were. How you know i need is the opposition in the country. Well you know being the opposition has always been a struggle here in 2015 when they won a majority of the seats in congress it was because they really didnt go you know and to those elections as a long but really the only thing and many of the opposition have in common is that they want to go out and each Political Movement has their own idea on how to do it when one of them fails and they disband so its not easy to bring in and keep them together and we know that voter turnout was very low that does not speak well for madeira and his allies doesnt. 100. 00 government is criticizing the media claim that 31 percent of voter turnout where the same and remain as recent prometrium election and nobodys criticizing them but we have to take into account that the credibility behind this election was very low to start with also there was pressure to vote from the government toward citizens who receive food in those aids from the state state mourners were also forced to go and see a lot of this voter turnout seemed to many in the opposition much lower than what was officially announced this pipe to be our count was expected the last month those allies are supporting his claims and he will do whatever necessary to win the forces hardest part is the gentleman who will give us an legitimacy over congress ok. D. W. s oscars like it with the latest on that election have been its way look tonight oscar as always thank you. Youre watching the news ill be back at the top of the hour with more world news followed by the day i hope to see you then. The fight against the corona virus pandemic. Has the rate of infection been developing what does the latest research say. Information and context around a virus update. On t. W. And you you may know heres heres were going to you and how the last years german chancellor will bring you back off as youve never have before surprised yourself with what is possible who is medical really what moves them part of who talks to people who follow along the way admirers and critics alike how is the worlds most powerful woman shaping her legacy joining us from eccles last stop. Using a u. V. Lamp to kill the coronavirus thats just one light bulb moment and a multitude of responses to the 19 fluid was repurposed and Hand Sanitizer at the beginning of the pandemic the speed of innovation amid coronavirus could be a game changer experts say it could revolutionize Global Health care. Allowing us to come up with solutions that could change Health Care Delivery. They say necessity is the mother of invention the coronavirus pandemic has thrown that into stark relief from innovations enabling us to live with the realities of the virus to devices that make it stay texan possible heres the story of 2 entrepreneurs who say a diagnosis is just a breath away. Rather than christoph and thomas wolfe have a vision they want to return some normality to this called in 1000 times for months the been working on a breath test that can identify the Novel Coronavirus theyre now confident it works to human organs from a technical point of view this device can get to areas where normally only a dog can sniff things out. A device thats almost as sensitive as a dogs noles the technique is similar to a breathalyzer. This is a stimulus when what we have here is a star and mouthpiece. And you take off the packaging and then what happens you blow into the mouthpiece and you just breathe. In there start out the brothers develop highly Sensitive Sensor Technology from aspect troll meters for industry and labs for a new type of diagnosis in real time. And we can see all sorts of things using breath analysis like whether a patient had coffee yesterday afternoon or not we can identify his Nutritional Status and we can see different amino acids different fatty acids all of this from the breath breath as a direct window into the human body. The brothers believe it could recognize carbon 19 other researchers also say breath analysis could work in principle to test for the corona virus. The challenge is to is to get the. Methods that you run on the equipment the way the equipment is used to chew on and the analytical technique of mice with verified biomarkers are reliable. Once weve proven that then you have a curve igniting breath test ready to go conventional swab tests are reliable but often only carried out when the infection has been there for a while and a result usually takes 2 days the breath test detects metabolic changes in breathing caused by the virus while it is not yet 100 percent reliable it does give an immediate result. The researchers believe that they will be able to deploy the tests as early as next summer in places like football stadiums. Passengers could also be tested at airports before check in the accuracy of the test is currently around 80 percent however the researchers are expecting efficiency to increase significantly in the meantime a lot of detailed work remains to be done. People are complicated and youre looking for a small signal in a snowstorm a blizzard of information. But. Weve found weve found the signals we think are helpful Young Christophe and thomas both originally developed their test for very different types of diagnosis one problem with a covered 1000 tests is that they have not yet been able to carry out studies on patients with the virus they are hoping for to go into the next sisters of processors access to resources to allow us to carry out a validation study on the site in a hospital or an Airport Test Center and with that it becomes very easy to determine whether this would be a way to bring back some normality to peoples. Analyzes could be a way to detect carbon 1000 infections much faster than before. Matthew harris joins us now hes a clinical senior lecturer and Public Health at the Imperial College london matthew so glad you can join us now youve written and the scientific journal nature about how the response occulted 19 has been distinguished by socalled frugal innovations what exactly does that mean well thank you through litigation really is the term that we give to the kind of innovation we see in the resource constraints or situations of extraordinary time pressure or situations where we dont have the kind of resources that we normally like to have when we where we develop Health Care Innovations the work froogle oftentimes is referred to as sort of cheap or good enough innovation that actually frugal innovation is health care to patients thats actually as effective as the kind of innovation you would normally see but just in a way that is far more affordable far more sustainable maybe if you are sort of complexity or functionality but that gets the job and undercoat it of course weve seen around the world some extraordinary difficult situations at National Level in terms of exposing the fragilities a lot of systems but also the real increase in healthcare demands and it really has necessitated a new type of innovating in innovating that pace rapidly using resources that we just find around us so kind of improvising if you are. This is the kind of innovation that we call through innovation so its about reacting quickly using what you have but they havent examples of what a frugal innovation could be. Well absolutely in the early days of the covert response we saw in this in several developing countries and really interesting examples of frugal innovations so for example where there was a lack of personal protective equipment we saw a clinicians improvised the use of simple acetate sheets the kind of such as a shes used to overhead projectors in the old days and by simply putting some holes in either side of the s. K. Sheeting threading some ribbon on either side those became very effective face vices to protect not only the clinician but also the patients in front of them when they were interfacing and this was of course extremely cheap and actually very very effective since then baseball is a vote and become more sophisticated but it was a very good example of a frugal innovation at a time another good example of innovating at a pace was the construction of hospitals in under 10 days in china d actually eventually also in the u. K. Where im from we saw the construction or repurchasing at least of Conference Center has ensued into intensive care units and hospitals also in very very short amounts of time as a sort of idea of repurchasing the resources you have but also very very quickly the characteristic of really innovation now that the crisis has focused minds and mobilize so much in terms of responses as youve told us there is also kind of dialed down side to this kind of concentration of response to the crisis. Well i think the pope it obviously has recorded a deviation of resources from other health care to focus our attention on covert response and as a result some other areas have if you like suffered in terms of Research Going into them and also the Health Care Delivery the different clinical conditions i dont think theres a downside to frugal innovation and i think its been a really revealing how weve been able to develop such Effective Health care responses in a short period of time. Without spending on safety checks or effectiveness or clinical effectiveness or for the patients that we serve so i dont see a downside to through innovation which tends to be foer fordable the Healthcare Systems as long as the necessary checks and balances are in place to ensure the safety of those devices or technologies youve written that this kind of innovation could lead to a leveling in Global Health care equality what does that look like. What is the level in the sense that it has made us really reflect on the fragilities in the Health Systems even in the high Income Countries settings and its made us pay much more attention to the kind of innovations that arise from the low Income Countries its something weve been up to pacing for for many years and what code is doing is making us pay more attention to settings that traditionally we havent really noticed in terms of Healthcare Innovation thank you Matthew Harris there talking about putting Human Resource lowness at the center of our cove in 1000 response is a clinical senior lecturer and Public Health at Imperial College london thank you for your insights. And now its time for one of your son and questions about the coronavirus our science correspondent Derrick Williams is ready with announcer. Taking into account to patients sex and age what do the statistics say about complications. One of the clearest pieces of information thats come out of the statistics is that from the age of about 40 on women in general are a lot less likely than men to have severe Outcomes Data from both the c. D. C. And the European Center for disease prevention and control a reveal how stark the difference is this graphic for example emphasizes how much more likely men of a certain age are to end up in the hospital or the i. C. U. Numbers of men are represented by the blue bar and a numbers of women by the red one in europe men between 40 and 80 make up around 3 quarters of all intensive care cases and recorded deaths after 80 the split is more even but thats almost certainly due to the simple fact that a lot fewer men live to that age so statistically the chances are a lot higher that in the over eightys a woman is going to get coke at 19 ben a man is going to get it theres a lot of speculation about why and there and there doesnt seem to be a single reason that accounts for all of the discrepancy im several factors are likely playing roles we know though that people who have diabetes or high Blood Pressure or Heart Disease are at greater risk of severe outcomes if they contract had 19 and aging men are more likely to have those comorbidities than aging women are but another possible contributing factor involves immune response the male and female immune systems. Different experts say because on their 2nd x. Chromosome women have another copy of many of the genes that are involved in fighting off disease its been theorized thats also why women are more likely to develop certain auto immune diseases than men but in this case it could be helping them keep covert 19 or its medical ramifications more effectively a bad thats hard to prove though. And thats all from us thank you very much for watching and stay safe. In australian on the brink of extinction. Thousands of young lives were killed by devastating bushfires. And the surviving can are staring into the eyes of yet another catastrophe. After the inferno the battle to save australias cause is. Close up. On t. W. Imagine how many push old loves us right now from the war right now Climate Change to bring off the store. Faces much less the way for just one week. How much work can really get it. We still have time to an ongoing. Success. To subscribe and more of the news like this. Whats the secret behind this classic. Visit to south. As soon as youre beethoven to lose your mind. Or the story behind the music. Was a hit for the ages pretty soon. Oh. Ah. Tobins 9th symphony for the world starts to simmer going on w

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