Dual Therapy Stent Market Forecast, Trend Analysis & Competition Tracking - Global Review 2017 to 2027
factmrMay 7, 2021
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Dual therapy stent is a coronary artery stent that is based on the combined engineering of biotechnology, and drug-eluting stents to perform functions such as accelerated vessel healing and inhibits cell proliferation. Dual therapy stent is considered as next-generation stents. Drug-eluting stent is constructed through the addition of bone marrow-derived CD34þ endothelial progenitor cell capture system on the luminal stent surface. This technology of dual therapy stent enables them to elute either cytostatic drugs such as everolimus, sirolimus, and zotarolimus or cytotoxic drugs such as paclitaxel which aids in inhibiting of migration and proliferation of vascular smooth muscle cells and restenosis. Dual therapy stent is advantageous as compared to drug-eluting stents and bare metal stents as they offer lower rates of in-stent restenosis, and requires subsequent medical interventions. Dual therapy stent is a combination of an abluminal biodegradable drug-eluting coating and a luminal layer. This advancement modification results in attraction of circulating endothelial progenitor cells which can self-differentiate into endothelium cells. The first dual therapy stent is generated by an additional coating of anti-CD34 antibodies restricted on stent platform to improve deprived endothelialization coupled with drug-eluting stents. This results in binding of antibodies to the CD34 membrane and expressed on cell surface of endothelial progenitor cells to endorse coronary vascular repair process and lowers neointimal hyperplasia.