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DGAP-News: AFFiRiS AG
/ Key word(s): Conference/Study
AFFiRiS AG: Positive preclinical in vivo results with AFFiRiS' antibody mAB C6-17 to treat Huntington's disease to be presented at the 16th Annual Huntington's Disease Therapeutics Conference
27.04.2021 / 09:00
Positive preclinical
in vivo results with AFFiRiS' antibody mAB C6-17 to treat Huntington's disease to be presented at the 16
th Annual Huntington's Disease Therapeutics Conference
- Monoclonal antibody C6-17 designed to target mutant huntingtin protein (mtHTT) and to reduce spread of Huntington's disease pathology
- Human mtHTT transgenic mice treated with mAB C6-17 showed significantly reduced mtHTT levels in peripheral organs and central nervous system and displayed improved motor performance